Podcast
Questions and Answers
What is the role of acidic pH in uncoating of viruses?
What is the role of acidic pH in uncoating of viruses?
Acidic pH in the endosome is required for uncoating of viruses.
Why is dissolution of the infecting agent an obligatory step for viruses?
Why is dissolution of the infecting agent an obligatory step for viruses?
Viruses are the only infectious agents for which dissolution of the infecting agent is an obligatory step in the replicative pathway.
What is the first step in viral gene expression?
What is the first step in viral gene expression?
The first step in viral gene expression is mRNA synthesis.
Where are viral proteins synthesized in the cell?
Where are viral proteins synthesized in the cell?
What happens to many viral proteins after synthesis?
What happens to many viral proteins after synthesis?
Where is viral DNA usually replicated?
Where is viral DNA usually replicated?
What is the first event of the viral growth cycle?
What is the first event of the viral growth cycle?
What continues to function and accumulate within the cell during the eclipse period?
What continues to function and accumulate within the cell during the eclipse period?
How is the eclipse period defined?
How is the eclipse period defined?
What is the latent period defined as?
What is the latent period defined as?
What type of replication is unique to viruses?
What type of replication is unique to viruses?
What is the cytopathic effect (CPE) and when does it culminate?
What is the cytopathic effect (CPE) and when does it culminate?
What is the difference between lytic and lysogenic cycle in virus replication?
What is the difference between lytic and lysogenic cycle in virus replication?
Which bacteriophage infects E.coli in the human intestinal tract?
Which bacteriophage infects E.coli in the human intestinal tract?
When is antiviral therapy recommended?
When is antiviral therapy recommended?
What is the role of nucleoside and nucleotide analogs in antiviral chemotherapy?
What is the role of nucleoside and nucleotide analogs in antiviral chemotherapy?
Under what conditions do lysogenic phages become active?
Under what conditions do lysogenic phages become active?
Why are lytic phages more suitable for phage therapy?
Why are lytic phages more suitable for phage therapy?
Where do poxviruses replicate?
Where do poxviruses replicate?
What is the genome of all DNA viruses composed of?
What is the genome of all DNA viruses composed of?
Where is viral genomic RNA generally duplicated?
Where is viral genomic RNA generally duplicated?
Where is the mRNA of hepatitis delta virus synthesized?
Where is the mRNA of hepatitis delta virus synthesized?
What is gene expression?
What is gene expression?
What is maturation in the context of viral replication?
What is maturation in the context of viral replication?
What is the main action of Protease Inhibitors (PI) on HIV virion?
What is the main action of Protease Inhibitors (PI) on HIV virion?
Which was the first protease inhibitor approved for the treatment of HIV infection?
Which was the first protease inhibitor approved for the treatment of HIV infection?
What is the main action of Fuzeon in the context of HIV-1 infection?
What is the main action of Fuzeon in the context of HIV-1 infection?
How do Amantadine and Rimantadine exert their antiviral effect on influenza A viruses?
How do Amantadine and Rimantadine exert their antiviral effect on influenza A viruses?
What is the mechanism of action of Foscarnet as an antiviral agent?
What is the mechanism of action of Foscarnet as an antiviral agent?
What was the historical significance of Methisazone as an antiviral agent?
What was the historical significance of Methisazone as an antiviral agent?
What are the early events in the viral growth cycle during the Initiation Phase?
What are the early events in the viral growth cycle during the Initiation Phase?
What is the first step in viral infection, involving the interaction of a virion with a specific receptor site on the cell's surface?
What is the first step in viral infection, involving the interaction of a virion with a specific receptor site on the cell's surface?
What is the process where the virus particle is taken up inside the cell after binding to the cell's surface?
What is the process where the virus particle is taken up inside the cell after binding to the cell's surface?
What are the middle events in the viral growth cycle, involving gene expression and genome replication?
What are the middle events in the viral growth cycle, involving gene expression and genome replication?
