What is the function of the Cleavage and Polyadenylation Specificity Factor (CPSF) during transcription termination?
Understand the Problem
The question is asking about the specific function of the Cleavage and Polyadenylation Specificity Factor (CPSF) in the process of transcription termination. It provides multiple-choice answers related to CPSF's role, particularly focusing on how it interacts with RNA during the transcription process.
Answer
CPSF cleaves the 3' region of pre-mRNA for transcription termination and 3'-end processing.
The final answer is CPSF is involved in the cleavage of the 3' signaling region from a newly synthesized pre-mRNA molecule and is key to transcription termination and mRNA 3'-end processing.
Answer for screen readers
The final answer is CPSF is involved in the cleavage of the 3' signaling region from a newly synthesized pre-mRNA molecule and is key to transcription termination and mRNA 3'-end processing.
More Information
CPSF is crucial for adding the poly(A) tail during mRNA maturation, thus encouraging the stability and translation efficiency of the mRNA.
Tips
Failing to distinguish between the cleavage function and polyadenylation. Remember that cleavage occurs first, followed by the addition of the poly(A) tail.
Sources
- Cleavage and Polyadenylation Specificity Factor - Wikipedia - en.wikipedia.org
- Cleavage and polyadenylation: Ending the message expands gene ... - pmc.ncbi.nlm.nih.gov
- Cleavage and Polyadenylation Specificity Factor - ScienceDirect.com - sciencedirect.com
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