Urinary Tract Infection Case Study
67 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary cause of urinary tract infections?

  • Fungal infections due to prolonged antibiotic use
  • Chemical irritation from medications
  • Viral infections from the respiratory tract
  • Bacteria from gut flora (correct)

Which of the following describes an uncomplicated urinary tract infection?

  • Is associated with immunocompromised patients
  • Is mild and affects individuals with a normal urinary tract (correct)
  • Is severe and leads to hospitalization
  • Occurs in individuals with urinary tract abnormalities

What is one potential consequence of a urinary tract infection in the elderly patient described?

  • Improved renal function
  • Increased risk of stroke
  • Decreased urinary frequency
  • Sepsis (correct)

Which antibiotic was prescribed for the urinary tract infection in the case study?

<p>Co-trimoxazole (A)</p> Signup and view all the answers

What is a common clinical manifestation of a urinary tract infection?

<p>Dark yellow-orange urine with a strong odor (D)</p> Signup and view all the answers

Why is the patient at an increased risk for developing a urinary tract infection?

<p>He is using a Foley catheter and has diabetes (C)</p> Signup and view all the answers

What condition is NOT typically associated with a complicated urinary tract infection?

<p>Normal urinary tract function (B)</p> Signup and view all the answers

What are the two components of co-trimoxazole?

<p>Sulfamethoxazole and trimethoprim (A)</p> Signup and view all the answers

What is the recommended duration of antibiotic therapy for uncomplicated urinary tract infections (UTIs)?

<p>3-7 days (C)</p> Signup and view all the answers

Which of the following antibiotics is the first choice for the initial treatment of a urinary tract infection?

<p>Trimethoprim (A)</p> Signup and view all the answers

What is a recommended fluid intake for patients with urinary tract infections?

<p>2 L/day (A)</p> Signup and view all the answers

What role do Tamm-Horsfall proteins play in the urinary tract?

<p>They are bactericidal agents secreted by tubular cells. (C)</p> Signup and view all the answers

In a patient with a urinary tract infection receiving intravenous heparin, which antibiotic was ordered for treatment?

<p>Co-trimoxazole (D)</p> Signup and view all the answers

Which of the following is a common mechanism that allows bacteria to cause a urinary tract infection (UTI)?

<p>Access to the urinary tract followed by overwhelming host defenses. (B)</p> Signup and view all the answers

Which of the following is a potential complication regarding antibiotic choice in a diabetic patient with a UTI?

<p>Increased blood sugar levels (D)</p> Signup and view all the answers

Which condition is associated with an increased risk of urinary tract infection due to impaired bladder function?

<p>Spinal cord injury (B)</p> Signup and view all the answers

Which urinary symptom might indicate a urinary tract infection as per the presented case study?

<p>Cloudy and dark yellow-orange urine with a strong odor (C)</p> Signup and view all the answers

What additional management option is suggested for patients experiencing symptoms of a urinary tract infection?

<p>Urinary alkalinising agent (D)</p> Signup and view all the answers

What is the most common causative organism of acute cystitis?

<p>Escherichia coli (B)</p> Signup and view all the answers

Which of the following factors contributes to the risk of developing a urinary tract infection in elderly patients?

<p>Dehydration (D)</p> Signup and view all the answers

What factor allows E. coli to resist being flushed from the urinary tract during micturition?

<p>Fimbriae that bind to uroepithelial receptors. (A)</p> Signup and view all the answers

Which host group is NOT associated with an increased risk of UTIs?

<p>Athletes engaging in high-intensity sports (B)</p> Signup and view all the answers

Which type of UTI is characterized by inflammation of the kidney and may result from ascending infection?

<p>Acute pyelonephritis (D)</p> Signup and view all the answers

What is one effect of low pH in the urine regarding urinary tract infections?

<p>It inhibits microbial activity. (D)</p> Signup and view all the answers

What is a common clinical feature of acute cystitis?

