Vitamins D and E Overview
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Questions and Answers

What is the primary pro vitamin D source in human and animal tissues?

  • Cholecalciferol
  • 7-dehydrocholesterol (correct)
  • Ergosterol
  • Calcidiol

Which form of vitamin D is considered the active form?

  • Calcidiol
  • Calcitriol (correct)
  • Ergocalciferol
  • 25-OH-D

Which of the following is a consequence of vitamin D deficiency in children?

  • Bone deformities (Rickets) (correct)
  • Hemolysis of red blood cells
  • Renal stones
  • Infertility

What is a symptom of vitamin E deficiency?

<p>RBC hemolysis (C)</p> Signup and view all the answers

Excessive intake of vitamin D can lead to which of the following conditions?

<p>Calcification of tissues (A)</p> Signup and view all the answers

Flashcards

Vitamin D activation process

Ergosterol (plant) or 7-dehydrocholesterol (human/animal) is converted to vitamin D2(calciferol) by UV light. The liver converts calciferol to 25-hydroxyvitamin D, then the kidneys convert this to the active form, calcitriol.

Vitamin D function

Vitamin D regulates calcium and phosphate levels in the blood and promotes bone health by assisting in calcium and phosphate absorption.

Vitamin D deficiency symptoms

Deficiency in children causes rickets (bone deformities), and in adults, osteomalacia (softened bones).

Vitamin E types

Vitamin E has four forms (tocopherols), but alpha-tocopherol is the most active.

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Vitamin E function

Vitamin E acts as an antioxidant and protects against cell damage and certain diseases, like heart disease, as well as preventing sterility.

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Study Notes

Vitamin D (Calciferol)

  • Vitamin D is a steroid ring
  • Ergosterol is the provitamin D in plants
  • 7-dehydrocholesterol is the provitamin D in humans and animals
  • Vitamin D has 2 forms: D2 and D3
  • Vitamin D activation involves UV light, liver, and kidney
  • Activated forms include calcifediol (25-OH-D) and calcitriol (1,25(OH)2D)

Vitamin D Function

  • Normalizes serum calcium and phosphate levels
  • Normalizes bone by providing calcium and phosphate

Vitamin D Deficiency

  • Rickets in children (bone deformities)
  • Osteomalacia in adults (softening of bones)

Vitamin D Excess (Hypervitaminosis)

  • Abnormal calcification of tissue and deposition of calcium and phosphate in the kidney (renal stones)

Vitamin E (Tocopherols)

  • Four types: α, β, γ, and δ
  • α-tocopherol is the most active form
  • Function:
    • Anti-sterility
    • Antioxidant
    • Protects from atherosclerosis and heart disease (prevents LDL oxidation)

Vitamin E Deficiency

  • RBC hemolysis (due to oxidation) in premature infants
  • Infertility

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Description

This quiz covers essential information about Vitamins D and E, including their structures, functions, and deficiency effects. Participants will explore the roles of these vitamins in human health, such as the impacts of their insufficiency and excess. Test your knowledge on these vital nutrients and their biological significance.

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