Vasculitis Quiz

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Which characteristic is NOT typically associated with Giant Cell Arteritis?

Visual disturbances due to ischemic optic neuropathy

Commonly affects older adults

Involvement of large to medium-sized vessels

Presence of anti-endothelial cell antibodies (correct)

What is the primary immune mechanism implicated in Takayasu Arteritis?

Immune complex deposition

Autoantibodies against endothelial cells

Antineutrophil cytoplasmic antibodies

Autoreactive T cells (correct)

What is a distinguishing feature of Kawasaki Disease in comparison to other forms of vasculitis?

It is frequently associated with respiratory infections

It often leads to coronary artery aneurysms in children (correct)

It primarily targets small vessels

It primarily affects older adults

Which diagnostic test is specifically used for detecting infectious vasculitis caused by certain fungi?

Gomori Methenamine Silver stain Signup and view all the answers

Which type of vasculitis is primarily associated with immune complex deposition due to drug hypersensitivity?

Immune Complex–Associated Vasculitis Signup and view all the answers

Which of the following best describes the underlying cause of microscopic polyangiitis?

Antineutrophil cytoplasmic antibodies targeting neutrophils Signup and view all the answers

Which feature is characteristic of the inflammatory pathways in vasculitis generally?

Increased production of tumor necrosis factor-alpha Signup and view all the answers

What is a common clinical manifestation that would NOT be expected in vasculitis conditions?

Generalized muscle weakness without inflammation Signup and view all the answers

Which of the following statements accurately describes Kawasaki disease?

Typically presents with conjunctival erythema. Signup and view all the answers

What is the primary cause of acute coronary arteritis in Kawasaki disease?

Viral infections in genetically susceptible individuals. Signup and view all the answers

Which diagnostic criteria are indicative of Kawasaki disease?

Cervical lymph node enlargement. Signup and view all the answers

Which characteristic is notable for giant cell arteritis in contrast to Kawasaki disease?

Chronic, typically granulomatous inflammation is present. Signup and view all the answers

What best explains the term 'pauci-immune' as it relates to ANCA-associated vasculitides?

They lack significant antibodies and complement components. Signup and view all the answers

In Kawasaki disease, what is a major risk associated with coronary arteritis?

Development of coronary artery aneurysms. Signup and view all the answers

Which of the following is NOT a common symptom associated with Kawasaki disease?

Choanal atresia. Signup and view all the answers

Which factor is critically involved in the inflammatory pathway of vasculitis conditions?

Direct action of ANCAs on neutrophils. Signup and view all the answers

What is a characteristic finding in Wegener Granulomatosis?

PR3-ANCAs (c-ANCA) presence Signup and view all the answers

Which clinical finding is associated with Churg-Strauss syndrome?

Extravascular necrotizing granulomas Signup and view all the answers

What distinguishes thromboangiitis obliterans from other forms of vasculitis?

Granulomatous inflammation in medium and small arteries Signup and view all the answers

What is a major cause of morbidity in patients with Churg-Strauss syndrome?

Cardiac involvement Signup and view all the answers

Which of the following is NOT a clinical feature of Kawasaki Disease?

Focal glomerulosclerosis Signup and view all the answers

Which diagnostic criteria are primarily used for identifying Takayasu Arteritis?

Imaging evidence of large vessel inflammation Signup and view all the answers

Which inflammatory pathway is primarily involved in Wegener Granulomatosis?

Cell-mediated immune response Signup and view all the answers

What renal finding is most characteristic of Wegener Granulomatosis?

Crescentic glomerulonephritis Signup and view all the answers