What is the diagnostic approach for unexplained hypoglycemia?

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Understand the Problem

The question is asking about the diagnostic approach to unexplained hypoglycemia, specifically whether it is related to meals and the subsequent testing based on various insulin and C-peptide levels.

Answer

Evaluate meal relation, then measure plasma insulin and C-peptide levels.

The flowchart provides a detailed diagnostic approach, first considering meal-related causes, then evaluating insulin and C-peptide levels to determine endogenous or exogenous causes.

Answer for screen readers

The flowchart provides a detailed diagnostic approach, first considering meal-related causes, then evaluating insulin and C-peptide levels to determine endogenous or exogenous causes.

More Information

Understanding whether hypoglycemia is related to meals helps determine if the cause is reactive hypoglycemia or related to insulin production or action.

Tips

A common mistake is not confirming the relationship to meals, which can lead to missing a diagnosis of reactive hypoglycemia.

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