Vasculitis Quiz

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Questions and Answers

Which characteristic is NOT typically associated with Giant Cell Arteritis?

  • Visual disturbances due to ischemic optic neuropathy
  • Commonly affects older adults
  • Involvement of large to medium-sized vessels
  • Presence of anti-endothelial cell antibodies (correct)

What is the primary immune mechanism implicated in Takayasu Arteritis?

  • Immune complex deposition
  • Autoantibodies against endothelial cells
  • Antineutrophil cytoplasmic antibodies
  • Autoreactive T cells (correct)

What is a distinguishing feature of Kawasaki Disease in comparison to other forms of vasculitis?

  • It is frequently associated with respiratory infections
  • It often leads to coronary artery aneurysms in children (correct)
  • It primarily targets small vessels
  • It primarily affects older adults

Which diagnostic test is specifically used for detecting infectious vasculitis caused by certain fungi?

<p>Gomori Methenamine Silver stain (C)</p> Signup and view all the answers

Which type of vasculitis is primarily associated with immune complex deposition due to drug hypersensitivity?

<p>Immune Complex–Associated Vasculitis (B)</p> Signup and view all the answers

Which of the following best describes the underlying cause of microscopic polyangiitis?

<p>Antineutrophil cytoplasmic antibodies targeting neutrophils (C)</p> Signup and view all the answers

Which feature is characteristic of the inflammatory pathways in vasculitis generally?

<p>Increased production of tumor necrosis factor-alpha (B)</p> Signup and view all the answers

What is a common clinical manifestation that would NOT be expected in vasculitis conditions?

<p>Generalized muscle weakness without inflammation (D)</p> Signup and view all the answers

Which of the following statements accurately describes Kawasaki disease?

<p>Typically presents with conjunctival erythema. (D)</p> Signup and view all the answers

What is the primary cause of acute coronary arteritis in Kawasaki disease?

<p>Viral infections in genetically susceptible individuals. (D)</p> Signup and view all the answers

Which diagnostic criteria are indicative of Kawasaki disease?

<p>Cervical lymph node enlargement. (D)</p> Signup and view all the answers

Which characteristic is notable for giant cell arteritis in contrast to Kawasaki disease?

<p>Chronic, typically granulomatous inflammation is present. (C)</p> Signup and view all the answers

What best explains the term 'pauci-immune' as it relates to ANCA-associated vasculitides?

<p>They lack significant antibodies and complement components. (D)</p> Signup and view all the answers

In Kawasaki disease, what is a major risk associated with coronary arteritis?

<p>Development of coronary artery aneurysms. (C)</p> Signup and view all the answers

Which of the following is NOT a common symptom associated with Kawasaki disease?

<p>Choanal atresia. (A)</p> Signup and view all the answers

Which factor is critically involved in the inflammatory pathway of vasculitis conditions?

<p>Direct action of ANCAs on neutrophils. (A)</p> Signup and view all the answers

What is a characteristic finding in Wegener Granulomatosis?

<p>PR3-ANCAs (c-ANCA) presence (D)</p> Signup and view all the answers

Which clinical finding is associated with Churg-Strauss syndrome?

<p>Extravascular necrotizing granulomas (D)</p> Signup and view all the answers

What distinguishes thromboangiitis obliterans from other forms of vasculitis?

<p>Granulomatous inflammation in medium and small arteries (D)</p> Signup and view all the answers

What is a major cause of morbidity in patients with Churg-Strauss syndrome?

<p>Cardiac involvement (D)</p> Signup and view all the answers

Which of the following is NOT a clinical feature of Kawasaki Disease?

<p>Focal glomerulosclerosis (C)</p> Signup and view all the answers

Which diagnostic criteria are primarily used for identifying Takayasu Arteritis?

<p>Imaging evidence of large vessel inflammation (B)</p> Signup and view all the answers

Which inflammatory pathway is primarily involved in Wegener Granulomatosis?

<p>Cell-mediated immune response (A)</p> Signup and view all the answers

What renal finding is most characteristic of Wegener Granulomatosis?

<p>Crescentic glomerulonephritis (D)</p> Signup and view all the answers

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