Virology Chapter 5 Practice Exam

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Questions and Answers

Viral infections are classified in all ways EXCEPT:

  • Shape
  • Size
  • Duration
  • Color (correct)

Which class of antiretrovirals is associated with a humped back, facial atrophy, and breast enlargement?

  • Protease inhibitors (correct)
  • Integrase inhibitor
  • Nucleotide reverse transcriptase inhibitors
  • Non-nucleoside reverse transcriptase inhibitors

What cells are responsible for the immune response in the body?

  • CD4 (correct)
  • Protease
  • T
  • Virion

Which of the following medications is a prodrug?

<p>Famciclovir (D)</p> Signup and view all the answers

Which of the following medications can be used for the treatment or prevention of influenza A and B?

<p>Oseltamivir (B)</p> Signup and view all the answers

Which of the following non-nucleoside reverse transcriptase inhibitors should be taken with a high-fat meal?

<p>Rilpivirine (D)</p> Signup and view all the answers

Why is it more difficult to develop antiviral drugs than it is to develop antibiotics?

<p>Viruses utilize the host cell processes, so killing them is often toxic to the patient. (B)</p> Signup and view all the answers

Which of the following nucleoside reverse transcriptase inhibitors is available in an injectable dosage form?

<p>Zidovudine (A)</p> Signup and view all the answers

Which of the following was one of the first drugs developed specifically for the treatment of HIV?

<p>Zidovudine (D)</p> Signup and view all the answers

What medication is a fusion inhibitor?

<p>Enfuvirtide (B)</p> Signup and view all the answers

Prior to administering a flu shot, it is important to confirm that the patient is not allergic to:

<p>Eggs (C)</p> Signup and view all the answers

Zidovudine:

<p>Is recommended for prevention of HIV after a needle stick (D)</p> Signup and view all the answers

Which of the following drugs is a fusion inhibitor, acting by preventing the HIV virus from entering immune cells?

<p>Enfuvirtide (B)</p> Signup and view all the answers

Ritonavir:

<p>Two of the above are correct (C)</p> Signup and view all the answers

Drug classes used to treat retroviruses include:

<p>All of the answers are correct (B)</p> Signup and view all the answers

What is a prodrug?

<p>A compound that becomes an active drug upon administration (A)</p> Signup and view all the answers

Which of the following drugs is not an NNRTI?

<p>Enfuvirtide (C)</p> Signup and view all the answers

What is a viral inflammation of the liver?

<p>Hepatitis (D)</p> Signup and view all the answers

Which of the following should a pharmacy technician do when dispensing Epzicom?

<p>Make sure the patient receives a manufacturer's card that he/she will carry at all times (C)</p> Signup and view all the answers

Which of the following settings are approved for administration of vaccines?

<p>All of the answers are correct (C)</p> Signup and view all the answers

All of the following complementary and alternative therapy have been associated with the reduction of viral infection EXCEPT:

<p>St. John's Wort (A)</p> Signup and view all the answers

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Study Notes

Viral Infections and Antiviral Medications

  • Viral infections can be classified based on shape, duration, and size, but not color.
  • Protease inhibitors are associated with side effects like a humped back and facial atrophy.

Immune Response and Cells

  • CD4 T cells play a crucial role in the immune response.
  • Various medications exist for treating viral infections, including prodrugs like famciclovir.

Flu Medications

  • Oseltamivir is used for treating and preventing influenza A and B.
  • Rilpivirine, a non-nucleoside reverse transcriptase inhibitor, is taken with high-fat meals.

Drug Development Challenges

  • Developing antiviral drugs is challenging due to the need to avoid toxicity to host cells having similar processes as viruses.

Injectable and Early HIV Treatments

  • Zidovudine is available in injectable form and was one of the first drugs for HIV treatment.

Fusion Inhibitors

  • Enfuvirtide acts as a fusion inhibitor, preventing HIV from entering immune cells.

Allergies and Vaccinations

  • Prior to flu shots, check for allergies to eggs.
  • Zidovudine is abbreviated as AZT and is recommended for post-exposure prevention of HIV.

Drug Classifications

  • Classes for treating retroviruses include nucleoside, non-nucleoside reverse transcriptase inhibitors, and protease inhibitors.
  • A prodrug becomes an active drug upon administration.

Non-NNRTI Drugs

  • Enfuvirtide is not classified as a non-nucleoside reverse transcriptase inhibitor.

Viral Hepatitis

  • Hepatitis is defined as a viral inflammation of the liver.

Pharmacy Protocols

  • When dispensing Epzicom, provide a manufacturer's card to the patient.
  • Vaccines can be administered in various settings, including doctor’s offices, travel clinics, and pharmacies.

Complementary Therapies

  • St. John's Wort has not shown a correlation with viral infection reduction.

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