5 Questions
Which two forms of Riboflavin are biologically active?
Flavin mononucleotide and flavin adenine dinucleotide
Riboflavin deficiency is characterized by which of the following symptoms?
Dermatitis, cheilosis, and glossitis
What is the primary role of FMN and FAD in flavoenzymes?
Catalyzing the oxidation or reduction of a substrate
Which process involves the transfer of an adenosine monophosphate moiety from ATP to FMN?
Formation of FAD
Which molecules are formed when FMN and FAD accept two hydrogen atoms?
FMNH2 and FADH2
Study Notes
Riboflavin (Vitamin B2)
- The two biologically active forms of riboflavin are flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
- FMN and FAD are formed by the transfer of an adenosine monophosphate moiety from ATP to FMN.
- Both FMN and FAD can reversibly accept two hydrogen atoms, forming FMNH2 or FADH2.
- FMN and FAD are bound tightly, sometimes covalently, to flavoenzymes.
- Flavoenzymes catalyze the oxidation or reduction of a substrate.
Deficiency Symptoms
- Riboflavin deficiency is not associated with a major human disease.
- Deficiency symptoms include dermatitis, a skin condition characterized by inflammation.
- Cheilosis, a symptom of riboflavin deficiency, is characterized by fissuring at the corners of the mouth.
- Glossitis, another symptom, is characterized by the tongue appearing smooth and purplish.
Learn about the biologically active forms of Riboflavin, its role in oxidation and reduction reactions, and the effects of deficiency.
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