Look at images A and B, in which the fluorescence reveals the cellular location of the T antigen labeled by this means. Which of the following events may have occurred to the prote... Look at images A and B, in which the fluorescence reveals the cellular location of the T antigen labeled by this means. Which of the following events may have occurred to the protein in image B?
Understand the Problem
The question involves analyzing two images that show the cellular location of a T antigen, and it asks which events may have occurred to the protein in image B. This requires understanding of fluorescence microscopy and protein localization.
Answer
The NLS has some mutation.
The NLS has some mutation.
Answer for screen readers
The NLS has some mutation.
More Information
The nuclear localization signal (NLS) is crucial for transporting proteins into the nucleus. Mutations in the NLS can prevent proteins from correctly localizing to the nucleus, resulting in their presence in the cytoplasm instead.
Tips
A common mistake is assuming an amino acid deletion would not affect localization. However, even small changes in key sequences like the NLS can have significant impacts.
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