Podcast
Questions and Answers
Who is Charles Monet?
Who is Charles Monet?
Frenchman living in Africa who became exposed to a level four virus in Kitum Cave.
What is Mount Elgon?
What is Mount Elgon?
Isolated mountain on the border between Uganda and Kenya that holds Kitum Cave.
What is Kitum Cave?
What is Kitum Cave?
Located on Mount Elgon and holds level 4 viruses.
Who is Dr. Shem Musoke?
Who is Dr. Shem Musoke?
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How did Dr. Musoke continue to spread the virus?
How did Dr. Musoke continue to spread the virus?
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Who is David Silverstein?
Who is David Silverstein?
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What was Dr. Musoke infected with?
What was Dr. Musoke infected with?
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What is a filovirus?
What is a filovirus?
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Which is worse, Ebola Zaire or Ebola Sudan?
Which is worse, Ebola Zaire or Ebola Sudan?
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Why can't a monkey or human be the primary host for the virus?
Why can't a monkey or human be the primary host for the virus?
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Who is Nancy Jaax?
Who is Nancy Jaax?
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What does USAMRIID stand for?
What does USAMRIID stand for?
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Where did Ebola get its name?
Where did Ebola get its name?
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Who is Eugene Johnson?
Who is Eugene Johnson?
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How many proteins make up the Ebola virus?
How many proteins make up the Ebola virus?
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How does Ebola appear to be spread?
How does Ebola appear to be spread?
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What are the effects of Ebola?
What are the effects of Ebola?
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What symptoms did the Ebola-infected monkeys face?
What symptoms did the Ebola-infected monkeys face?
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Why is Nancy Jaax uneasy when she sees the monkeys?
Why is Nancy Jaax uneasy when she sees the monkeys?
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What is the structure of a typical virus?
What is the structure of a typical virus?
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What happened to the Ebola-infected monkeys and the healthy monkeys?
What happened to the Ebola-infected monkeys and the healthy monkeys?
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What is the slammer?
What is the slammer?
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What is the submarine?
What is the submarine?
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Why these names for the slammer and submarine?
Why these names for the slammer and submarine?
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Who is Mr. Yu G?
Who is Mr. Yu G?
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What is Ebola Sudan?
What is Ebola Sudan?
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Describe Ebola Zaire.
Describe Ebola Zaire.
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How was the disease spread through the hospital?
How was the disease spread through the hospital?
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What is the C.D.C?
What is the C.D.C?
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Who is Nurse Mayinga?
Who is Nurse Mayinga?
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What risky thing did Nurse Mayinga do?
What risky thing did Nurse Mayinga do?
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How many other people caught the virus from Nurse Mayinga?
How many other people caught the virus from Nurse Mayinga?
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What would have happened if the virus traveled through air?
What would have happened if the virus traveled through air?
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Why is the virus more like a predator?
Why is the virus more like a predator?
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What did they do at the second visit to Kitum Cave and why did they do it?
What did they do at the second visit to Kitum Cave and why did they do it?
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What is a sentinel animal?
What is a sentinel animal?
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Study Notes
Charles Monet
- Frenchman exposed to a level four virus in Kitum Cave, Africa.
Mount Elgon
- Isolated mountain on the Uganda-Kenya border with Kitum Cave.
Kitum Cave
- Located on Mount Elgon; contains level 4 viruses.
Dr. Shem Musoke
- Nairobi hospital physician infected by Monet's vomit entering his eyes.
Virus Transmission by Dr. Musoke
- Continued caring for patients while infected, facilitating virus spread.
David Silverstein
- Owner of East Africa's largest private medical practice, linked Marburg virus to patient cases.
Dr. Musoke's Infection
- Contracted the Marburg virus.
Filoviruses
- A group of thread-like viruses that resemble each other.
Ebola Zaire vs. Ebola Sudan
- Ebola Zaire is more lethal than Ebola Sudan.
Virus Hosts
- Viruses do not usually kill their natural hosts; neither monkeys nor humans can be primary hosts for the virus.
Nancy Jaax
- US Army veterinarian specializing in virus research.
USAMRIID
- Stands for United States Army Medical Research Institute for Infectious Diseases.
Ebola Name Origin
- Named after the Ebola River.
Eugene Johnson
- Civilian army scientist specializing in Ebola; oversees the USAMRIID Ebola program.
Ebola Virus Structure
- Composed of seven proteins, with limited scientific knowledge about their functions.
Ebola Transmission
- Spread via direct contact with infected bodily fluids.
Effects of Ebola
- Symptoms include rash, severe cold, immune system failure, projectile vomiting, muscle pain, and bleeding.
Symptoms in Infected Monkeys
- Silent, deranged, motionless, not eating, bleeding, dilated pupils, and facial distortion.
Nancy Jaax's Distress
- As a veterinarian, she feels uneasy upon seeing suffering animals.
Virus Structure
- Consists of a small capsule made of membranes and proteins containing DNA and RNA.
Monkey Infection Outcomes
- Infected monkeys were removed for surgery; healthy monkeys became infected through airborne transmission.
Bio-containment Facility ("The Slammer")
- Hospital designed to contain biohazard patients.
Bio-containment Morgue ("The Submarine")
- Used for patients who did not survive after being admitted to the Slammer.
Naming Purpose
- Names to alleviate patient fears and maintain public discretion.
Mr. Yu G
- First documented victim of Ebola Sudan in southern Sudan in 1976.
Characteristics of Ebola Sudan
- Originated from Maridi hospital; twice as lethal as Marburg, with a 50% fatality rate.
Characteristics of Ebola Zaire
- Emerged from Yambuku Mission Hospital; twice as deadly as Ebola Sudan.
Hospital Disease Spread
- Nurses rarely washed needles, facilitating virus transmission.
C.D.C.
- Centers for Disease Control and Prevention.
Nurse Mayinga
- Young nurse at Ngaliema Hospital who exhibited symptoms after caring for a patient.
Nurse Mayinga's Risk
- Wandered the city after showing symptoms instead of staying in the hospital.
Spread from Nurse Mayinga
- Surprisingly, no individuals contracted the virus from her.
Airborne Virus Concern
- Airborne transmission could drastically reduce the global population and increase difficulty controlling outbreaks.
Virus as Predator
- The virus has capabilities similar to a predator by potentially wiping out populations.
Kitum Cave Experiments
- Subsequent visits treated the cave as a Level 4 Hot Zone to study how bats transmit the virus to other animals.
Sentinel Animal
- An animal used to detect the virus, aiming to establish potential infection pathways in future outbreaks.
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Description
Explore the details surrounding the Marburg and Ebola viruses, their transmission, and the significant individuals involved in their outbreaks. This quiz covers key information about the Kitum Cave, virus hosts, and notable physicians like Dr. Shem Musoke and Nancy Jaax. Test your knowledge on these critical topics related to infectious diseases.