What characterizes the initial phase of drug administration via IV when absorption is not a factor?
Understand the Problem
The question is asking about the characteristics of the initial phase of drug administration through intravenous (IV) methods, specifically when absorption is not relevant. We need to identify the correct phase that corresponds to the given options in relation to IV drug administration.
Answer
Immediate direct entry into the bloodstream with consistent time to peak effect.
The initial phase of drug administration via IV is characterized by the immediate and direct entry of the drug into the bloodstream without absorption being a factor, resulting in consistent time to peak drug effect.
Answer for screen readers
The initial phase of drug administration via IV is characterized by the immediate and direct entry of the drug into the bloodstream without absorption being a factor, resulting in consistent time to peak drug effect.
More Information
IV drug administration leads to immediate therapeutic effect because the drug bypasses the digestive tract and first-pass metabolism in the liver, which can alter the concentration of a drug that is administered orally.
Tips
A common mistake is confusing the concept with intramuscular or oral administration where absorption is a critical factor.
Sources
- Intravenous Route - an overview | ScienceDirect Topics - sciencedirect.com
- Intravenous Drug Administration - an overview | ScienceDirect Topics - sciencedirect.com
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