How do bacterial topoisomerase IV enzymes function during DNA replication?
Understand the Problem
The question is asking about the specific role of bacterial topoisomerase IV enzymes in the process of DNA replication. It requires an understanding of the mechanisms of DNA replication and the actions performed by topoisomerases.
Answer
Topoisomerase IV disentangles newly replicated DNA, aiding in chromosome segregation.
Bacterial topoisomerase IV functions during DNA replication by disentangling newly replicated DNA and enabling the segregation of daughter chromosomes. It is involved in unlinking daughter chromosomes and resolving DNA knots, ensuring DNA segregation and proper cell division.
Answer for screen readers
Bacterial topoisomerase IV functions during DNA replication by disentangling newly replicated DNA and enabling the segregation of daughter chromosomes. It is involved in unlinking daughter chromosomes and resolving DNA knots, ensuring DNA segregation and proper cell division.
More Information
Topoisomerase IV is crucial for resolving topological problems during DNA replication by removing supercoils and disentangling sister chromatids, a vital step for proper chromosome segregation in bacterial cells.
Tips
A common mistake is confusing topoisomerase IV's function with that of gyrase, another type of topoisomerase that is primarily responsible for relieving torsional strain ahead of the replication fork.
Sources
- DNA Topoisomerase IV - an overview | ScienceDirect Topics - sciencedirect.com
- The web page with info on - Nature - nature.com
AI-generated content may contain errors. Please verify critical information