What are the late events in the viral growth cycle, involving assembly and release of new virions?
What are the late events in the viral growth cycle, involving assembly and release of new virions?
What determines the susceptibility of a cell to a virus based on the presence or absence of specific molecules on the cell's surface?
What determines the susceptibility of a cell to a virus based on the presence or absence of specific molecules on the cell's surface?
Which cycle involves the fusion of the nucleic acid of a bacteriophage with DNA of a host?
Which cycle involves the fusion of the nucleic acid of a bacteriophage with DNA of a host?
What is the lytic bacteriophage that infects E.coli found in the human intestinal tract?
What is the lytic bacteriophage that infects E.coli found in the human intestinal tract?
When is antiviral therapy recommended?
When is antiviral therapy recommended?
What is the main classification of available antiviral agents?
What is the main classification of available antiviral agents?
What is the main purpose of gene expression in viruses?
What is the main purpose of gene expression in viruses?
Describe the process of maturation in viral replication.
Describe the process of maturation in viral replication.
Why are lysogenic phages considered to be active when host conditions deteriorate or become stressful?
Why are lysogenic phages considered to be active when host conditions deteriorate or become stressful?
What is the primary target of nucleoside analogs in antiviral chemotherapy?
What is the primary target of nucleoside analogs in antiviral chemotherapy?
Explain the difference between release of naked viruses and budding viruses during the viral replication cycle.
Explain the difference between release of naked viruses and budding viruses during the viral replication cycle.
Where does the mRNA of hepatitis delta virus get synthesized?
Where does the mRNA of hepatitis delta virus get synthesized?
What distinguishes parvoviruses from other DNA viruses in terms of their genome composition?
What distinguishes parvoviruses from other DNA viruses in terms of their genome composition?
Why do poxviruses carry their own polymerase within the virus particle?
Why do poxviruses carry their own polymerase within the virus particle?
What are interferons (IFNs) and why are they produced quickly in response to viral infection?
What are interferons (IFNs) and why are they produced quickly in response to viral infection?
How do interferons (IFNs) inhibit viral replication at the molecular level?
How do interferons (IFNs) inhibit viral replication at the molecular level?
What are the three general groups of interferons (IFNs) and which group is mainly produced by lymphocytes such as T cells and natural killer (NK) cells?
What are the three general groups of interferons (IFNs) and which group is mainly produced by lymphocytes such as T cells and natural killer (NK) cells?
How are RNA viruses different from DNA viruses in terms of inducing interferons (IFNs)?
How are RNA viruses different from DNA viruses in terms of inducing interferons (IFNs)?
What is the significance of interferons (IFNs) inducing the synthesis of other proteins in the host cell?
What is the significance of interferons (IFNs) inducing the synthesis of other proteins in the host cell?
In the context of viral infections, how do interferons (IFNs) enhance the major histocompatibility complex (MHC) expression?
In the context of viral infections, how do interferons (IFNs) enhance the major histocompatibility complex (MHC) expression?
What is the mechanism of action of Protease Inhibitors (PI) on HIV virion?
What is the mechanism of action of Protease Inhibitors (PI) on HIV virion?
How do Amantadine and Rimantadine exert their antiviral effect on influenza A viruses?
How do Amantadine and Rimantadine exert their antiviral effect on influenza A viruses?
What is the main action of Fuzeon in the context of HIV-1 infection?
What is the main action of Fuzeon in the context of HIV-1 infection?
How does Foscarnet selectively inhibit viral DNA polymerases and reverse transcriptases?
How does Foscarnet selectively inhibit viral DNA polymerases and reverse transcriptases?
What historical role did Methisazone play as an antiviral agent?
What historical role did Methisazone play as an antiviral agent?
What is the specific target of Protease Inhibitors (PI) within the HIV protease enzyme?
What is the specific target of Protease Inhibitors (PI) within the HIV protease enzyme?
