Lewis Family Study: Answer the following questions using the pedigree. Show all your work (i.e., Punnett squares). 1. ABO phenotype of #1 2. Secretor genotype of #3 3. Lewis phenot... Lewis Family Study: Answer the following questions using the pedigree. Show all your work (i.e., Punnett squares). 1. ABO phenotype of #1 2. Secretor genotype of #3 3. Lewis phenotype of #3 4. Most probable ABO genotype of #4 5. Substances in saliva of #5 6. Lewis phenotype of #4.
Understand the Problem
The question is asking to analyze a pedigree chart to answer several genetics-related questions about ABO and Lewis phenotypes and genotypes based on the given family study. This will involve using Punnett squares and understanding inheritance patterns.
Answer
1: A, 2: SeSe, 3: Le(a-b+), 4: AO, 5: A and B antigens, 6: Le(a-b+)
- ABO phenotype of #1 is A. 2. Secretor genotype of #3 is SeSe. 3. Lewis phenotype of #3 is Le(a-b+). 4. Most probable ABO genotype of #4 is AO. 5. Substances in saliva of #5 are A and B antigens. 6. Lewis phenotype of #4 is Le(a-b+).
Answer for screen readers
- ABO phenotype of #1 is A. 2. Secretor genotype of #3 is SeSe. 3. Lewis phenotype of #3 is Le(a-b+). 4. Most probable ABO genotype of #4 is AO. 5. Substances in saliva of #5 are A and B antigens. 6. Lewis phenotype of #4 is Le(a-b+).
More Information
The pedigree chart helps trace inheritance of specific traits, like ABO and Lewis types. The presence of the Se gene determines if ABH antigens are secreted in bodily fluids. The Lewis phenotype is based on the presence/absence of Lea and Leb antigens.
Tips
Make sure to observe inheritance patterns carefully, especially regarding dominant and recessive traits.
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