<p>Frequent urination (C)</p> Signup and view all the answers

Which organism is most commonly associated with acute pyelonephritis?

<p>E.coli (D)</p> Signup and view all the answers

What does a classic triad of symptoms in acute pyelonephritis include?

<p>Loin pain, fever, tenderness over the kidney (A)</p> Signup and view all the answers

Which condition is characterized by sloughing of the bladder mucosa?

<p>Ulcerative cystitis (A)</p> Signup and view all the answers

What is the most common risk factor for pyelonephritis?

<p>Renal stones (C)</p> Signup and view all the answers

What is a notable feature of chronic pyelonephritis?

<p>Asymptomatic initially (C)</p> Signup and view all the answers

What symptom is typically absent in acute cystitis?

<p>Fever (A)</p> Signup and view all the answers

What investigation is essential before starting antibiotic therapy for urinary infections?

<p>Urine culture and antibiotic sensitivity (C)</p> Signup and view all the answers

What is a common symptom of bladder wall necrosis in gangrenous cystitis?

<p>Hemorrhage (D)</p> Signup and view all the answers

Which clinical feature is associated with strangury in acute cystitis?

<p>Intense desire to pass urine after micturition (C)</p> Signup and view all the answers

Which of the following factors is NOT a risk factor for developing a urinary tract infection in the described patient?

<p>Regular exercise (B)</p> Signup and view all the answers

What is a common characteristic of a complicated urinary tract infection?

<p>It involves abnormalities in the urinary tract (D)</p> Signup and view all the answers

Why might co-trimoxazole have been chosen for treating the urinary tract infection in this patient?

<p>It has a broad spectrum against common UTI bacteria (B)</p> Signup and view all the answers

Which of the following correctly reflects a clinical manifestation of urinary tract infection?

<p>Cloudy, foul-smelling urine (A)</p> Signup and view all the answers

What potential drug interaction should be monitored in a patient receiving co-trimoxazole?

<p>Interaction with antidiabetic medications (A)</p> Signup and view all the answers

Which condition could contribute to the patient's complicated urinary tract infection?

<p>Obstructive uropathy (D)</p> Signup and view all the answers

Which of the following best describes the origin of bacteria causing urinary tract infections?

<p>Bacteria from gut flora (D)</p> Signup and view all the answers

What is the typical appearance of urine in a patient with a urinary tract infection?

<p>Cloudy and dark yellow-orange (B)</p> Signup and view all the answers

What is a primary host defense mechanism that helps prevent urinary tract infections?

<p>High concentration of urea in urine (D)</p> Signup and view all the answers

Which bacterial factor is associated with the ability to resist phagocytosis?

<p>Capsular antigens (C)</p> Signup and view all the answers

Which of the following conditions significantly increases the risk of developing a urinary tract infection?

<p>Urinary retention due to neurologic impairment (C)</p> Signup and view all the answers

Acute cystitis is most commonly caused by which organism?

<p>Escherichia coli (D)</p> Signup and view all the answers

Which type of UTI is characterized by inflammation of the urinary bladder?

<p>Acute cystitis (C)</p> Signup and view all the answers

What structural feature of the male urinary system contributes to a lower incidence of UTIs compared to females?

<p>Longer urethra (C)</p> Signup and view all the answers

Which of the following best describes a key pathogenic mechanism utilized by bacteria in the urinary tract?

<p>Binding to uroepithelium via fimbriae (B)</p> Signup and view all the answers

Which additional factor is a known contributor to the incidence of urinary tract infections in postmenopausal women?

<p>Decreased vaginal flora protection (C)</p> Signup and view all the answers

Which antibiotic is specifically noted as the choice for initial treatment of urinary tract infections?

<p>Trimethoprim (B)</p> Signup and view all the answers

What additional management option is suggested for symptom relief in patients with urinary tract infections?

<p>Urinary alkalinising agent (A)</p> Signup and view all the answers

Which of the following antibiotics is NOT listed as an option for treating urinary tract infections?

<p>Vancomycin (B)</p> Signup and view all the answers

What symptom might indicate a more severe urinary tract infection in the case study patient?

<p>Cloudy and dark yellow-orange urine (B)</p> Signup and view all the answers

In the case provided, what underlying condition is likely contributing to the patient's susceptibility to urinary tract infections?

<p>Type 2 diabetes (C)</p> Signup and view all the answers

Which antibiotic regimen includes a combination of sulfamethoxazole and trimethoprim?

<p>Co-trimoxazole (A)</p> Signup and view all the answers

What is the expected daily fluid intake recommended for patients with urinary tract infections?

<p>2 L/day (D)</p> Signup and view all the answers

What indicates gangrenous cystitis?

<p>Necrosis of the bladder wall (A)</p> Signup and view all the answers

Which clinical feature is least likely to be experienced by a patient with acute pyelonephritis?

<p>Cloudy urine (C)</p> Signup and view all the answers

What is the most common complication of prolonged urinary tract infection?

<p>Ulcerative cystitis (D)</p> Signup and view all the answers

Which of the following is a common risk factor for chronic pyelonephritis?

<p>Urinary obstruction (C)</p> Signup and view all the answers

What is indicated by the presence of proteinuria during routine checks?

<p>Chronic pyelonephritis (D)</p> Signup and view all the answers

Which causative organism is most commonly associated with acute pyelonephritis?

<p>E. coli (C)</p> Signup and view all the answers

What is a notable symptom associated with the inflamed bladder wall in acute cystitis?

<p>Strangury (A)</p> Signup and view all the answers

Which laboratory test is essential before the initiation of antibiotic therapy for urinary infections?

<p>Urine culture (C)</p> Signup and view all the answers

What type of cystitis is characterized by pus and suppurative exudates?

<p>Suppurative cystitis (A)</p> Signup and view all the answers

What is a common presentation of chronic renal failure associated with chronic pyelonephritis?

<p>Fatigue and tiredness (B)</p> Signup and view all the answers

Flashcards

Urinary Tract Infection (UTI)

Inflammation of the urinary tract's lining, usually caused by bacteria from the gut.

Uncomplicated UTI

Mild UTI with no noticeable complications, affecting a normal urinary tract.

Complicated UTI

UTIs with abnormalities in the urinary tract or associated with conditions like weakened immune systems.

Risk factors for UTI

Factors that increase the chances of developing a urinary tract infection, including weakened immune system, pre-existing conditions in the urinary tract and others.

Signup and view all the flashcards

Urethritis

Inflammation of the urethra, a part of the urinary tract.

Signup and view all the flashcards

Cystitis

Infection of the bladder, part of the urinary tract.

Signup and view all the flashcards

Pyelonephritis

Infection of one or both kidneys, part of the urinary tract.

Signup and view all the flashcards

Prostatitis

Inflammation of the prostate gland, a male reproductive organ.

Signup and view all the flashcards

UTI Host Defence Mechanisms

Body's natural defenses against UTIs (e.g., flushing with urination, urine acidity, proteins that kill bacteria).

Signup and view all the flashcards

Bacterial Factors in UTIs

Bacterial traits that promote infection (e.g., capsules preventing phagocytosis, enzymes damaging tissue).

Signup and view all the flashcards

Host Groups at Risk for UTIs

Individuals with conditions increasing UTI risk (e.g., kidney stones, diabetes, pregnancy, weakened immune system).

Signup and view all the flashcards

Acute Cystitis

Inflammation of the bladder, a common type of UTI.

Signup and view all the flashcards

Escherichia coli (E. coli)

The most common bacteria causing UTIs.

Signup and view all the flashcards

Neurogenic Bladder

Inability to properly empty the bladder, increasing UTI risk due to residual urine.

Signup and view all the flashcards

Mechanism of UTI

Process of bacteria entering the urinary tract, overcoming defenses, and traveling upward.

Signup and view all the flashcards

Antibiotic Regimen for UTI

A set of antibiotics prescribed to treat a UTI. Choices include Trimethoprim, Nitrofurantoin, Quinolones, Cefalexin, Co-amoxiclav, and Amoxicillin.

Signup and view all the flashcards

Trimethoprim

A common first-line antibiotic for treating UTIs.

Signup and view all the flashcards

Symptoms of UTI

Cloudy, dark yellow-orange urine with a strong odor; often accompanied by pain or burning during urination.

Signup and view all the flashcards

Duration of UTI Therapy

The time period for which antibiotics are administered to treat a UTI, depending on the severity (uncomplicated vs. complicated).

Signup and view all the flashcards

Acute Pyelonephritis

A sudden, serious infection of the upper urinary tract characterized by loin pain, fever, and tenderness over the kidney.

Signup and view all the flashcards

Chronic Pyelonephritis

A persistent infection of the kidneys, often due to obstructions like kidney stones or vesicoureteral reflux, leading to scarring and gradual loss of kidney function.

Signup and view all the flashcards

Risk Factors (Pyelonephritis)

Conditions that increase the chance of getting a kidney infection such as kidney stones and vesicoureteral reflux; pregnancy, neurogenic bladder, and instrumentation.

Signup and view all the flashcards

Causative Organisms (Acute Pyelonephritis)

Common types of bacteria that lead to acute infections of the upper urinary tracts.

Signup and view all the flashcards

Prolonged Infection (Cystitis)

Infections that last for an extended period of time, leading to conditions like ulceration and necrosis of the bladder lining.

Signup and view all the flashcards

Diffuse Haemorrhage

A type of bleeding inside the bladder.

Signup and view all the flashcards

Urine Culture

Laboratory test to identify the bacteria causing a urinary infection and checking sensitivity to antibiotics.

Signup and view all the flashcards

Vesicoureteral Reflux

A condition where urine flows back from the bladder into the ureters (tubes connecting the bladder to the kidneys).

Signup and view all the flashcards

UTI Defense: Micturition

The act of peeing helps flush out bacteria, preventing UTI.

Signup and view all the flashcards

UTI Defense: Urine pH

The urine's acidity makes it difficult for bacteria to survive.

Signup and view all the flashcards

UTI Defense: Tamm-Horsfall Proteins

These proteins, secreted by kidney cells, directly kill bacteria.

Signup and view all the flashcards

UTI Defense: Vesico-ureteric Junction

This valve prevents urine from flowing back up into the kidneys.

Signup and view all the flashcards

UTI Cause: Bacterial Capsules

Some bacteria have protective capsules that shield them from the body's defenses.

Signup and view all the flashcards

UTI Cause: Haemolysin

This bacterial enzyme damages the lining of the urinary tract, increasing infection risk.

Signup and view all the flashcards

UTI Cause: Urease Bacteria

These bacteria produce urease, an enzyme that makes the urine less acidic, making it easier for bacteria to grow.

Signup and view all the flashcards

UTI Cause: E. coli Fimbriae

These hair-like structures help E. coli bind to the bladder lining, resisting flushing during urination.

Signup and view all the flashcards

UTI Pathophysiology

An inflammation of the urinary epithelium usually triggered by bacteria from the gut flora. It can affect any part of the urinary tract, including the urethra, prostate, bladder, ureter, and kidneys.

Signup and view all the flashcards

UTI Risk Factors

Conditions that increase the likelihood of getting a UTI, including things like a weakened immune system, pre-existing urinary tract conditions, and catheters.

Signup and view all the flashcards

UTI Treatment

Antibiotics are the primary treatment for UTI. The specific antibiotic and duration of treatment depends on the severity and type of UTI.

Signup and view all the flashcards

Co-trimoxazole | UTI Treatment

Co-trimoxazole, a combination of sulfamethoxazole and trimethoprim, is often used for UTI treatment. It targets the bacteria causing the infection, helping the body fight it off.

