What is mainly responsible for the orientation of membrane proteins?
Understand the Problem
The question is asking about the factors that determine how membrane proteins are oriented within a cell membrane. It presents multiple-choice options regarding the potential influences on this orientation.
Answer
Topogenic sequences determine membrane protein orientation.
The orientation of membrane proteins is mainly determined by their topogenic sequences, which guide how proteins are inserted into a membrane during synthesis.
Answer for screen readers
The orientation of membrane proteins is mainly determined by their topogenic sequences, which guide how proteins are inserted into a membrane during synthesis.
More Information
Topogenic sequences in the amino acids of the protein specify their orientation by indicating the way the protein should insert itself into the membrane. This is crucial for the function of transmembrane proteins.
Sources
- what determines the orientation of proteins in the membrane - sciencedirect.com
- Membrane Proteins - Molecular Biology of the Cell - ncbi.nlm.nih.gov
