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Questions and Answers
Which type of fusion protein tends to form dimers and involves rearrangement of multimers of protein subunits?
Which type of fusion protein tends to form dimers and involves rearrangement of multimers of protein subunits?
- Type I fusion proteins
- Class III fusion proteins
- Class II fusion proteins (correct)
- Class I fusion proteins
What type of conformational changes reveal a fusion peptide, which gets inserted into the target cellular membrane during virus-induced membrane fusion?
What type of conformational changes reveal a fusion peptide, which gets inserted into the target cellular membrane during virus-induced membrane fusion?
- Conformational changes that reveal a fusion peptide (correct)
- Conformational changes after fusion
- Conformational changes due to ATP presence
- Conformational changes during ER maturation
Which type of fusion protein tends to be mostly alpha-helical and forms trimers with two distinct conformations?
Which type of fusion protein tends to be mostly alpha-helical and forms trimers with two distinct conformations?
- Type I fusion proteins
- Class III fusion proteins
- Class II fusion proteins
- Class I fusion proteins (correct)
Where are fusion proteins synthesized, folded, and assembled before undergoing maturation?
Where are fusion proteins synthesized, folded, and assembled before undergoing maturation?
Which cellular machinery is often utilized by viruses for transportation to the cytosol?
Which cellular machinery is often utilized by viruses for transportation to the cytosol?
What is a strategy used by viruses to pass through the nuclear membrane?
What is a strategy used by viruses to pass through the nuclear membrane?
What is a strategy for preventing virus entry?
What is a strategy for preventing virus entry?
Which type of virus uses the nucleus as a site of replication, taking advantage of the cellular machinery for transcription?
Which type of virus uses the nucleus as a site of replication, taking advantage of the cellular machinery for transcription?
What is the order of genes in coronaviruses based on genome homologies?
What is the order of genes in coronaviruses based on genome homologies?
What type of RNA genome do coronaviruses possess?
What type of RNA genome do coronaviruses possess?
Where are the fusion proteins synthesized, folded, and assembled before undergoing maturation?
Where are the fusion proteins synthesized, folded, and assembled before undergoing maturation?
What is the function of importins in virus entry into the nucleus?
What is the function of importins in virus entry into the nucleus?
What is the role of hydrophobic proteins in capsids during virus entry?
What is the role of hydrophobic proteins in capsids during virus entry?
What is the primary function of neutralizing antibodies in preventing virus entry?
What is the primary function of neutralizing antibodies in preventing virus entry?
What is the advantage of narrow spectrum antivirals?
What is the advantage of narrow spectrum antivirals?
What is the structure of coronaviruses?
What is the structure of coronaviruses?
Which type of fusion protein mostly consists of alpha-helices and tends to form trimers?
Which type of fusion protein mostly consists of alpha-helices and tends to form trimers?
What type of conformational changes reveal a fusion peptide, which gets inserted into the target cellular membrane during virus-induced membrane fusion?
What type of conformational changes reveal a fusion peptide, which gets inserted into the target cellular membrane during virus-induced membrane fusion?
Where are fusion proteins synthesized, folded, and assembled before undergoing maturation?
Where are fusion proteins synthesized, folded, and assembled before undergoing maturation?
Which type of fusion protein tends to form dimers and involves rearrangement of multimers of protein subunits?
Which type of fusion protein tends to form dimers and involves rearrangement of multimers of protein subunits?
What is the general characteristic of Class II fusion proteins?
What is the general characteristic of Class II fusion proteins?
What type of energy is not needed for viral membrane fusion due to the conformation changes that occur?
What type of energy is not needed for viral membrane fusion due to the conformation changes that occur?
What triggers the rearrangement of multimers of protein subunits in Class II fusion proteins before the final trimer is formed?
What triggers the rearrangement of multimers of protein subunits in Class II fusion proteins before the final trimer is formed?
What role do fusion proteins play in viral infection?
What role do fusion proteins play in viral infection?
What is the characteristic conformation of Class I fusion proteins after fusion?
What is the characteristic conformation of Class I fusion proteins after fusion?
What is the primary structure of Class III fusion proteins?
What is the primary structure of Class III fusion proteins?
How are fusion proteins cleaved while transiting from the ER-Golgi to the plasma membrane?
How are fusion proteins cleaved while transiting from the ER-Golgi to the plasma membrane?
What happens to the fusion peptide during virus-induced membrane fusion?
What happens to the fusion peptide during virus-induced membrane fusion?
Which type of fusion proteins can create membrane channels followed by genome egress?
Which type of fusion proteins can create membrane channels followed by genome egress?
What is a strategy used by some viruses to pass through the nuclear membrane?
What is a strategy used by some viruses to pass through the nuclear membrane?
What is the primary function of narrow spectrum antivirals?
What is the primary function of narrow spectrum antivirals?
What is the order of genes in coronaviruses based on genome homologies?
What is the order of genes in coronaviruses based on genome homologies?
What is the structure of coronaviruses?
What is the structure of coronaviruses?
What is the primary structure of Class III fusion proteins?
What is the primary structure of Class III fusion proteins?
What is the role of hydrophobic proteins in capsids during virus entry?
What is the role of hydrophobic proteins in capsids during virus entry?
What is the function of importins in virus entry into the nucleus?
What is the function of importins in virus entry into the nucleus?
What is the general characteristic of Class II fusion proteins?
What is the general characteristic of Class II fusion proteins?
What type of RNA genome do coronaviruses possess?
What type of RNA genome do coronaviruses possess?
What happens to the fusion peptide during virus-induced membrane fusion?
What happens to the fusion peptide during virus-induced membrane fusion?
Where are fusion proteins synthesized, folded, and assembled before undergoing maturation?
Where are fusion proteins synthesized, folded, and assembled before undergoing maturation?
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