Vascular Dementia Quiz
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Questions and Answers

Which of the following symptoms are common in Stage 7 of dementia?

  • Increased independence in daily tasks
  • Loss of bladder/bowel control (correct)
  • Improved speech capacity
  • Inability to recognize faces
  • What is a characteristic clinical presentation of vascular dementia?

  • Persistent improvement in memory
  • Constant disorientation
  • Gradual cognitive decline
  • Step-wise deterioration (correct)
  • What is one key feature of vascular dementia that differentiates it from other types of dementia?

  • Focal neurological symptoms (correct)
  • A gradual increase in memory capacity
  • Permanent memory retention
  • Complete lack of neurological symptoms
  • Which of the following is NOT a typical management strategy for vascular dementia?

    <p>Cognitive enhancement through stimulants</p> Signup and view all the answers

    What cognitive deficits are typically seen in vascular dementia?

    <p>Aphasia, apraxia, and agnosia</p> Signup and view all the answers

    What characterizes dementia as a clinical condition?

    <p>An acquired syndrome with progressive cognitive deterioration</p> Signup and view all the answers

    Which of the following is NOT a risk factor for dementia?

    <p>High education level</p> Signup and view all the answers

    What is the estimated number of elderly individuals (60 years and older) in the Philippines by 2040?

    <p>19.7 million</p> Signup and view all the answers

    Which of the following best differentiates delirium from dementia?

    <p>Delirium is reversible while dementia is progressive</p> Signup and view all the answers

    What was the percentage of total deaths attributed to Alzheimer's and dementia in the Philippines according to WHO data published in 2020?

    <p>0.30%</p> Signup and view all the answers

    Which of the following are common signs of dementia?

    <p>Impairment of memory and behavioral changes</p> Signup and view all the answers

    What impact does dementia have on daily life?

    <p>Interferes with normal activities</p> Signup and view all the answers

    What is a key emotional aspect associated with coping with dementia?

    <p>Intense isolation and loneliness</p> Signup and view all the answers

    What role do laboratory studies play in cognitive assessments?

    <p>They can help rule out other diseases and deficiencies.</p> Signup and view all the answers

    What imaging techniques are mentioned as useful in detecting brain changes?

    <p>Computed tomography and magnetic resonance imaging.</p> Signup and view all the answers

    Which of the following symptoms is NOT associated with the early stages of Alzheimer’s?

    <p>Severe memory loss.</p> Signup and view all the answers

    During the preclinical stage of Alzheimer's, what might imaging studies reveal?

    <p>Changes in nerve cells and amyloid-ß build-up.</p> Signup and view all the answers

    What describes the symptoms present in the mild cognitive impairment stage?

    <p>More memory problems than normal for age, but mild.</p> Signup and view all the answers

    What common behavior might occur due to memory loss in Alzheimer’s patients?

    <p>Constantly misplacing items.</p> Signup and view all the answers

    At what stage of Alzheimer’s do activities of daily living (ADLs) remain unimpaired?

    <p>Preclinical stage.</p> Signup and view all the answers

    What might characterize the early symptoms of Alzheimer's?

    <p>Subtle memory loss and problems recalling familiar words.</p> Signup and view all the answers

    Which symptom is associated with the mild stage of Alzheimer’s Disease?

    <p>Memory loss</p> Signup and view all the answers

    What are the four A's of Alzheimer's disease?

    <p>Amnesia, aphasia, apraxia, agnosia</p> Signup and view all the answers

    Which hallmark is NOT consistent with the neuropathology of Alzheimer’s Disease?

    <p>Vascular occlusion</p> Signup and view all the answers

    What might a severe stage Alzheimer's patient demonstrate?

    <p>Incontinence and bedridden state</p> Signup and view all the answers

    Which of the following is a common normal lapse that differs from dementia?

    <p>Forgetting a name</p> Signup and view all the answers

    What is one method used in the diagnosis of Alzheimer's Disease?

