Delayed absorption usually results in a decreased Cmax and a shorter Tmax. A) True B) False
Understand the Problem
The question is asking whether delayed absorption leads to a decrease in the maximum concentration (Cmax) and a shorter time to reach that concentration (Tmax). We need to analyze the pharmacokinetics principles related to drug absorption to determine the answer.
Answer
False
Delayed absorption usually results in a decreased Cmax and a longer Tmax. Therefore, the statement is False.
Answer for screen readers
Delayed absorption usually results in a decreased Cmax and a longer Tmax. Therefore, the statement is False.
More Information
In pharmacokinetics, delayed drug absorption typically causes the time to reach the maximum concentration (Tmax) to be extended, not shortened, and the maximum concentration (Cmax) to decrease.
Tips
Confusing the relationship between absorption rate and Tmax/Cmax changes is common. Remember that delayed absorption prolongs Tmax and lowers Cmax.
Sources
- Impact of gastrointestinal physiology on drug absorption in special ... - sciencedirect.com
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