term 2- lec 5
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Questions and Answers

What is a critical component of adherens junctions

  • E-cadherin (correct)
  • Fibronectin
  • Focal adhesion kinase
  • Protein A
  • GAP-junctions:

  • Contain a group of proteins named connexins b. Gap-junctions allow the passage of ions to travel between cells synchronising the contractions of the heart c. Gap-junctions are a type of cell-cell junctions Gap-junctions are important components of the electrical synapse (correct)
  • Gap-junctions are important components of the electrical synapse
  • Gap-junctions are a type of cell-cell junctions
  • Gap-junctions allow the passage of ions to travel between cells synchronising the contractions of the hea
  • Which statement is true about FAK?

  • FAK does not phosphorylate intracellular substrates
  • FAK can integrate signals from integrins and RTKs and are overexpressed in cancer (correct)
  • Is constitutively active in children above 10
  • Is lost during ageing
  • What are two functions of tight junctions?

    <p>Barrier function and selective function</p> Signup and view all the answers

    What is true about innate immunity?

    <p>Innate immunity protects against infections and provides the early line of response against pathogens, it involves macrophages, neutrophils, eosinophils, basophils, mast cells, and dendritic cells. b. Natural barriers such as skin are also part of the innate immunity c. The innate immune system uses a diversity of cellular receptors to recognise and respond to pathogens. d. Innate immunity receptors bind pathogen surfaces directly and often bind to repeating patterns, for example, of carbohydrate or lipid moieties, that are characteristic of microbial surfaces but are not found on host cells</p> <p>Natural barriers such as skin are also part of the innate immunity</p> Signup and view all the answers

    What is true about adaptive immunity?

    <p>Occurs after exposure to an antigen either from a pathogen or a vaccination.</p> Signup and view all the answers

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