    <p>Review of medications and current symptoms</p> Signup and view all the answers

    Which of the following is an example of apraxia associated with Alzheimer's Disease?

    <p>Putting an iron in the freezer</p> Signup and view all the answers

    What type of behavioral change might occur in the moderate stage of Alzheimer’s Disease?

    <p>Wandering and agitation</p> Signup and view all the answers

    What is an important focus for therapy in the later stages of Parkinson's?

    <p>Optimizing symptom control</p> Signup and view all the answers

    Which of the following is considered a non-motor symptom of Parkinson's?

    <p>Facial expression changes</p> Signup and view all the answers

    What should be assessed regularly for individuals with Parkinson's?

    <p>Carer support needs</p> Signup and view all the answers

    Which treatment approach can help manage freezing episodes in Parkinson's patients?

    <p>Queuing techniques</p> Signup and view all the answers

    What is a common complication that should be checked for in those with Parkinson's?

    <p>Urinary tract infection (UTI)</p> Signup and view all the answers

    What symptom may limit a Parkinson's patient's ability to communicate effectively in a group setting?

    <p>Slurred speech</p> Signup and view all the answers

    Which of the following is crucial for maintaining dignity in advanced Parkinson's care?

    <p>Palliative care approaches</p> Signup and view all the answers

    What is a key aspect of supporting carers of individuals with Parkinson's?

    <p>Providing them with educational resources</p> Signup and view all the answers

    What is the primary purpose of melatonin during night time care?

    <p>Promote the sleep process</p> Signup and view all the answers

    Which factor is NOT mentioned as a consideration for night time care?

    <p>Increased physical activity</p> Signup and view all the answers

    What should caregivers do to help manage chronic pain in individuals with dementia?

    <p>Assess and address pain adequately</p> Signup and view all the answers

    Which of the following is a nonpharmacologic approach to treating psychosis in dementia?

    <p>Cognitive enhancement</p> Signup and view all the answers

    What is a recommended strategy for minimizing noise during night time care?

    <p>Eliminate unnecessary sounds</p> Signup and view all the answers

    Which of the following medications is considered an atypical antipsychotic?

    <p>Risperidone</p> Signup and view all the answers

    What is a common symptom that may accompany disorientation in individuals with dementia at night?

    <p>Sleep disturbances</p> Signup and view all the answers

    Why should caregivers avoid arguing with individuals with dementia?

    <p>It can create confusion</p> Signup and view all the answers

    Study Notes

    Virtual Classroom Information

    • Dr. J.S. Espiritu is an Associate Professor
    • The virtual classroom is for Gerontology, Older Adults, Geriatric NSG, and Advocates.
    • Virtual meeting tools include Meet, FlipGrid, and a video-conferencing platform.

    Prayer

    • The prayer thanks Heavenly Father for the gift of education, and hopes students will be confident, guided by grace, and have hope for their future.
    • The prayer expresses a desire for students to see needs of others, love well, and face each day with positivity.

    NCM 114 Care of the Older Adult

    • This is a course topic
    • The course focuses on care for the elderly.

    Learning Outcomes: Care of Older Adults with Dementia

    • Define dementia
    • Differentiate delirium and dementia
    • Differentiate depression and dementia
    • Causes of dementia
    • Management of dementia

    Couch Potato

    • An image of a potato in a chair with chips
    • The image is meant as a commentary on the lifestyles of some elderly people.
    • Getting old is associated with a lack of purposeful activities.

    Dementia: Symptoms, Cause, and Treatment

    • Pictures of the brain and different brain areas are shown.
    • The presentation covers symptoms, causes, and treatments.

    Dementia as a Syndrome

    • Dementia is an acquired syndrome of progressive cognitive decline.
    • Memory, thinking, behavior, and daily activities are affected.
    • Cognitive decline impacts daily life.

    Types of Dementia

    • Alzheimer's (50%-75%)
    • Vascular (20%-30%)
    • Lewy Body (10%-25%)
    • Frontotemporal (10%-15%)
    • Mixed dementia comes from more than one cause.

