What causes excessive outward flow of fluid into the interstitial compartment during inflammation?
Understand the Problem
The question is asking about the physiological mechanisms that lead to the excessive outward flow of fluid into the interstitial space during inflammation. It is likely seeking an explanation of factors that alter pressure or permeability influences.
Answer
Increased capillary hydrostatic pressure from inflammation causes excessive fluid outflow.
The excessive outward flow of fluid into the interstitial compartment during inflammation is primarily caused by an increase in capillary hydrostatic pressure. This can occur as a result of venous obstruction or arteriolar dilation associated with inflammation.
Answer for screen readers
The excessive outward flow of fluid into the interstitial compartment during inflammation is primarily caused by an increase in capillary hydrostatic pressure. This can occur as a result of venous obstruction or arteriolar dilation associated with inflammation.
More Information
During inflammation, certain responses such as arteriolar dilation lead to increased capillary hydrostatic pressure, which pushes more fluid into the interstitial space, contributing to edema.
Tips
A common mistake is not accounting for the role of capillary permeability and lymphatic drainage in edema. While hydrostatic pressure is a key factor, changes in these can also influence fluid balance.
Sources
- What causes excessive outward flow of fluid - sciencedirect.com
- Pathophysiology of Edema Formation - Capillary Fluid Exchange - ncbi.nlm.nih.gov
- Pathophysiology of tissue fluid accumulation in inflammation - Wiig - physoc.onlinelibrary.wiley.com
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