Signup and view all the flashcards

Drug Interactions | Co-trimoxazole

Co-trimoxazole can interact with other medications. It's important to discuss all medications with your doctor before taking co-trimoxazole.

Signup and view all the flashcards

UTI Symptoms

Symptoms can include frequent urination, pain or burning during urination, cloudy and dark yellow-orange urine with a strong odor, fever, and back pain.

Signup and view all the flashcards

What is a UTI?

A urinary tract infection (UTI) is an inflammation of the urinary tract's lining, usually caused by bacteria from the gut. It can affect the urethra, bladder, ureters, or kidneys.

Signup and view all the flashcards

What's an Uncomplicated UTI?

An uncomplicated UTI is a mild UTI with no noticeable complications, affecting a normal urinary tract.

Signup and view all the flashcards

What's a Complicated UTI?

A complicated UTI is an infection that affects a urinary tract with pre-existing abnormalities or conditions like a weakened immune system.

Signup and view all the flashcards

What's the main antibiotic for UTIs?

Trimethoprim is the first choice antibiotic for initial treatment of UTIs.

Signup and view all the flashcards

What are other UTI antibiotic options?

Besides trimethoprim, other antibiotics used for UTIs include nitrofurantoin, quinolone antibiotics like ciprofloxacin and norfloxacin, cefalexin, co-amoxiclav, and amoxicillin.

Signup and view all the flashcards

How long is UTI treatment?

For uncomplicated UTIs, antibiotic treatment usually lasts 3-7 days. For complicated UTIs, treatment typically lasts 7-14 days.

Signup and view all the flashcards

What are the symptoms of UTI?

Common symptoms of a UTI include cloudy, dark yellow-orange urine with a strong odor, and pain or burning during urination.

Signup and view all the flashcards

What are the risk factors for UTIs?

Factors that increase the risk of developing a UTI include weakened immune system, pre-existing conditions in the urinary tract, having a Foley catheter, and being elderly.

Signup and view all the flashcards

What are some causes of acute cystitis?

Acute cystitis is often caused by Escherichia coli bacteria. It can also be caused by other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis. Certain factors like sexual intercourse, urinary catheters, and diabetes can increase the risk of infection.

Signup and view all the flashcards

What are the clinical features of acute pyelonephritis?

Acute pyelonephritis presents with a classic triad of symptoms: loin pain, fever, and tenderness over the kidney. Other symptoms may include urinary frequency, dysuria, and chills.

Signup and view all the flashcards

What is the pathology of acute pyelonephritis?

Acute pyelonephritis involves progressive infection of the upper urinary tract. This leads to inflammation, fibrosis, and scarring of the renal pelvis and surrounding tissues. Small cortical abscesses and streaks of pus may be present in the medulla.

Signup and view all the flashcards

What is the most common risk factor for pyelonephritis?

Renal stones and vesicoureteral reflux are the most common risk factors for pyelonephritis. Other factors include pregnancy, neurogenic bladder, and instrumentation.

Signup and view all the flashcards

What are the possible complications of prolonged cystitis?

Prolonged cystitis can lead to several complications. Diffuse hemorrhage (haemorrhagic cystitis) may occur with bleeding within the bladder. Pus or suppurative exudates (suppurative cystitis) can also form. In severe cases, the bladder mucosa may slough off, resulting in ulceration (ulcerative cystitis). The most extreme complication involves necrosis of the bladder wall (gangrenous cystitis).

Signup and view all the flashcards

How do I collect a urine sample for a urine culture?

A urine specimen for a urine culture should be collected before starting any antibiotic therapy. This is important to ensure accurate identification of the causative organism and its sensitivity to antibiotics.

Signup and view all the flashcards

What is chronic pyelonephritis?

Chronic pyelonephritis, also known as reflux nephropathy, is often associated with urinary obstructions like renal stones and vesicoureteral reflux. It involves persistent or recurrent kidney infection leading to scarring. This condition typically has a gradual onset with fatigue, tiredness, and may be asymptomatic initially, but can eventually lead to chronic renal failure.

