Application of allosteric modulators
Understand the Problem
The question is asking about the various uses and implications of allosteric modulators in biological systems, particularly in pharmacology and biochemistry. Allosteric modulators are compounds that bind to a site other than the active site on a protein, influencing its activity, which can have significant therapeutic applications.
Answer
Used for conditions like Parkinson's, Alzheimer's, offering alternative treatments and enhanced selectivity.
Allosteric modulators are used in drug discovery to provide alternative treatments for diseases like Parkinson's disease, schizophrenia, Alzheimer's, and to improve motor functions. They offer greater selectivity and can modify receptor responses, enhancing or inhibiting effects.
Answer for screen readers
Allosteric modulators are used in drug discovery to provide alternative treatments for diseases like Parkinson's disease, schizophrenia, Alzheimer's, and to improve motor functions. They offer greater selectivity and can modify receptor responses, enhancing or inhibiting effects.
More Information
Allosteric modulators, by binding to non-competitive sites, can provide high selectivity and cause fewer side effects, making them promising agents in drug discovery.
Sources
- Impact of Allosteric Modulation in Drug Discovery - NCBI - ncbi.nlm.nih.gov
- Allosteric Modulator - an overview | ScienceDirect Topics - sciencedirect.com
- Allosteric Modulators: An Emerging Concept in Drug Discovery - pubs.acs.org
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