Classification of Anesthetics: Esters and Amides.
Understand the Problem
The content in the image provides a classification of anesthetics into two categories: Esters and Amides, including their characteristics and examples. It highlights differences in their metabolism, duration of action, and generic names.
Answer
Esters vs Amides anesthetics: metabolism, duration, stability differences.
The image provides a classification of local anesthetics into esters and amides based on their duration of action, metabolism, stability, and common examples. Esters are metabolized in plasma and have a shorter duration, while amides are metabolized in the liver and are more stable.
Answer for screen readers
The image provides a classification of local anesthetics into esters and amides based on their duration of action, metabolism, stability, and common examples. Esters are metabolized in plasma and have a shorter duration, while amides are metabolized in the liver and are more stable.
More Information
Esters like cocaine, procaine, and tetracaine are metabolized quickly in plasma, resulting in shorter durations and potential allergies. Amides like lidocaine are processed in the liver, offering prolonged action and greater stability.
Tips
Confusing esters and amides regarding metabolism and action duration is common; remember that esters are plasma-metabolized with shorter effects.
Sources
- Local Anesthetic Pharmacology - SpringerLink - link.springer.com
- Local Anesthetics: Review of Pharmacological Considerations - PMC - pmc.ncbi.nlm.nih.gov
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