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Questions and Answers
Quante tempore dura acute dermatose?
Quante tempore dura acute dermatose?
Dies a septimanas
Que es le causa de urticaria?
Que es le causa de urticaria?
Erythema multiforme es un reaction de hypersensitivitate a certe drogas e infectiones.
Erythema multiforme es un reaction de hypersensitivitate a certe drogas e infectiones.
True
Qual es un sintoma commun de angioedema?
Qual es un sintoma commun de angioedema?
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Que es le range de etates pro le occurrencia de angioedema?
Que es le range de etates pro le occurrencia de angioedema?
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Que son le duo tipos de hypersensibilitate associate con angioedema?
Que son le duo tipos de hypersensibilitate associate con angioedema?
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Que es le characteristica histologic de acute dermatose?
Que es le characteristica histologic de acute dermatose?
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Que es le duration de un wheal?
Que es le duration de un wheal?
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Que es un complication potential de acute dermatose?
Que es un complication potential de acute dermatose?
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Que es le duo typos principal de tractamento pro acute dermatose?
Que es le duo typos principal de tractamento pro acute dermatose?
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Quante tempore dura chronic dermatose?
Quante tempore dura chronic dermatose?
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Le alterationes in le crescimento epidermal es un characteristic de chronic dermatose.
Le alterationes in le crescimento epidermal es un characteristic de chronic dermatose.
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Que causa le facie rugosa in chronic dermatose?
Que causa le facie rugosa in chronic dermatose?
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Le ichthyoses hereditari es characterisate per un desquamation deficiente.
Le ichthyoses hereditari es characterisate per un desquamation deficiente.
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Quante tempore dura lichen planus?
Quante tempore dura lichen planus?
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Que es un factor de risco pro le disveloppamento de carcinoma squamous cellular in patientes con lichen planus lingual?
Que es un factor de risco pro le disveloppamento de carcinoma squamous cellular in patientes con lichen planus lingual?
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Qual es le characteristic histologic de seborrheic dermatitis?
Qual es le characteristic histologic de seborrheic dermatitis?
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Quale del sequente conditiones es associate con le presentia de scale?
Quale del sequente conditiones es associate con le presentia de scale?
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Psoriasis es un condition autoimmune.
Psoriasis es un condition autoimmune.
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Quale allele HLA es associate con psoriasis?
Quale allele HLA es associate con psoriasis?
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Que es un sintoma commun de psoriasis?
Que es un sintoma commun de psoriasis?
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Que es le location del glandulas sebaceous de alte densitate?
Que es le location del glandulas sebaceous de alte densitate?
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Quale del sequente es un sintoma de psoriasis?
Quale del sequente es un sintoma de psoriasis?
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Que es le signification del signo de Auspitz?
Que es le signification del signo de Auspitz?
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Le infection de HIV pote resultar in un augmento del secretion de sebo.
Le infection de HIV pote resultar in un augmento del secretion de sebo.
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Que es le characteristica histologic de lichen planus?
Que es le characteristica histologic de lichen planus?
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Le junction dermoepidermal es typicmente normal in lichen planus.
Le junction dermoepidermal es typicmente normal in lichen planus.
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Que es un characteristica histologic de psoriasis?
Que es un characteristica histologic de psoriasis?
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Quale del sequente es un tractamento pro psoriasis?
Quale del sequente es un tractamento pro psoriasis?
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Que es le signification de "PUVA"?
Que es le signification de "PUVA"?
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Study Notes
Acute Dermatoses
- Acute dermatoses last from days to weeks.
- Characterized by inflammatory infiltrate and edema.
- Epidermal, vascular, and subcutaneous layers are impacted.
- Urticaria involves degranulation of mast cells, producing dermal microvascular hyperpermeability.
- Lesions include pruritic, edematous plaques (wheals), initial erythema, pruritus, red papulovesicular lesions, oozing rash, crusted lesions, vesicles, bullae, etc.
- Associated with acute conditions, such as age under 6 weeks, angioedema (complement-mediated), and conditions that cause pressure development.
- Pathophysiology involves antigen-induced release of vasoactive mediators from mast cells, Type 1 hypersensitivity, drug reactions, and C1 deficiency.
Chronic Dermatoses
- Chronic dermatoses persist for months to years.
- Changes include epidermal growth and dermal fibrosis.
- Skin surface is roughened due to excessive scaling and shedding.
- Hereditary ichthyoses involve extensive scaling due to defects in desquamation.
- Associated with conditions such as age (over 6 weeks), angioedema, and pressure development.
Associated Diseases and Conditions
- Dermatoses are associated with various conditions including age, angioedema, asthma, allergic rhinitis, certain infections (including HSV, Mycoplasma, Histoplasmosis, coccidioidomycosis, typhoid, and leprosy), drug reactions (sulfonamides, penicillin, barbiturates, salicylates, hydantoins, and antimalarials), cancers like carcinoma and lymphoma, and collagen vascular disorders (SLE, dermatomyositis, and polyarteritis nodosa).
Histological Findings
- Histological examination reveals various inflammatory cell types, alterations in the epidermis, and involvement of the dermoepidermal junction.
- Inclusions like Civatte bodies might be present in some conditions.
- In chronic conditions, features such as hypergranulosis, hyperkeratosis, and degeneration of basal cells may be observed during examination.
Treatment Approaches
- Treatment options include the use of antihistamines, systemic corticosteroids, omalizumab, topical steroids, anti-TNF agents, UVA, corticosteroids, and PUVA.
- Topical antifungals and glucocorticoids are used for specific conditions.
Specific Dermatoses
- Erythema multiforme: Hypersensitivity reaction to drugs or infections, impacting epidermal cells immunologically.
- Stevens-Johnson syndrome: Severe hypersensitivity reaction involving the skin and mucous membranes.
- Allergic contact dermatitis: Type 4 hypersensitivity reaction.
- Atopic dermatitis (eczema): A chronic inflammatory condition.
- Drug-related dermatitis: Reacts to certain medication.
- Photoeczematous dermatitis: Reaction to UV exposure.
- Primary irritant dermatitis: reaction to external substances (irritants).
- Acute graft vs. host disease: Occurs after transplantation.
- Fixed drug eruptions: Reaction at fixed sites of skin following repeated drug contact.
- Pustular psoriasis: Characterized by pustules on erythematous skin.
- Lichen planus: Inflammatory skin condition.
- Psoriasis: Autoimmune condition, characterized by skin plaques.
Additional Findings
- Other findings include high density sebaceous glands in certain areas, lesions like erythema, plaques, various types of pustules, itching, scaling, and variations in pigmentation.
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