    Dementia as a Complex Syndrome

    • Dementia is characterized by cognitive, behavioral, and functional impairments.
    • Cognitive impairments include amnesia, aphasia, agnosia, and apraxia.
    • Behavioral impairments include behavioral disturbances and psychological/psychiatric symptoms.
    • Functional impairments include instrumental ADLs and personal ADLs.

    Risk Factors for Dementia

    • Age
    • Family history
    • Head injury
    • Fewer years of education are risk factors.

    Philippines Dementia Prevalence and Statistics

    • The estimated number of older adults in the Philippines (60 years or older) will double from 9.5 million in 2020 to 19.7 million in 2040.
    • In 2020, Alzheimer's & Dementia deaths reached 2,010 (0.30% of total deaths) in the Philippines.
    • The age-adjusted death rate is 3.10 per 100,000, and ranks Philippines #172 in the world.
    • Globally, over 60% of dementia cases reside in low/middle income countries.

    Healthy and Pathological Aging

    • Various risk factors across the lifespan are associated with abnormal aging.
    • Exposure to factors such as unhealthy diet, smoking, alcohol misuse, depression and diabetes are risk factors.
    • These can contribute to neuronal damage, vascular insults, and dementia risk.
    • AD risk impacts neuron viability, inflammation, oxidative stress, glucose metabolism, and tau and amyloid removal.

    Impact of COVID-19 in People with Dementia

    • People with dementia (65+) are at higher risk of COVID-19.
    • 2020 witnessed a 16% increase in dementia-related deaths.
    • Underlying health problems exacerbate COVID-19 complications in people with dementia,

    COVID-19 and the Brain

    • Studies suggest COVID-19 can enter the brain.
    • Mechanisms of impact can be direct or indirect, relating to: blood-brain barrier, inflammation/immune response, or vascular connections.

    Cognitive Disorders: Dementia

    • Dementia is a clinical condition / syndrome involving a loss of cognitive function.
    • Cognitive loss affects normal activities and social relationships.
    • Common signs include memory impairment, cognitive disturbances and executive functioning.

    Dementia: General Details

    • Progressive and disabling
    • Not an inherent aspect of aging
    • Different from normal cognitive lapses

    Types of Dementia

    • Vascular dementia
    • Alzheimer's disease
    • Dementia with Lewy bodies
    • Frontotemporal dementia (Pick's disease)
    • Dementia from Parkinson's disease
    • Creutzfeldt-Jakob disease

    The Big Four Types of Dementia

    • Lewy Body Dementia effects entire brain, widely diverse in symptoms.
    • Alzheimer's Disease affects hippocampus at cortex base.
    • Vascular Dementia affects entirety of brain, symptoms widely diverse.
    • Frontotemporal Dementia affects frontal and temporal lobes.

    Signs and Symptoms of Dementia: Recognizing Warning Signs

    • Memory loss is a common early symptom of dementia.
    • Difficulty with everyday activities (e.g., cooking, dressing, personal hygiene) is a sign.
    • Language problems and communication difficulties
    • Changes in mood and behavior

    Stages of Dementia

    • Stage 1 involves a lack of noticeable cognitive changes.
    • Stage 2: mild cognitive changes
    • Stage 3: mild but noticeable cognitive changes
    • Stage 4: mild dementia
    • Stage 5: moderate to severe dementia
    • Stage 6: severe dementia
    • Stage 7: very severe dementia.

