Veterinary Blood Chemistry Panel

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Blood chemistry panels/profiles assess the function of internal organs, identify endocrine levels, cholesterol, electrolytes and more. For example, if a blood test shows a deficiency in albumin levels, then a vet knows to examine a dogs ____ because albumin is produced here

  • Kidneys
  • Pancreas
  • Liver (correct)
  • Gallbladder

High levels indicate stress, Cushing's dz, diabetes, pancreatitis, or can be due to certain medications. Low levels can indicate liver disease, insulin overdose, severe bacterial infection, hypothyroidism or Addison's dz

  • GLU (glucose) (correct)
  • BUN (blood urea nitrogen)/ CREA (creatinine)
  • PHOS (phosphorus)
  • CA (calcium)

High levels may indicate kidney failure or dz, poor circulation to the kidneys and urinary obstruction. But it may indicate dehydration or indicate high protein diet only (usually dogs fed a raw meat diet may have a higher level). Low levels may indicate liver dz or starvation

  • GLU (glucose)
  • BUN (blood urea nitrogen)/ CREA (creatinine) (correct)
  • PHOS (phosphorus)
  • CA (calcium)

High levels indicate kidney dz, dietary imbalance, excess ingestion of Vit D and severe tissue trauma. Low levels may indicate dietary imbalance, certain cancers, overdose of insulin, diabetes, eclampsia and an overactive parathyroid gland

<p>C) PHOS (phosphorus) (C)</p> Signup and view all the answers

High levels indicate certain forms of cancer, Addison's dz, excess intake of Vit D and an overactive parathyroid gland. Low levels indicate eclampsia, severe pancreatitis, dietary imbalance, intestinal absorption disorders, low intake of Vit D, Cushing's dz and certain toxin ingestions

<p>PHOS (phosphorus) (C)</p> Signup and view all the answers

High levels indicate dehydration, inflammation, chronic infection and certain cancers. Low levels indicate intestinal absorption problems, liver dz, Addison's dz, severe burns and losses through the kidneys

<p>TP (total protein) (A)</p> Signup and view all the answers

High levels indicate dehydration. Low levels indicate chronic inflammation, liver dz, kidney dz, starvation, and blood loss

<p>ALB (albumin) (B)</p> Signup and view all the answers

High levels may indicate liver damage, toxin ingestion, Cushing's dz and various metabolic disorders. Low levels may indicate starvation or malnutrition

<p>ALT (alanine transaminae) (C)</p> Signup and view all the answers

High levels may indicate a bile duct obstruction, Cushing's dz, liver dz, certain cancers and may be due to certain drugs such as steroids or phenobarbital. Low levels may indicate starvation or malnutrition

<p>ALKP (alkaline phosphatase) (D)</p> Signup and view all the answers

This animal has high levels of UREA, CREA, ALT and ALKP, what does this mean?

<p>Both A and B (D)</p> Signup and view all the answers

This animal has high level of UREA, CREA and AMYL, what does this mean

<p>Animal may have kidney failure or dz or pancreatic inflammation or cancer (C)</p> Signup and view all the answers

Leukogram patterns

<p>Neutrophilia, no left shift, lymphopenia, monocytosis (especially in dogs), no toxic change, +/- evidence of inflammation = Stress Neutrophilia, no left shift, lymphocytosis (especially in cats and young horses), no change in monocytes, no toxic change, not usually any evidence of inflammation = Physiologic Neutrophilia, +/- left shift, no change or lymphopenia, monocytosis (especially if chronic), no toxic change, hopefully evidence of inflammation = Mild/chronic inflammation Neutrophilia, left shift, lymphopenia, no change or monocytosis, usually toxic change, evidence of inflammation = Acute inflammation</p> Signup and view all the answers

Match

<p>Neutropenia, left shift, lymphopenia, no change in monocytosis, toxic change, evidence of inflammation = Overwhelming inflammation Neutrophilia, +/- left shift, no change or lymphopenia, no change or monocytosis, +/- toxic change, may be difficult to find evidence of inflammation = Sequestered inflammation</p> <ul> <li>= - 1 = 1</li> </ul> Signup and view all the answers

