Viral Infections Overview

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Questions and Answers

What is a common cause of acute atrophic candidiasis?

  • Prolonged use of antibiotics or corticosteroids (correct)
  • Vitamin deficiency
  • Poor oral hygiene practices
  • Infection from dental procedures

What characteristic differentiates chronic atrophic candidiasis from acute atrophic candidiasis?

  • It occurs exclusively in young individuals
  • Presence of a pseudomembrane
  • It only affects the lower dental arch
  • It is usually asymptomatic (correct)

In which area is chronic atrophic candidiasis most frequently found?

  • Under orthodontic appliances
  • In the buccal mucosa
  • Under upper dentures (correct)
  • On the tongue

What feature is indicative of acute atrophic candidiasis histopathology?

<p>Thin atrophic non-keratinized epithelium (D)</p> Signup and view all the answers

Which feature is most likely seen in the histopathology of chronic atrophic candidiasis?

<p>Chronic inflammatory cells infiltrating both epithelium and connective tissue (B)</p> Signup and view all the answers

What is hairy leukoplakia most commonly associated with?

<p>Epstein-Barr Virus (EBV) (C)</p> Signup and view all the answers

Which histological feature is characterized by swollen cells with specific nuclei in hairy leukoplakia?

<p>Balloon cells (D)</p> Signup and view all the answers

How does hairy leukoplakia typically present on the tongue?

<p>Non-removable white patches (D)</p> Signup and view all the answers

What is the significance of demonstrating EBV in patients with hairy leukoplakia?

<p>It is essential for diagnosis (A)</p> Signup and view all the answers

Which statement is true regarding the inflammatory response in hairy leukoplakia?

<p>There is an absence of inflammatory cells (C)</p> Signup and view all the answers

Which type of CMC candidiasis typically presents within the first five years of life and involves severe oral candidiasis and severe skin involvement?

<p>Diffuse CMC candidiasis (A)</p> Signup and view all the answers

What is a characteristic endocrine symptom of Candidiosis endocrinopathy syndrome?

<p>Hypothyroidism (D)</p> Signup and view all the answers

What is a common oral manifestation associated with congenital syphilis?

<p>Hutchinson incisors (B), Moon's molars (D)</p> Signup and view all the answers

Which condition is associated with the formation of granulomas in the oral cavity?

<p>Tuberculosis (B)</p> Signup and view all the answers

Which CMC candidiasis type is inherited as autosomal recessive?

<p>Familial CMC candidiasis (C)</p> Signup and view all the answers

What is the characteristic appearance of Moon's molars in congenital syphilis?

<p>Defective cusps and hypoplastic occlusal surface (B)</p> Signup and view all the answers

Which oral manifestation is most commonly associated with HIV infection?

<p>Candidiasis (D)</p> Signup and view all the answers

What is a common mode of transmission for HIV infection?

<p>Blood and body fluids (A)</p> Signup and view all the answers

Which test is NOT typically used for diagnosing tuberculosis?

<p>Serological test for antibodies (D)</p> Signup and view all the answers

Which of the following is typically seen as a chronic oral candidiasis symptom in Candidiosis endocrinopathy syndrome?

<p>Chronic oral candidiasis (C)</p> Signup and view all the answers

What type of leprosy shows predominant cell-mediated immunity?

<p>Tuberculoid leprosy (A)</p> Signup and view all the answers

Which oral lesion is primarily associated with pulmonary tuberculosis?

<p>Chronic ulcer covered by grayish-yellow slough (C)</p> Signup and view all the answers

Late onset CMC is characterized by its mild nature and primarily affects which area?

<p>Oral mucosa (A)</p> Signup and view all the answers

Which group of lesions is strongly associated with HIV infection?

<p>Candidiasis (C)</p> Signup and view all the answers

What unique feature identifies Langhans cells in tuberculosis granulomas?

<p>Horseshoe arrangement of nuclei (D)</p> Signup and view all the answers

Which of the following conditions is known to have a rare occurrence of oral cancer associated with it?

<p>Tertiary syphilis (A)</p> Signup and view all the answers

What is the primary causative virus of herpetic stomatitis?

<p>Herpes simplex virus type 1 (A)</p> Signup and view all the answers

Which of the following conditions is characterized by vesicular eruptions along the distribution of sensory nerves?

<p>Herpes zoster (B)</p> Signup and view all the answers

What triggers the reactivation of the varicella-zoster virus in herpes zoster?

<p>Emotional stress (D)</p> Signup and view all the answers

Which oral finding is most characteristic of infectious mononucleosis?

<p>Petechial hemorrhage (C)</p> Signup and view all the answers

What is a common symptom of primary herpes simplex virus infection in children?

<p>Fever and malaise (C)</p> Signup and view all the answers

In herpes labialis, which symptoms commonly precede the vesicular lesions?

