A 27-year-old woman presented at 32 weeks of gestation with preterm labor. Her membrane was ruptured 12 hours ago, and she has been on antibiotics. She received the first dose of s... A 27-year-old woman presented at 32 weeks of gestation with preterm labor. Her membrane was ruptured 12 hours ago, and she has been on antibiotics. She received the first dose of steroids. Which of the following is the most appropriate drug to be given? A. Atosiban B. Ritodrine C. Nifedipine D. Magnesium sulfate
Understand the Problem
The question is asking which medication is most appropriate to administer to a 27-year-old woman in preterm labor at 32 weeks of gestation after her membranes have ruptured. This involves understanding the management of preterm labor and the effects of different medications.
Answer
Magnesium sulfate
The most appropriate drug to be given is magnesium sulfate.
Answer for screen readers
The most appropriate drug to be given is magnesium sulfate.
More Information
Magnesium sulfate is recommended for women at risk of imminent preterm birth before 32 weeks of gestation to prevent neurological complications such as cerebral palsy in the infant. It is not used specifically as a tocolytic to stop contractions, but for fetal neuroprotection.
Tips
A common mistake is to assume magnesium sulfate is used primarily to stop contractions. It's actually used for fetal neuroprotection.
Sources
- WHO recommendations on interventions to improve preterm birth - apps.who.int
- P-PROM, Tocolysis and Delayed Cord Clamping - formularywkccgmtw.co.uk
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