How may chronic hypoxia contribute to cell injury?
Understand the Problem
The question is asking how chronic hypoxia can lead to cellular injury, offering multiple-choice options that suggest different mechanisms such as free radical formation, protein denaturation, or calcification.
Answer
Chronic hypoxia drops ATP levels, disrupts cellular functions, and may cause cell death. It causes oxidative stress and inflammation.
Chronic hypoxia can contribute to cell injury by causing a drop in ATP levels, leading to an inability to maintain cellular functions. Prolonged hypoxia can result in cell death. It also triggers oxidative stress, inflammation, and can cause damage to proteins, lipids, and DNA.
Answer for screen readers
Chronic hypoxia can contribute to cell injury by causing a drop in ATP levels, leading to an inability to maintain cellular functions. Prolonged hypoxia can result in cell death. It also triggers oxidative stress, inflammation, and can cause damage to proteins, lipids, and DNA.
More Information
Chronic hypoxia affects the body's ability to distribute and use oxygen efficiently, with serious implications for vital organs like the heart and brain.
Tips
Ignoring the difference between acute and chronic hypoxia can lead to misunderstanding its effects. Prolonged oxygen deprivation has more severe consequences.
Sources
- Pathophysiological implications of hypoxia in human diseases - PMC - ncbi.nlm.nih.gov
- Effects of Microvesicles on Cell Apoptosis under Hypoxia - Guo - 2019 - onlinelibrary.wiley.com
- Hypoxia & cellular injury - causes, symptoms, diagnosis ... - YouTube - youtube.com
