Podcast
Questions and Answers
Which cellular process is NOT essential for virus internalization/penetration?
Which cellular process is NOT essential for virus internalization/penetration?
- Carboxylic ionophores
- Preventing endosome acidification
- Inhibiting cytoplasmic protein synthesis (correct)
- Using lysosomotropic agents
What is a strategy for some viruses to pass through the nuclear membrane?
What is a strategy for some viruses to pass through the nuclear membrane?
- Directly fusing with the nuclear membrane
- Interacting with importins and nuclear localization signals (correct)
- Inducing nuclear pore disassembly
- Utilizing lysosomotropic agents
Which type of viruses typically use the nucleus as a site of replication?
Which type of viruses typically use the nucleus as a site of replication?
- Retroviruses
- RNA viruses
- DNA viruses (correct)
- Enveloped viruses
What is the function of neutralizing antibodies in preventing virus entry?
What is the function of neutralizing antibodies in preventing virus entry?
Which type of antiviral drugs target a specific virus or a small range of viruses?
Which type of antiviral drugs target a specific virus or a small range of viruses?
What is the primary structure of coronaviruses?
What is the primary structure of coronaviruses?
What is the function of the trimeric spikes on coronaviruses?
What is the function of the trimeric spikes on coronaviruses?
Which cellular machinery is essential for DNA virus replication in the nucleus?
Which cellular machinery is essential for DNA virus replication in the nucleus?
What is the role of importins in virus entry into the nucleus?
What is the role of importins in virus entry into the nucleus?
Which type of antiviral drugs target a wide range of viruses?
Which type of antiviral drugs target a wide range of viruses?
What is the primary structure of the viral genome of coronaviruses?
What is the primary structure of the viral genome of coronaviruses?
What is the role of the 5’ terminal cap and 3’ poly (A) tail in the viral genome of coronaviruses?
What is the role of the 5’ terminal cap and 3’ poly (A) tail in the viral genome of coronaviruses?
Which type of proteins are generally involved in mediating membrane fusion in viral infections?
Which type of proteins are generally involved in mediating membrane fusion in viral infections?
What is the role of cellular proteases in the maturation of fusion proteins?
What is the role of cellular proteases in the maturation of fusion proteins?
What happens to the fusion peptide during virus-induced membrane fusion?
What happens to the fusion peptide during virus-induced membrane fusion?
Which type of fusion proteins mostly tend to form trimers and have two distinct conformations perpendicular to the envelope surface and hairpin conformation after fusion?
Which type of fusion proteins mostly tend to form trimers and have two distinct conformations perpendicular to the envelope surface and hairpin conformation after fusion?
What type of fusion proteins involve rearrangement of multimers of protein subunits but only minor conformational changes at the tertiary level?
What type of fusion proteins involve rearrangement of multimers of protein subunits but only minor conformational changes at the tertiary level?
Which type of fusion proteins generally consist of two subunits: fusion subunit and receptor binding subunit?
Which type of fusion proteins generally consist of two subunits: fusion subunit and receptor binding subunit?
What provides the energy for membrane fusion mediated by viral fusion proteins?
What provides the energy for membrane fusion mediated by viral fusion proteins?
What is the main role of fusion proteins in viral infection?
What is the main role of fusion proteins in viral infection?
What is the primary triggering event for fusion involving Class II fusion proteins?
What is the primary triggering event for fusion involving Class II fusion proteins?
What type of fusion proteins are mostly alpha-helical and tend to form trimers?
What type of fusion proteins are mostly alpha-helical and tend to form trimers?
What is the characteristic structure of Class II fusion proteins?
What is the characteristic structure of Class II fusion proteins?
What type of fusion proteins involve conformational changes that reveal a fusion peptide inserted into the target cellular membrane during virus-induced membrane fusion?
What type of fusion proteins involve conformational changes that reveal a fusion peptide inserted into the target cellular membrane during virus-induced membrane fusion?