<p>Numbness and itching (B)</p> Signup and view all the answers

What distinguishes herpangina from primary herpes simplex infection?

<p>Location of vesicles and ulcers (B)</p> Signup and view all the answers

What is the incubation period for herpetic gingivostomatitis?

<p>5 days (A)</p> Signup and view all the answers

Which virus is associated with hairy leukoplakia?

<p>Epstein-Barr virus (C)</p> Signup and view all the answers

Which of the following is a common complication of herpes zoster?

<p>Post herpetic neuralgia (C)</p> Signup and view all the answers

Which virus causes hand, foot, and mouth disease?

<p>Coxsackie virus A (A)</p> Signup and view all the answers

What are Koplik's spots most commonly associated with?

<p>Measles (C)</p> Signup and view all the answers

What typically causes the vesicular ulcers in chickenpox?

<p>Virus replication in mucosal epithelium (C)</p> Signup and view all the answers

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Study Notes

Viral Infections

  • Herpetic stomatitis is the most common viral infection of the mouth and is mainly caused by Herpes Simplex Virus type 1 (HSV-1).
  • Herpetic gingivostomatitis is a primary infection, mostly seen in children and young adults.
  • The incubation period for herpetic gingivostomatitis is 5 days, during which patients experience fever, malaise, numerous small vesicles on the oral mucosa, and regional lymphadenitis.
  • Recurrent herpes infections occur in 1/3 of those who have had a primary infection and are characterized by localized symptoms without systemic illness.
  • The most common form of recurrent herpes is herpes labialis.
  • Herpes zoster is the recurrent form of chickenpox.
  • Herpangina is caused by Coxsackie A virus and presents with fever, malaise, anorexia, and sore throat with vesicles on the palate, tonsils, and uvula that rupture leaving small ulcers.
  • Hand, foot, and mouth disease is caused by coxsackie virus A and presents with small ulcers on the gingiva, tongue, palate, buccal mucosa, palms of the hands, and soles of the feet.
  • Infectious mononucleosis (glandular fever) is caused by Epstein-Barr virus (EBV) and presents with fever, pharyngitis, enlarged lymph nodes, and long-lasting malaise.
  • Measles is a viral infection that is more severe in developing countries and presents with Koplik's spots which are pin-point bluish-white spots against an erythematous background found on the buccal mucosa opposite the molar teeth.
  • Hairy Leukoplakia is caused by EBV and presents as non-removable white patches on the lateral borders of the tongue, usually bilaterally.

Bacterial Infections

  • Syphilis occurs in three stages: primary syphilis, secondary syphilis, and tertiary syphilis.
  • Tertiary syphilis is rare but can lead to oral lesions, such as syphilitic leukoplakia.
  • Tuberculosis is caused by Mycobacterium tuberculosis and can lead to oral lesions, such as chronic, painless undermined ulcers.

Fungal Infections

  • Oral candidiasis is a common fungal infection that can occur in both a chronic and acute form.
  • Acute atrophic (erythematous) candidiasis presents as red, often painful areas, resembling thrush but without the pseudomembrane.
  • Chronic atrophic candidiasis (denture stomatitis) is commonly found in denture wearers and is characterized by erythema and edema of the covered mucosa.
  • Candidiasis can also be associated with immune deficiencies, such as HIV infection.
  • Deep visceral mycosis is a rare fungal infection that can affect the oral mucosa and is often associated with immune deficiency.

HIV Infection

  • HIV infection is a viral infection that can lead to AIDS, a condition characterized by opportunistic infections and cancers.
  • Oral manifestations of HIV infection can be categorized into three groups:
  • Group 1: Lesions strongly associated with HIV infection, such as candidiasis, hairy leukoplakia, and HIV-associated periodontal diseases.
  • Group 2: Lesions commonly associated with HIV infection, such as atypical ulceration, idiopathic thrombocytopenic purpura, and salivary gland disorders.
  • Group 3: Lesions possibly associated with HIV infection, such as bacterial infections, fungal infections, melanotic hyperpigmentation, and neurological disturbances.
  • HIV gingivitis (linear gingival erythema) is a characteristic finding in HIV infection and presents as a band of erythema along the gingival margin.

Other

  • Ramsy Hunt syndrome is caused by herpes zoster and affects the facial and auditory nerves, leading to facial paralysis, painful vesicular eruptions, tinnitus, deafness, vertigo, and loss of taste sensation.
  • Congenital syphilis is a condition that presents with various symptoms, including dental defects, eighth nerve defect, ocular keratitis, saddle nose, and other bone and organ defects.

Histopathology

  • Histopathology is a valuable tool for diagnosing oral infections, as it allows for the identification of specific characteristics of the infecting organism and the host response.
  • Granulomas are often found in tuberculosis, with characteristically arranged multinucleated giant cells known as Langhans cells.

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