In parkinsonism, what receptors does dopamine act on to exhibit beneficial effects?
Understand the Problem
The question is asking about the specific receptors that dopamine interacts with in the context of Parkinsonism, and how these interactions lead to beneficial effects. This indicates a focus on neuropharmacology and the mechanisms of dopamine in treating Parkinson's disease.
Answer
D2 receptors
Dopamine acts on D2 receptors (which includes D2 and D3 receptors) to exhibit beneficial effects in Parkinson's disease.
Answer for screen readers
Dopamine acts on D2 receptors (which includes D2 and D3 receptors) to exhibit beneficial effects in Parkinson's disease.
More Information
Dopamine's beneficial effects in Parkinson's disease primarily involve activation of D2 receptors, which includes both D2 and D3 subtypes. Pharmaceutical agents may also stimulate D1 receptors to some extent.
Tips
A common misconception is that all dopamine receptors equally contribute to Parkinson's disease treatments. While several types are involved, D2 receptors play the most crucial role.
Sources
- Dopamine and Parkinson's Disease - NCBI - ncbi.nlm.nih.gov
- Implication of dopamine D3 receptor activation in the reversion of... - nature.com