    Dementia: Symptoms (Stage 4)

    • Choking, difficult swallowing, aspiration, excessive drooling
    • Life-disrupting forgetfulness
    • Difficulty performing daily activities
    • High risk of falls
    • Tremors
    • Increased daytime sleep but few hallucinations
    • High risk of potential health problems
    • Increased need for supervision

    Stage-Specific Symptoms of Dementia

    • Stage 5: moderate to severe dementia, ability to recognize family and friends but recalling past events challenging. Requires assistance in daily tasks.
    • Stage 6: severe dementia; major memory loss, incontinence is common. Difficulty recognizing family, communication problems, personality/mood changes and wandering are typical.
    • Stage 7: the final stage of dementia, lasting approximately 1.5-2.5 years. Complete dependence on care, inability to speak, eat, or swallow, incontinence, lack of muscle control, constant disorientation.

    Stage 7 Symptoms

    • Inability to speak, eat, or swallow
    • Loss of bladder/bowel control
    • Assistance needed for every task
    • No muscle control
    • Constant disorientation
    • Patient is bedridden

    Vascular Dementia

    • Development of cognitive deficits from both impaired memory, aphasia, apraxia, agnosia to disturbed abilities.
    • Significant impairment in social and occupational functioning.
    • Focal neurological symptoms and signs or evidence of cerebrovascular disease. Deficits occur in absence of delirium.

    Vascular Dementia: Clinical Presentation

    • Abrupt onset, step-wise deterioration
    • Somatic complaints and emotional incontinence
    • Hypertension and cerebrovascular history of disease/stroke are present
    • Focal neurological symptoms/signs are found

    Management of Vascular Dementia

    • Risk assessment: age, hypertension, smoking, diabetes and history of stroke.
    • Risk of further damage is reduced through management of stroke and risk factors.
    • Secondary conditions (e.g., depression, anxiety, agitation) are treated.
    • Dementia symptoms (cognition, global function, daily activities), are addressed in treatment.

    Alzheimer's Disease

    • A brain condition causing a progressive decline in memory, thinking, learning, and organizing skills.
    • Eventually affects ability to carry out basic daily activities.
    • Most common cause of dementia.

    Alzheimer's Disease and Stages

    • Signs vary in severity from Mild to Severe
    • Symptoms include: Memory loss, Language problems, Mood swings, Personality changes, and Judgement
    • Progression is categorized as Mild, Moderate, and Severe Stages

    Normal Lapses vs. Dementia

    • Normal Lapses: forgetting a name, leaving a kettle on, struggling for a word, or forgetting a date.

    Normal Lapses Vs Dementia

    • Dementia signs include problems remembering numbers, putting iron in the freezer, rapid mood swings for no reason and sudden changes in personality.

    Four A's of Alzheimer's Disease

    • Amnesia: loss of memory, the most common symptom of Alzheimer's disease.
    • Aphasia: difficulty with language.
    • Apraxia: difficulty with movement
    • Agnosia: difficulty recognizing objects or people.

    Pathology of Alzheimer's Disease (AD)

    • Three key pathological hallmarks are present: Amyloid-rich senile plaques, Neurofibrillary tangles, Neuronal degeneration.
    • Changes begin before symptoms emerge.

    Alzheimer's Dementia: Brain Changes

    • Healthy brain size and a shrunken brain due to Alzheimer's disease.
    • Dying neurons showing tangles

    Alzheimer's Disease - Symptoms

    • Memory problems
    • Trouble with decision making
    • Sleep difficulties
    • Inability to recognize people or things
    • Communication difficulties
    • Difficulty completing tasks
    • Behavior changes
    • Social withdrawal
    • Forgetfulness
    • Agressiveness.

    Diagnosis and Management of Alzheimer's Disease

    • Medical history & physical examination
    • Review of current and past illnesses, medications and symptoms helps.
    • Medical tests (laboratory studies & hormonal/vitamin deficiencies) help rule out other conditions.
    • Brain imaging (e.g., CT, MRI) detects brain shrinkage, structural abnormalities.
    • Neuropsychological tests assess memory and cognitive abilities to identify affected brain regions.

