17 Questions
Which condition is NOT listed as a clinical use of Calcium Channel Blockers?
Atherosclerotic angina attacks
Which adverse effect is specifically associated with Verapamil among the Calcium Channel Blockers?
Constipation
What is the primary mechanism of action of Beta-Blockers in reducing O2 demand of the myocardium?
Reducing inotropy and chronotropy
Which condition is NOT a clinical use of Beta-Blockers?
Treatment of hypertrophic cardiomyopathy
Which side effect is commonly associated with Beta-Blockers according to the text?
Bradycardia
Which of the following is a contraindication for the use of beta-blockers?
Asthma
Which of the following adverse effects is NOT commonly associated with the use of beta-blockers?
Increased appetite
What is the primary mechanism of action of ranolazine in the treatment of angina?
Inhibition of the late sodium current (INa)
What is the primary mechanism of action of trimetazidine in the treatment of angina?
Inhibition of fatty acid oxidation
What is the primary mechanism of action of ivabradine in the treatment of angina?
Inhibition of the If current in the sinoatrial node
Which of the following is a mechanism of action of nicorandil in the treatment of angina?
Activation of the sodium-calcium exchanger
Which adverse effect is associated with Calcium Channel Blockers according to the provided text?
Throbbing headache
What is the main mechanism of action of Calcium Channel Blockers on blood vessels?
Relaxation of arterioles
Which condition shows a more significant reduction in blood pressure with Diltiazem, according to the text?
Women
What is the term used to describe the alternating tolerance and loss of tolerance for the vasodilating action of nitrates?
Monday disease
In which condition can calcium channel blockers potentially lead to fluid retention?
Congestive heart failure
What type of Ca-channel do Calcium Channel Blockers predominantly block in cardiac and smooth muscle?
$\alpha1$-subunit Ca-channel (DHP)
Test your knowledge on the clinical uses of calcium channel blockers (CCBs) including hypertension, arrhythmia, hypertrophic cardiomyopathy, migraine, and Raynaud's phenomenon. Learn about specific CCBs for conditions like hypotension, preterm labor, AV conduction abnormalities, heart failure, and atrial flutter/fibrillation. Prepared by Asst. Prof. Charliemaign Stanley S. Cruz, RPh, MSc.
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