How does a cytotoxic T cell induce apoptosis in a target cell?
Understand the Problem
The question is asking about the mechanism by which cytotoxic T cells induce apoptosis in target cells, focusing on the specific actions they take, such as using ligands or releasing proteins.
Answer
Cytotoxic T cells induce apoptosis using perforin to form pores and granzymes to trigger apoptotic pathways.
Cytotoxic T cells induce apoptosis by releasing perforin and granzymes; perforin forms pores in the target cell membrane, allowing granzymes to enter and trigger apoptotic pathways.
Answer for screen readers
Cytotoxic T cells induce apoptosis by releasing perforin and granzymes; perforin forms pores in the target cell membrane, allowing granzymes to enter and trigger apoptotic pathways.
More Information
Perforin forms pores in the target cell membrane to facilitate the entry of granzymes, which then activate cellular enzymes that fragment DNA, ultimately leading to apoptosis.
Sources
- The web page with info on - Example Source - ncbi.nlm.nih.gov