Which panel includes the following values: Amylase, Lipase, Glucose, C PLI, F PLI, Fructosamine, A1C

<p>Pancreas (A)</p> Signup and view all the answers

Which panel includes the following values: ALT, ALKP, ALP, GGT

<p>Liver (C)</p> Signup and view all the answers

Which panel includes the following values: BUN, CREAT, PHOS

<p>Renal (D)</p> Signup and view all the answers

Which panel includes the following values: Na, Cl, K

<p>Electrolytes (B)</p> Signup and view all the answers

Which panel includes the following values: T3, T4, Free T4

<p>Thyroid (A)</p> Signup and view all the answers

Which panel includes the following values: ACTH, Dex low, Dex high

<p>Adrenal (C)</p> Signup and view all the answers

Advantages of various tests used in the diagnosis of acute and chronic feline and canine pancreatitis

<p>Widely available on in-house analyzers, steroids do not elevate it so it can help diagnose pancreatitis in dogs with adrenocorticism = Amylase Widely available on practice analyzers, more sensitive than amylase; degree of elevation may have prognostic significance = Lipase Elevations high specificity for pancreatitis = Canine TLI Early indications most sensitive and specific test for canine pancreatitis; organ specific, so no interference from extrapancreatic sources = Canine PLI</p> Signup and view all the answers

Advantages of various tests used in the diagnosis of acute and chronic feline and canine pancreatitis

<p>One of only 2 assays available for cats = Feline TLI Very new test but appears most sensitive and specific test available for felines = Feline PLI Steroids do not elevate it so can help diagnose pancreatitis in dogs with adrenocorticism = Amylase More sensitive, degree of elevation may have prognostic significance = Lipase</p> Signup and view all the answers

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Study Notes

Blood Chemistry Panels/Profiles

  • Assess the function of internal organs, identify endocrine levels, cholesterol, electrolytes, and more

Albumin Levels

  • Produced in the liver
  • Deficiency in albumin levels indicates liver problems
  • High levels indicate stress, Cushing's disease, diabetes, pancreatitis, or certain medications
  • Low levels indicate liver disease, insulin overdose, severe bacterial infection, hypothyroidism, or Addison's disease

Total Protein Levels

  • High levels may indicate kidney failure or disease, poor circulation to the kidneys, and urinary obstruction, or dehydration
  • Low levels may indicate liver disease or starvation

Globulin Levels

  • High levels indicate kidney disease, dietary imbalance, excess ingestion of Vit D, and severe tissue trauma
  • Low levels indicate dietary imbalance, certain cancers, overdose of insulin, diabetes, eclampsia, and an overactive parathyroid gland

Calcium Levels

  • High levels indicate certain forms of cancer, Addison's disease, excess intake of Vit D, and an overactive parathyroid gland
  • Low levels indicate eclampsia, severe pancreatitis, dietary imbalance, intestinal absorption disorders, low intake of Vit D, Cushing's disease, and certain toxin ingestions

Phosphorus Levels

  • High levels indicate dehydration, inflammation, chronic infection, and certain cancers
  • Low levels indicate intestinal absorption problems, liver disease, Addison's disease, severe burns, and losses through the kidneys

Urea, Creatinine, and Other Levels

  • High levels of UREA, CREA, and ALT indicate kidney and liver damage
  • High levels of UREA, CREA, and AMYL indicate pancreatitis

Leukogram Patterns and Panels

  • Different panels include various values such as:
    • Amylase, Lipase, Glucose, C PLI, F PLI, Fructosamine, A1C (Pancreatitis panel)
    • ALT, ALKP, ALP, GGT (Liver panel)
    • BUN, CREAT, PHOS (Kidney panel)
    • Na, Cl, K (Electrolyte panel)
    • T3, T4, Free T4 (Thyroid panel)
    • ACTH, Dex low, Dex high (Adrenal panel)

Advantages of Various Tests

  • Different tests have advantages in diagnosing acute and chronic feline and canine pancreatitis

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