The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalyzed by 4 enzymes. These act in the following order: Acetyl CoA de... The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalyzed by 4 enzymes. These act in the following order: Acetyl CoA dehydrogenase, enoyl hydratase, D-OH acyl CoA dehydrogenase, thiolase. Substrate level phosphorylation in TCA cycle is in step: Isocitrate dehydrogenase, Malate dehydrogenase, Aconitase, Succinate thiokinase. One molecule of glucose gives how many molecules of CO2 in TCA cycle? In TCA cycle, succinate is converted to ketoglutarate by the enzyme: Fumarase, Isocitrate dehydrogenase, Aconitase, Succinate. The initial step of the citric acid cycle is: Conversion of pyruvate to acetyl-CoA, Condensation of acetyl-CoA with oxaloacetate, Conversion of citrate to isocitrate, Formation of α-ketoglutarate catalyzed by isocitrate dehydrogenase. Read more

Understand the Problem

The question is asking about metabolic processes related to fatty acids and the TCA cycle, highlighting the enzymes involved and the number of CO2 molecules produced from glucose. It is focused on biochemical pathways and enzyme functions.

More Information

The TCA cycle yields 6 CO2 per glucose because each pyruvate yields 3 CO2, and glucose splits into 2 pyruvate. The conversion error in question 69 stems from incorrect enzyme pairing—succinate dehydrogenase converts succinate to fumarate, not α-ketoglutarate. The initial TCA cycling begins with the condensation of acetyl-CoA with oxaloacetate, crucial for citrate formation.

Tips

Check the specific enzyme roles in metabolic pathways to avoid pairing errors. Misidentifying catalytic processes leads to logical errors, especially in enzyme functions.

Sources

• Oxidation of Fatty Acids - Chemistry LibreTexts - chem.libretexts.org
• Biochemistry, Fatty Acid Oxidation - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov