Urine Analysis Review Quiz

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Questions and Answers

What effect might occur with an unpreserved urine sample?

  • Decrease in pH levels
  • Growth of yeast colonies
  • Trichomonas will increase in number (correct)
  • Decrease in specific gravity

Which of the following changes is least likely to occur in an unpreserved urine sample?

  • Increased nitrite levels
  • Stability of bacteria counts (correct)
  • Decrease in glucose concentration
  • Formation of crystals

In an unpreserved urine sample, which alteration is most probable?

  • Increase in ketones
  • Trichomonas proliferation (correct)
  • Formation of casts
  • Degradation of urobilinogen

Which statement about unpreserved urine is accurate?

<p>Microbial growth is likely (A)</p> Signup and view all the answers

What change can be expected in the composition of unpreserved urine over time?

<p>Decrease in pH due to bacterial metabolism (A)</p> Signup and view all the answers

Which structure is responsible for delivering blood away from the kidney?

<p>Renal vein (B), Efferent arteriole (C)</p> Signup and view all the answers

Which part of the nephron is primarily involved in water reabsorption?

<p>Proximal convoluted tubule (C)</p> Signup and view all the answers

What is the function of the afferent arteriole in the renal system?

<p>To supply blood to the glomerulus (D)</p> Signup and view all the answers

Which of the following structures contributes to the concentration of urine?

<p>Vasa recta (B), Nephron loop (D)</p> Signup and view all the answers

What happens to water during the process of filtration at the glomerulus?

<p>It is filtered out along with solutes into the Bowman's capsule (D)</p> Signup and view all the answers

What characteristic is true about Bence Jones protein?

<p>It dissolves at 100°C and coagulates at 40-60°C. (C)</p> Signup and view all the answers

At what temperature range does Bence Jones protein coagulate?

<p>40-60°C (C)</p> Signup and view all the answers

Which of the following statements is incorrect regarding Bence Jones protein?

<p>It dissolves at 50°C. (B)</p> Signup and view all the answers

What can be inferred about the behavior of Bence Jones protein under heat?

<p>It undergoes phase changes with specific temperature changes. (A)</p> Signup and view all the answers

In which condition is Bence Jones protein typically observed?

<p>Multiple myeloma (D)</p> Signup and view all the answers

Which of the following organisms is primarily associated with eosinophils in the immune response?

<p>Candida albicans (A)</p> Signup and view all the answers

Which cell type is responsible for phagocytosis and presents antigens to T cells?

<p>Macrophage (C)</p> Signup and view all the answers

Which of the following is a fungal organism that can cause opportunistic infections?

<p>Candida albicans (A), Cryptococcus neoformans (D)</p> Signup and view all the answers

In the context of the immune system, which of these options is mainly responsible for allergic reactions?

<p>Eosinophils (D)</p> Signup and view all the answers

Which of the following cells is primarily a phagocyte and not involved in the allergic response?

<p>Macrophage (D)</p> Signup and view all the answers

What indicates widening of renal tubules?

<p>Increased presence of crystals (B)</p> Signup and view all the answers

What is true about casts in urine analysis?

<p>Casts can be of any type (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of crystals in urine?

<p>They are always harmful (A)</p> Signup and view all the answers

What could the presence of renal tubules widening indicate?

<p>Acute tubular necrosis (A)</p> Signup and view all the answers

In the context of urine analysis, what is a cast?

<p>A solid deposit formed from crystals (D)</p> Signup and view all the answers

Which volume statement is true regarding urates being soluble in heat?

<p>15 mL (A)</p> Signup and view all the answers

What can be concluded if both statements regarding urates are correct?

<p>Heat increases the solubility of urates. (B)</p> Signup and view all the answers

If Statement 1 about urates is inaccurate, which conclusion can be drawn?

<p>Urates have varying solubility in different conditions. (D)</p> Signup and view all the answers

Which is a possible misconception about urate solubility?

<p>Urates dissolve better at lower temperatures. (A)</p> Signup and view all the answers

Based on the given statements, what would be an incorrect interpretation of their meaning?

<p>Only one of the two statements reflects the truth. (B)</p> Signup and view all the answers

Which of the following statement/s about urine is true?

<p>It is a liquid biopsy of the urinary tract. (A), It is an ultrafiltrate of plasma. (B), Its normal color ranges from straw to amber. (C)</p> Signup and view all the answers

What is the composition of urine?

<p>95% water, 5% solutes (D)</p> Signup and view all the answers

The following are the organic substances normally present in the urine;

<p>Uric acid (A), Hippuric acid (B), Creatinine (C), Urea (D)</p> Signup and view all the answers

What are the inorganic substances normally present in the urine?

<p>Chloride, Sodium, Potassium, Sulfate, Phosphate, Ammonium, Magnesium, Calcium (C)</p> Signup and view all the answers

What is the major organic component of urine?

<p>Urea (C)</p> Signup and view all the answers

What is the normal daily urine output?

<p>All of the following are within the normal range. (B)</p> Signup and view all the answers

Match the following terms with their respective definition.

<p>Polyuria = Decrease urine output Oliguria = Painful urination Anuria = Increased excretion at night Dysuria = Increased urine output Nocturia = Complete cessation of urine flow</p> Signup and view all the answers

What condition/s is/are associated with polyuria?

<p>Both a and b (A)</p> Signup and view all the answers

Obstruction of the urinary tract due to infection and presence of crystals is associated with

<p>Oliguria (A)</p> Signup and view all the answers

What is the major cause of UTI which is known to have a burning sensation?

<p>Escherichia coli (D)</p> Signup and view all the answers

Painful urination occurs due to the following, except;

<p>None of the following (A)</p> Signup and view all the answers

What is the normal day to night urine ratio?

<p>2:1-3:1 (A)</p> Signup and view all the answers

What is the major pigment present in the urine that causes its yellow color?

<p>Urochrome (A)</p> Signup and view all the answers

Which of the following conditions cause increased urochrome excretion?

<p>Fever, starvation and thyrotoxicosis (A)</p> Signup and view all the answers

Which of the following does the uroerythrin is most evident?

<p>A urine left standing at room temperature. (D)</p> Signup and view all the answers

Which is true about uroerythrin?

<p>Both A and B (C)</p> Signup and view all the answers

What is an oxidation product of the normal urinary constituent which imparts an orange-brown color to urine that is not fresh?

<p>Urobilin (C)</p> Signup and view all the answers

Which of the following statements is/are true?

<p>Bacteria cause the oxidation of urobilinogen to urobilin. (C)</p> Signup and view all the answers

What is the most common method of urine preservation?

<p>Refrigeration (D)</p> Signup and view all the answers

What characteristic of urine serves as an indicator of a person's hydration status?

<p>Color (C)</p> Signup and view all the answers

What substance causes a burgundy red or port wine urine?

<p>Porphobilinogen (C)</p> Signup and view all the answers

What substance causes smoky red-brown urine?

<p>Hemoglobinuria (C)</p> Signup and view all the answers

Which is/are true about Rifampin?

<p>It causes a red orange urine (A), Also known as Rifampicin (C), A primary drug for tuberculosis (D)</p> Signup and view all the answers

What is the color of urine in lead porphyrinuria (lead poisoning)?

<p>Red (D)</p> Signup and view all the answers

What is the color of urine in patients taking anti-malarial drug atabrine?

<p>Green (D)</p> Signup and view all the answers

Urine: well hydrated; urine: dehydrated

<p>Pale yellow, Dark yellow (D)</p> Signup and view all the answers

Diluted urine:_ specific gravity; Concentrated urine:_ specific gravity

<p>Increase, decrease (B)</p> Signup and view all the answers

Flashcards

Urine composition

Urine is primarily 95% water and 5% solutes.

Urine organic components

Urea, creatinine, uric acid, and hippuric acid are examples of organic substances often found.

Urine inorganic components

Inorganic compounds like chloride, sodium, potassium, sulfate, phosphate, ammonium, magnesium, and calcium are present in urine.

Urine's major organic component

Urea is the major organic component in urine.

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Urine's major inorganic component

Chloride, a mineral ion, often features prominently.

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Urine color

Normal urine color ranges from straw to amber.

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Liquid biopsy of urinary tract

Urine is considered a liquid biopsy because it offers information about the urinary tract.

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Urine's origin

Urine is an ultrafiltrate of blood plasma.

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Urochrome

Urochrome is a substance determining urine's color.

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Increased urochrome excretion

Fever, starvation, and thyrotoxicosis can increase urochrome excretion.

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Uroerythrin

A pink pigment, most apparent in unfresh urine, uroerythrin plays a role in urine color.

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Urobilin

Urobilin is an oxidation product of urobilinogen, imparting an orange-brown color to stale urine.

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Urobilinogen

A precursor to urobilin, urobilinogen is the initial state of the pigment.

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Urine preservation method

Refrigeration is the most common method to preserve urine samples.

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Urine characteristics

Characteristics of urine, including color and composition, provide insights into health.

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Efferent Arteriole

The efferent arteriole carries filtered blood away from the glomerulus in the kidney, delivering it to the peritubular capillaries for further processing.

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Proximal Convoluted Tubule (PCT)

The PCT is the first segment of the renal tubule where most of the water and solutes are reabsorbed back into the bloodstream from the filtrate.

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What does the efferent arteriole do?

The efferent arteriole carries filtered blood away from the glomerulus and delivers it to the peritubular capillaries.

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Where does most water reabsorption occur?

The Proximal Convoluted Tubule (PCT) is the primary site of water and solute reabsorption in the kidney.

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What is the role of the peritubular capillaries?

Peritubular capillaries surround the renal tubules, assisting in the reabsorption of water and solutes back into the bloodstream.

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Unpreserved Urine Change: Trichomonas

Trichomonas, a type of parasite, can increase in number if urine is not preserved, possibly leading to inaccurate results.

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Unpreserved Urine Change: Red Blood Cells

Red blood cells can lyse (break down) in unpreserved urine, making accurate red blood cell count and analysis difficult.

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Unpreserved Urine Change: Bacteria

Bacteria can multiply in unpreserved urine, leading to changes in the urine's composition and possibly affecting test results.

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Unpreserved Urine Change: Casts

Casts, made of protein, can break down and dissolve in unpreserved urine, making them hard to detect.

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Unpreserved Urine: What Changes?

Unpreserved urine can undergo several changes, including an increase in bacteria, lysis of red blood cells, breakdown of casts, and a rise in Trichomonas.

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Eosinophil

A type of white blood cell (WBC) that is involved in allergic reactions and parasitic infections. They contain granules that stain red-orange with eosin.

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Macrophage

A large phagocytic cell that engulfs and destroys foreign invaders like bacteria, viruses, and cellular debris.

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Cryptococcus neoformans

A type of fungus that can cause infections in the lungs, brain, and other organs, especially in people with weakened immune systems.

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Candida albicans

A type of yeast that is normally present in the body but can cause infection, especially in the mouth, vagina, or skin, called candidiasis.

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What kind of cells are involved with allergic responses?

Eosinophils are a type of white blood cell that are specifically involved in allergic reactions.

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Bence Jones protein

A type of abnormal protein found in the urine of patients with multiple myeloma, a cancer of plasma cells. It is characterized by its unique property of dissolving at 100°C and coagulating at 40-60°C.

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Bence Jones protein: Dissolving and coagulating

Bence Jones protein dissolves at 100°C (boiling point) and coagulates at 40-60°C (body temperature). This unusual temperature behavior distinguishes it from other proteins.

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Bence Jones protein: Presence in urine

Bence Jones protein is primarily found in the urine of patients with multiple myeloma, a cancer of plasma cells. It is a sign of the disease and its presence can aid in diagnosis.

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Bence Jones protein: Significance

The presence of Bence Jones protein in urine is a significant indicator of multiple myeloma, a type of cancer. Its detection can aid in diagnosis and monitoring of treatment progress.

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Bence Jones protein: Diagnostic tool

Bence Jones protein can be used as a diagnostic tool for multiple myeloma. By detecting its presence in urine, doctors can identify the disease and monitor the effectiveness of treatments.

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Urates in Heat

Urates are soluble in heat, meaning they dissolve when heated.

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Urine Volume

The normal volume of urine produced daily is approximately 1000-1500 mL.

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Organic Components in Urine

Urea, creatinine, uric acid, and hippuric acid are examples of organic substances found in urine.

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Inorganic Components in Urine

Inorganic compounds like chloride, sodium, potassium, sulfate, phosphate, ammonium, magnesium, and calcium are present in urine.

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Urea - the main organic compound in urine

Urea is the major organic component in urine.

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Tubular Casts

Microscopic cylindrical structures formed in the renal tubules, composed of cellular debris, proteins, or other substances. They help diagnose kidney disease.

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Red Blood Cell Casts

Tubular casts containing red blood cells, indicating blood in the renal tubules, commonly associated with glomerulonephritis.

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White Blood Cell Casts

Casts containing white blood cells, suggesting inflammation or infection in the renal tubules.

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Granular Casts

Casts with a granular appearance, representing cellular debris or protein breakdown products, commonly seen in chronic kidney disease.

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Waxy Casts

Casts having a waxy appearance, indicating significant kidney damage and a poor prognosis.

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Study Notes

Urine Analysis Review Questions

  • Urine Composition: Urine is primarily composed of 95% water and 5% solutes.
  • Normal Urine Color: Normal urine color ranges from straw to amber.
  • Urochrome: A pigment that imparts a yellow color to urine.
  • Urobilinogen: An inactive, colorless oxidation product of urobilin. Oxidation of urobilinogen to urobilin imparts an orange-brown color to stale urine.
  • Urobilin: An orange-brown oxidation product of urobilinogen that is important in urine color.
  • Uroerythrin: A pink pigment most evident in urine samples that aren't fresh.
  • Preservation: Refrigeration is the most common method of urine preservation.
  • Daily Urine Output: Normal daily urine output is 600-2,500 mL.
  • Polyuria: Excessive urine output. This can be associated with diabetes insipidus or diabetes mellitus.
  • Oliguria: Decreased urine output.
  • Anuria: Complete cessation of urine output.
  • Dysuria: Painful urination. This can be caused by Urinary Tract Infection (UTI).
  • Nocturia: Increased urination during the night.
  • Urine Color and Associated Conditions: Various urine colors(e.g., pale yellow, amber, green, red, brown, black) may be indicative of particular conditions or intake of certain substances.
  • Specific Gravity: A measure indicating urine concentration. Higher values point to concentration; lower values indicate dilution.
  • Normal Specific Gravity: Normal range is 1.002 – 1.040..
  • Clinical Significance of Urine Constituents: Urine analysis determines the presence and amount of various substances (e.g., protein, glucose, blood) or detects abnormal conditions affecting the urinary system.

Clinical Microscopy Review Questions

  • Clinical Significance of Urine Constituents: Urine analysis helps assess potential health issues by identifying abnormal components.
  • Causes of abnormal urine colors: Various conditions, substances, or foods may cause changes in urine color.
  • Abnormal urine color interpretation: Specific urine colors (e.g., blue-green, orange, pink, brown, black) may reflect conditions or substances ingested..
  • Normal Values or Ranges: It is expected that values in urine analysis should fall within normal ranges.

Additional Topics (from provided text)

  • Clinical Microscopy MTAP 100 Review Questions: This section covers various questions related to the analysis of urine and other body fluids for clinical purposes.
  • Renal blood flow and glomerular filtration: These are part of normal urine formation processes.
  • Normal urine pH: Normal urine pH is 4.5–8.0.
  • Other Urine Analysis Topics: The text includes multiple other topics related to testing characteristics or conditions linked to urine analytes or conditions based on the urine analysis.

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