Mr. Manu, a 54 year old diagnosed with a bowel tumour, was told by his physician that the cells in his bowel tumour are poorly differentiated. He asked you as a Nurse on duty what... Mr. Manu, a 54 year old diagnosed with a bowel tumour, was told by his physician that the cells in his bowel tumour are poorly differentiated. He asked you as a Nurse on duty what is meant by 'poorly differentiated'. A. The tumour cells look more immature than normal bowel cells. B. The cells in the tumour are mutated.
Understand the Problem
The question is asking for an explanation regarding the term 'poorly differentiated' in the context of tumor biology, specifically how it relates to the appearance and characteristics of tumor cells compared to normal cells. It implies a need for understanding the implications of tumor cell differentiation.
Answer
The tumour cells look more immature than normal bowel cells.
The tumour cells look more immature than normal bowel cells.
Answer for screen readers
The tumour cells look more immature than normal bowel cells.
More Information
In the context of cancer, 'poorly differentiated' means that the cancer cells do not resemble the normal cells from which they originated. They appear more immature and have lost the differentiations typical of normal cells, which often makes them more aggressive.
Tips
A common mistake is thinking 'poorly differentiated' simply means the cells are mutated. While mutation can occur, it specifically indicates the cells look less mature and unlike the original tissue.
Sources
- Grades and types of bowel cancer - cancerresearchuk.org
- Understanding Your Pathology Report: Colon Cancer | OncoLink - oncolink.org
- Staging and grading of bowel cancer - Macmillan Cancer Support - macmillan.org.uk
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