What is the most common genetic mutation found in esophageal cancer biopsies?
Understand the Problem
The question is asking for information regarding the most frequent genetic mutation identified in biopsies of esophageal cancer, providing multiple choice options for selecting the correct answer.
Answer
TP53 point mutations
The most common genetic mutation found in esophageal cancer biopsies is TP53 point mutations.
Answer for screen readers
The most common genetic mutation found in esophageal cancer biopsies is TP53 point mutations.
More Information
TP53 mutations are commonly associated with various types of cancer, including esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC). They can be found in precancerous lesions as well, indicating their role in cancer progression.
Tips
A common mistake is to confuse TP53 mutations with other gene mutations that may occur less frequently.
Sources
- Ordering of mutations in preinvasive disease stages of esophageal - pmc.ncbi.nlm.nih.gov
- Somatic mutations of esophageal adenocarcinoma: a comparison - nature.com
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