Valerian Rhizome Composition

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Questions and Answers

What is the minimum percentage of extractable matters in Valeriana?

  • 20%
  • 15% (correct)
  • 10%
  • 5%

Which of the following is NOT an active constituent of Valeriana?

  • Flavonoids (correct)
  • Alkaloids
  • Valepotriates
  • Volatile oil

What are valepotriates in Valeriana primarily composed of?

  • Sesquiterpenes and flavonoids
  • Phenols and terpenes
  • Esters and alcohols
  • Acevaltrate, didrovaltrate, and valtrate (correct)

Which property is associated with Valeriana due to the presence of valepotriates?

<p>Cytotoxic (B)</p> Signup and view all the answers

For what therapeutic use is Valeriana NOT generally used?

<p>To treat inflammation (A)</p> Signup and view all the answers

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Study Notes

Valerian Rhizome

  • Originates from the rhizome, stolons, and roots of Valeriana officinalis, a plant belonging to the Valerianaceae family.
  • Collected in the autumn and dried at a temperature below 40°C to preserve its properties.

Composition

  • Consists of at least 15% extractable matters.
  • Contains volatile oil (0.5-1%) comprising esters, alcohols, terpenes, and sesquiterpenes.
  • Rich in valepotriates (epoxy-iridoids esters), a mixture of acevaltrate, didrovaltrate, and valtrate.
  • Alkaloids (0.05-1%) are also present, including valerine.

Therapeutic Uses

  • Used as a sedative to treat hysteria, nervous disorders, and insomnia to induce sleep.
  • Can be used alone or in combination with other sedatives, such as bromides.
  • Exhibits cytotoxic properties in vitro due to the presence of valepotriates.
  • Possesses carminative properties.

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