Vecuronium Overview and Indications

Questions and Answers

What is the trade name of Vecuronium?

Pavulon

Succinylcholine

Norcuron (correct)

Anectine

What is the classification of Vecuronium?

Neuromuscular blocker, nondepolarizing

What is the mechanism of action of Vecuronium?

Antagonizes acetylcholine at the motor end plate, producing skeletal muscle paralysis

What are the indications for using Vecuronium?

To induce neuromotor blockade for the facilitation of ET intubation Signup and view all the answers

Vecuronium can cause adverse reactions such as ______.

muscle paralysis, apnea, dyspnea, respiratory depression, sinus tachycardia, urticaria Signup and view all the answers

Some side effects of Vecuronium include ______.

anaphylaxis, bronchospasm, hypertension, tachycardia, excessive salivation, rash Signup and view all the answers

What precautions should be taken when administering Vecuronium?

Does not affect mental status; give sedative beforehand; onset within 1 minute; effects can last up to 60 minutes Signup and view all the answers

What is the adult dosage for Vecuronium?

0.08-0.1 mg/kg IV or IO; Maintenance: 0.01-0.05 mg/kg/hr Signup and view all the answers

What is the pediatric dosage for Vecuronium?

Same as adult Signup and view all the answers

Study Notes

Vecuronium Overview

Trade name for vecuronium is Norcuron.
Classified as a neuromuscular blocker, specifically a nondepolarizing type.

Mechanism of Action

Works by antagonizing acetylcholine at the motor end plate.
This action leads to skeletal muscle paralysis, essential for surgical and procedural intubation.

Indications for Use

Primarily indicated for inducing neuromuscular blockade to facilitate endotracheal intubation (ET intubation).

Adverse Reactions

Potential adverse reactions include muscle paralysis, apnea, dyspnea, respiratory depression, sinus tachycardia, and urticaria.

Side Effects

Notable side effects encompass anaphylaxis, bronchospasm, hypertension, tachycardia, excessive salivation, and rash.

Precautions

Vecuronium does not impact mental status; it is crucial to administer a sedative prior to its use.
Onset of action is within 1 minute, with effects lasting up to 60 minutes.

Dosage Guidelines

Adult dosage ranges from 0.08-0.1 mg/kg via IV or IO administration.
Maintenance dosage is between 0.01-0.05 mg/kg/hour.
Pediatric dosage is the same as adults, ensuring consistent application across age groups.

Description

This quiz covers the essential aspects of vecuronium, a neuromuscular blocker. It includes information about its mechanism of action, indications for use, potential adverse reactions, side effects, and necessary precautions. Ideal for medical and healthcare professionals preparing for surgical procedures.