    Cognitive, Psychiatric / Behavioral, and Physical Aspects of Dementia

    • Cognitive impairments (non-amnestic, fluctuations)
    • Psychiatric/behavioral symptoms (REM sleep behavior disorder, hallucinations, depression, delirium)
    • Physical symptoms (Parkinsonism, hyposmia, constipation, orthostatic hypotension)

    Stages of Alzheimer's Disease

    • Stage 1: Preclinical Alzheimer's (no symptoms, brain changes)
    • Stage 2: Mild Cognitive Impairment (more memory problems, daily function still maintained.)
    • Stage 3: Mild Dementia (symptoms interfere with daily activities, noticeable cognitive decline).
    • Middle Stage has noticeable cognitive changes
    • Late Stage has worsening visual or spatial problems plus mental & behavioral problems.

    Alzheimer's Treatment

    • No cure, but treating aspects of disease

    Sundowning

    • Increased confusion, anxiety/agitation, sleep difficulties, pacing/wandering, disorientation are common issues for Alzheimer's/dementia patients that occur during evening hours.

    Lewy Body Dementia (LBD)

    • A brain disease with abnormal protein deposits (alpha-synuclein).
    • Affects chemicals leading to problems with thinking, movement, behavior, and mood.
    • Caused by abnormal protein deposits disrupting brain function and dopamine levels.

    Dementia 7 Stages: Lewy Bodies

    • Stage 1 - no noticeable cognitive changes are found
    • Stage 2 - mild cognitive changes
    • Stage 3 - noticeable cognitive changes
    • Stage 4 - early signs of dementia
    • Stage 5 - moderate to severe dementia
    • Stage 6 - severe dementia
    • Stage 7 - late or final stage dementia

    frontotemporal dementia (FTD)

    • Degeneration of frontal and temporal lobes
    • Associated with Pick's bodies (tau protein) and Chr17 abnormality.
    • Common Symptoms include: behavioral changes:
    • (loss of job, compulsive, impulsive, difficulties interacting, hygiene, repetitive behaviors, withdrawal)
    • Initial neurological symptoms (problems walking, slurred speech, numbness, dizziness, vision probs, hallucinations)).

    Creutzfeldt-Jakob Disease (CJD)

    • A rare brain disease affecting people (typically >60 years of age)
    • Rapid progression, can cause dementia.
    • Three types: sporadic, hereditary, acquired.
    • Symptoms involve behavioral changes, memory issues, personality changes, vision problems, and muscle coordination problems.

    Parkinson's Disease

    • A neurological syndrome caused by low dopamine levels in the brain.
    • Incurable, degenerative disease that affects movement and other areas of daily life.
    • Symptoms include bradykinesia (slowness), rigidity (stiffness) tremor (shaking) and postural instability.
    • A lack of dopamine leads to problems with movement and related tasks like walking and speech, among others.

    Parkinson's Disease: Diagnosis & Treatment Stages Early/Maintenance

    • Early diagnosis and management.
    • Educate the person and caregivers.
    • Reducing symptoms and distress
    • Maintaining normal activities, function, & self-care. Assess carer needs for symptom reduction and treatment compliance.

    Parkinson's Disease: Later Stages-Management

    • Adaptations to promote self-care, optimize symptom control.
    • Assess for complications and treatment fluctuations.
    • Minimise disability through MDT input, carer support, and annual reviews.
    • Palliative care with symptom relief, distress reduction and dignity.

    Effects of Parkinson's Disease

    • Motor symptoms affecting physical capability
    • Nonmotor symptoms affect everything governed by muscles and fluctuate throughout the day.

    Supporting Parkinson's People & Caregivers

    • Support people with Parkinson's and their close contacts.
    • Educate home care workers
    • Refer to specialists for issues such as speech, swallowing, dietary intake, and physiotherapy
    • Use specific techniques like queuinging or marching during freezing periods to create rhythm.

    Types of Troubleshooting for Parkinson's

    • UTI, constipation, medication changes (doses, timing, etc.)
    • These may contribute to functional impairment.

    Dementia Care

    • Responding with a calm & positive manner.
    • Reassure the patient and validate their emotions
    • Removing yourself temporarily is useful if needed and to regroup.
    • Returning to assist when the situation has calmed.

