How do transcription factors facilitate the connection between distal elements and genes?
Understand the Problem
The question is asking about the role of transcription factors in the interaction between distal regulatory elements and genes, specifically which mechanism they utilize to facilitate this connection.
Answer
Transcription factors connect distal elements to genes by binding enhancers and interacting with mediator proteins.
Transcription factors facilitate the connection between distal elements, like enhancers, and target genes by binding to these elements and then interacting with mediator proteins. This interaction helps bridge the enhancer to the promoter region of the gene, affecting its transcription.
Answer for screen readers
Transcription factors facilitate the connection between distal elements, like enhancers, and target genes by binding to these elements and then interacting with mediator proteins. This interaction helps bridge the enhancer to the promoter region of the gene, affecting its transcription.
More Information
Transcription factors are key regulators of gene expression, allowing cells to respond to various developmental and environmental cues by modulating the transcription of target genes.
Tips
A common mistake is thinking that enhancers and transcription factors act directly on the promoter without the need for mediator proteins.
Sources
- Eukaryotic Transcription Gene Regulation | Biology for Majors I - courses.lumenlearning.com
- Eukaryotic Transcription Gene Regulation - Biology LibreTexts - bio.libretexts.org
AI-generated content may contain errors. Please verify critical information
