Vitamin B2: Riboflavin Structure and Function
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Questions and Answers

Which two forms of Riboflavin are biologically active?

  • Flavin adenine monophosphate and flavin di-nucleotide
  • Flavin mononucleotide and flavin adenine dinucleotide (correct)
  • Riboflavin monophosphate and Riboflavin triphosphate
  • Riboflavin diphosphate and Riboflavin hexaphosphate
  • Riboflavin deficiency is characterized by which of the following symptoms?

  • Hypercalcemia, anemia, and hypotension
  • Osteoporosis, night blindness, and hyperglycemia
  • Dermatitis, cheilosis, and glossitis (correct)
  • Hypertension, hypothyroidism, and tachycardia
  • What is the primary role of FMN and FAD in flavoenzymes?

  • Functioning as neurotransmitters in the nervous system
  • Storing genetic information in cells
  • Catalyzing the oxidation or reduction of a substrate (correct)
  • Acting as electron donors in glucose metabolism
  • Which process involves the transfer of an adenosine monophosphate moiety from ATP to FMN?

    <p>Formation of FAD</p> Signup and view all the answers

    Which molecules are formed when FMN and FAD accept two hydrogen atoms?

    <p>FMNH2 and FADH2</p> Signup and view all the answers

    Study Notes

    Riboflavin (Vitamin B2)

    • The two biologically active forms of riboflavin are flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
    • FMN and FAD are formed by the transfer of an adenosine monophosphate moiety from ATP to FMN.
    • Both FMN and FAD can reversibly accept two hydrogen atoms, forming FMNH2 or FADH2.
    • FMN and FAD are bound tightly, sometimes covalently, to flavoenzymes.
    • Flavoenzymes catalyze the oxidation or reduction of a substrate.

    Deficiency Symptoms

    • Riboflavin deficiency is not associated with a major human disease.
    • Deficiency symptoms include dermatitis, a skin condition characterized by inflammation.
    • Cheilosis, a symptom of riboflavin deficiency, is characterized by fissuring at the corners of the mouth.
    • Glossitis, another symptom, is characterized by the tongue appearing smooth and purplish.

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    Description

    Learn about the biologically active forms of Riboflavin, its role in oxidation and reduction reactions, and the effects of deficiency.

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