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UST-FOP 2024 Calcium Channel Blockers Clinical Uses Quiz

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17 Questions

Which condition is NOT listed as a clinical use of Calcium Channel Blockers?

Atherosclerotic angina attacks

Which adverse effect is specifically associated with Verapamil among the Calcium Channel Blockers?

Constipation

What is the primary mechanism of action of Beta-Blockers in reducing O2 demand of the myocardium?

Reducing inotropy and chronotropy

Which condition is NOT a clinical use of Beta-Blockers?

Treatment of hypertrophic cardiomyopathy

Which side effect is commonly associated with Beta-Blockers according to the text?

Bradycardia

Which of the following is a contraindication for the use of beta-blockers?

Asthma

Which of the following adverse effects is NOT commonly associated with the use of beta-blockers?

Increased appetite

What is the primary mechanism of action of ranolazine in the treatment of angina?

Inhibition of the late sodium current (INa)

What is the primary mechanism of action of trimetazidine in the treatment of angina?

Inhibition of fatty acid oxidation

What is the primary mechanism of action of ivabradine in the treatment of angina?

Inhibition of the If current in the sinoatrial node

Which of the following is a mechanism of action of nicorandil in the treatment of angina?

Activation of the sodium-calcium exchanger

Which adverse effect is associated with Calcium Channel Blockers according to the provided text?

Throbbing headache

What is the main mechanism of action of Calcium Channel Blockers on blood vessels?

Relaxation of arterioles

Which condition shows a more significant reduction in blood pressure with Diltiazem, according to the text?

Women

What is the term used to describe the alternating tolerance and loss of tolerance for the vasodilating action of nitrates?

Monday disease

In which condition can calcium channel blockers potentially lead to fluid retention?

Congestive heart failure

What type of Ca-channel do Calcium Channel Blockers predominantly block in cardiac and smooth muscle?

$\alpha1$-subunit Ca-channel (DHP)

Test your knowledge on the clinical uses of calcium channel blockers (CCBs) including hypertension, arrhythmia, hypertrophic cardiomyopathy, migraine, and Raynaud's phenomenon. Learn about specific CCBs for conditions like hypotension, preterm labor, AV conduction abnormalities, heart failure, and atrial flutter/fibrillation. Prepared by Asst. Prof. Charliemaign Stanley S. Cruz, RPh, MSc.

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