Signup and view all the flashcards

What are the investigations for suspected UTIs?

Routine investigations for UTIs involve a urine dipstick test, urine microscopy, and urine culture with antibiotic sensitivity testing. Additionally, imaging tests like ultrasound or CT scans may be used to identify any underlying urinary obstruction.

Signup and view all the flashcards

What are some common causal organisms for acute pyelonephritis?

Acute pyelonephritis is commonly caused by bacteria like E. coli, Proteus, and Pseudomonas.

Signup and view all the flashcards

What is the typical duration of UTI therapy?

The duration of UTI therapy depends on the severity of the infection. Uncomplicated UTIs can be treated with shorter antibiotic courses, while complicated UTIs often require longer courses.

Signup and view all the flashcards

Study Notes

Urinary Tract Infection (UTI)

  • UTI is an inflammation of the urinary epithelium, typically caused by bacteria from the gut flora.
  • UTIs can develop anywhere along the urinary tract, including the urethra (urethritis), prostate (prostatitis), bladder (cystitis), ureter, and kidneys (pyelonephritis).

Learning Outcomes

  • Describe the pathophysiology of urinary tract infections.
  • Discuss the clinical manifestations and antibiotic regimens for urinary tract infections.

Case Study

  • A 75-year-old male patient admitted for a stroke two days prior, developed a urinary tract infection.
  • The patient had a Foley catheter draining cloudy, dark yellow-orange urine with a strong odour.
  • He was receiving intravenous heparin.
  • The patient had a history of type 2 diabetes.
  • The physician ordered co-trimoxazole for the UTI.
  • Identify risk factors for UTI in this patient.
  • Determine potential drug interactions.
  • Explain the antibiotic choice.

Spectrum of UTI

  • Uncomplicated UTI: Mild, no complications in individuals with normal urinary tracts.
  • Complicated UTI: Abnormalities in the urinary tract, or immunocompromised individuals (e.g., HIV, renal transplant, diabetes, spinal cord injuries).

Pathophysiology of UTI

  • The urinary tract is normally sterile.
  • Several mechanisms protect the urinary tract from ascending bacterial infections.
  • UTI occurs when bacteria gain access, overwhelm the defenses, and ascend.

Host Defence Mechanisms

  • Most bacteria are flushed from the urethra during urination.
  • Urine's low pH inhibits bacterial growth.
  • High urea concentration in urine is toxic to bacteria.
  • Tamm-Horsfall proteins, secreted by tubular cells, are bactericidal.
  • Closure of the vesico-ureteric junction prevents reflux into the ureters.
  • Prostatic secretions and a longer urethra in males contribute to defense.

Mechanisms of UTI: Bacterial and Host Factors

  • Bacterial factors:
    • Capsules resist phagocytosis.
    • Haemolysins damage the epithelium.
    • Urease-positive bacteria (e.g., Proteus and Klebsiella) promote infection.
    • E. coli fimbriae bind to receptors and resist flushing.
  • Host factors:
    • Kidney stones.
    • Diabetes.
    • Immunosuppression.
    • Ureteral reflux.
    • Pregnancy.
    • Neurogenic bladder.
    • Prostatic hypertrophy.
    • Short urethra in women.
    • Indwelling catheters.
    • E. coli contamination from the colon.

Host Groups for UTI

  • Renal stones
  • Diabetes
  • Immunosuppression
  • Pregnancy
  • Postmenopausal women
  • Neurogenic bladder (neurologic impairment interferes with normal bladder contraction; residual urine and ascending infection)
  • Catheterization
  • Shorter urethra in women

Types of UTI

  • Acute cystitis
  • Acute pyelonephritis
  • Chronic pyelonephritis

Acute Cystitis

  • Inflammation of the urinary bladder.
  • Most common site of UTI.
  • Causal organisms:
    • Escherichia coli (most common).
    • Staphylococcus saprophyticus (second most common).
    • Klebsiella, Proteus, Pseudomonas, fungi, viruses, parasites (less common).

