term 2- lec 5

E-cadherin

Contain a group of proteins named connexins b. Gap-junctions allow the passage of ions to travel between cells synchronising the contractions of the heart c. Gap-junctions are a type of cell-cell junctions Gap-junctions are important components of the electrical synapse

FAK can integrate signals from integrins and RTKs and are overexpressed in cancer

Barrier function and selective function

Innate immunity protects against infections and provides the early line of response against pathogens, it involves macrophages, neutrophils, eosinophils, basophils, mast cells, and dendritic cells. b. Natural barriers such as skin are also part of the innate immunity c. The innate immune system uses a diversity of cellular receptors to recognise and respond to pathogens. d. Innate immunity receptors bind pathogen surfaces directly and often bind to repeating patterns, for example, of carbohydrate or lipid moieties, that are characteristic of microbial surfaces but are not found on host cells

Natural barriers such as skin are also part of the innate immunity

Occurs after exposure to an antigen either from a pathogen or a vaccination.