How do CD4 T helper 1 cells primarily assist macrophages?
Understand the Problem
The question is asking about the primary function of CD4 T helper 1 cells in relation to macrophages, specifically how they assist them. We are looking for the option that best describes this interaction, which typically involves cytokine signaling.
Answer
CD4 T helper 1 cells produce IFN-γ to activate macrophages.
The final answer is CD4 T helper 1 cells assist macrophages primarily by producing IFN-γ cytokine, which activates macrophages to promote intracellular killing of pathogens.
Answer for screen readers
The final answer is CD4 T helper 1 cells assist macrophages primarily by producing IFN-γ cytokine, which activates macrophages to promote intracellular killing of pathogens.
More Information
CD4 T helper 1 cells (Th1) are crucial in the immune response, particularly in combating intracellular pathogens like viruses and certain bacteria by activating macrophages.
Tips
A common mistake is confusing the role of Th1 cells with Th2 cells, which are more involved in humoral immunity and activating B cells.
Sources
- Macrophage activation by armed CD4 TH1 cells - NCBI - ncbi.nlm.nih.gov
- T helper cell - Wikipedia - en.wikipedia.org
- Helper T Cells - Beckman Coulter - beckman.com
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