Different Types of Acute Cystitis

  1. Hyperemic mucosa in mild inflammation
  2. Advanced cases (diffuse haemorrhage; suppurative exudates)
  3. Prolonged infection (sloughing of bladder mucosa with ulcer formation)
  4. Severe infections (necrosis of bladder wall)

E. coli

  • A common bacterium causing UTIs. (Image of E. coli)

Clinical Features of Acute Cystitis

  • Acute onset.
  • Frequent urination.
  • Urgency
  • Dysuria (pain during urination).
  • Suprapubic pain during and after voiding.
  • Intense desire to urinate.
  • Cloudy urine with an unpleasant odour.
  • Microscopic or visible haematuria.
  • Mild systemic symptoms.

Pyelonephritis

  • Infection of the upper urinary tracts (ureters, renal pelvis, interstitium).
  • Can be acute or chronic.
  • Risk factors:
    • Renal stones
    • Vesicoureteral reflux
    • Pregnancy
    • Neurogenic bladder
    • Instrumentation

Acute Pyelonephritis

  • Usually due to instrumentation or urinary tract surgery.
  • May result from a blood-borne infection.
  • Causal organisms:
    • E. coli
    • Proteus
    • Pseudomonas

Pathology of Acute Pyelonephritis

  • Progressive infection leading to inflammation, fibrosis, and scarring.
  • Acutely inflamed renal pelvis with small cortical abscesses and streaks of pus in the medulla.

Clinical Features of Acute Pyelonephritis

  • Acute onset.
  • Classic triad: loin pain, fever, tenderness over the kidney.
  • Urinary frequency.
  • Dysuria.

Chronic Pyelonephritis

  • Usually associated with urinary obstructions (e.g., renal stones, vesicoureteral reflux).
  • Persistent or recurrent kidney infections result in scarring.
  • Gradual onset with tiredness, fatigue.
  • Often asymptomic initially.
  • Hypertension and proteinuria (routine check-ups).
  • Progressive deterioration in renal function.
  • Symptoms of chronic renal failure.

Investigations

  • Urine dipstick test.
  • Urine microscopy.
  • Urine culture with antibiotic sensitivity testing.
  • Urine specimen collection before antibiotic initiation.
  • Identify risk factors (imaging to detect urinary obstructions: e.g., X-ray, USG, CT).

Management

  • Antibiotics for all cases of confirmed UTI.
  • Duration of therapy:
    • Uncomplicated UTI: 3-7 days.
    • Complicated UTI: 7-14 days.
  • Fluid intake of at least 2 liters per day.
  • Urinary alkalinizing agent (potassium citrate) for symptomatic relief.

Antibiotic Regimens for UTI

  • Trimethoprim: Initial treatment choice.
  • Other antibiotics:
    • Nitrofurantoin
    • Quinolone antibiotics (e.g., ciprofloxacin, norfloxacin)
    • Cefalexin
    • Co-amoxiclav
    • Amoxicillin

Antibiotic Regimens for UTI (Table)

  • (Table of antibiotic regimens - included from the original document)

Key Terms

  • Urinary tract infection (UTI)
  • Cystitis
  • Pyelonephritis
  • Antibiotic regimens for UTI

Additional Information (from provided text)

  • Specific antibiotic dosages and durations are available in a table, which can be added to the notes.
  • Important note for potential complications of prolonged infection are mentioned in different areas of the notes..

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

Description

This quiz explores the various aspects of Urinary Tract Infections (UTIs), focusing on their pathophysiology, clinical manifestations, and treatment options. Through a case study involving a 75-year-old male patient, participants will analyze risk factors, potential drug interactions, and antibiotic selections. Dive into the complexities of UTIs in an engaging and informative manner.

More Like This

Use Quizgecko on...
Browser
Browser