What is the fate of glycine in heme synthesis?
Understand the Problem
The question is asking about the role of glycine in the process of heme synthesis and what specific reaction or outcome occurs involving glycine in that context.
Answer
Glycine condenses with succinyl-CoA to form δ-aminolevulinic acid (ALA) in heme synthesis.
Glycine condenses with succinyl-CoA to form δ-aminolevulinic acid (ALA) in the mitochondrial matrix, marking the first step in heme synthesis.
Answer for screen readers
Glycine condenses with succinyl-CoA to form δ-aminolevulinic acid (ALA) in the mitochondrial matrix, marking the first step in heme synthesis.
More Information
Glycine plays a crucial role in the early stages of heme synthesis. Its interaction with succinyl-CoA is critical for forming δ-aminolevulinic acid, which is the first precursor in the biosynthesis of heme. This process occurs in the mitochondria and is essential for the production of heme, a vital component of hemoglobin.
Tips
A common mistake is confusing the production of δ-aminolevulinic acid with later stages of heme synthesis. Ensure to understand the initial step involving glycine and succinyl-CoA.
Sources
- Heme Synthesis - an overview | ScienceDirect Topics - sciencedirect.com
- Heme, whence come thy carbon building blocks? - ASH Publications - ashpublications.org
AI-generated content may contain errors. Please verify critical information