    Night-time care

    • Night-time care may need to accommodate different cultures and experiences.
    • Important to understand cues and address concerns.
    • Provide a safe and comfortable sleep environment (minimise noise and light, establish routine, provide night-light if needed).

    Night-time Experiences

    • Experiences like fears, worries, misunderstood cues & disorientation.

    Noise

    • Quiet is important for good sleep, may cause disorientation/confusion/fear.
    • Try reducing noise to minimise issues.

    Light

    • Darkness at night & bright light during the day helps regulate sleep-wake cycles.
    • Melatonin secretion is influenced by light.

    Night-Time Lighting Strategies

    • Utilize light-blocking curtains, minimise light under doors, use night lights appropriately, minimise electronics, use automatic light activation, use dimmer switches, use torches carefully.

    Nutrition

    • Hunger & hydration are important considerations, especially if dinner to breakfast is over 12 hours.

    Activities

    • Engagement in activities can be beneficial but individuals may need assistance in initiating activities.
    • Reviewing life stories can be significant.

    Pain

    • Increases with age, expressed differently in those with dementia and other complications and affects quality of life.

    Sensory Experience

    • Important to note sensory input.

    symptom management

    • Treat Psychoses (delusions & hallucinations)
    • Manage sleep disturbances
    • Address Aggression & Agitation

    Non-Pharmacological Treatments for Dementia

    • Cognitive enhancement, individual/group therapy, regular appointments, communication with family/caregivers, environmental modification, and attention to safety are important.

    Pharmacological Treatments for Dementia

    • Cholinesterase inhibitors (offer some improvement in cognition and activities of daily living) Example: donepezil, rivastigmine, galantamine
    • Memantine (NMDA Antagonist).

    Treatment: Alzheimer's Disease: Specific Drugs

    • Tacrine
    • Memantine/namenda
    • Seligiline

    Treating Psychoses with Dementia

    • Higher potency antipsychotics (e.g., haloperidol) but can have side effects (extrapyramidal symptoms).
    • Lower potency antipsychotics (e.g., thioridazine) but can have side effects (anticholinergic effects, sedation, hypotension, constipation, urinary retention).
    • Atypical antipsychotics (e.g. clozapine, risperidone, olanzapine) are also used with caution due to new prescribing information.

    Managing Sleep Disturbances with Dementia

    • Consistent bedtime and comfortable setting.
    • Providing daytime activities & avoidance of daytime sleeping.
    • Bright light therapy.
    • Treating associated conditions like depression and delusions
    • Consider trazodone, nefazodone, or zolpidem (if above methods fail), but avoid benzodiazepines or antihistamines.

    Managing Agitation with Dementia

    • Behavioral interventions like distraction, supervision, routines and structure.
    • Rewards programs can modify behaviors.
    • Pharmacological methods such as antipsychotics, antidepressants, mood stabilizers and beta-blockers.

    Five Rs of Dementia Care

    • Remain calm.
    • Respond to feelings.
    • Reassure your loved one.
    • Remove yourself (physically or psychologically) to regain composure.
    • Return after calming down.

    General Dementia Care Considerations

    • Remember, you cannot separate the emotional connection from irrational behaviors but maintain best response manners.

    AIDS & Dementia

    • Approximately two-thirds of people with AIDS develop dementia (AIDS dementia complex).
    • In some cases, HIV is found in CNS postmortem; others point to an unidentified pathogen or immune mechanism.
    • Dementia is often subcortical.
    • Treatment with AZT halts and reverses some neuropsychological deficits.

    References

    • Brunner & Suddarth Textbook of Medical-Surgical Nursing (Chapter 17).
    • www.sharecare.com
    • [URL for urinary incontinence] (Note: URL removed since it's not possible to verify this specific URL)

    Quote

    • Age wrinkles the body; quitting wrinkles the soul. - Douglas MacArthur

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