Podcast
Questions and Answers
What is a recommended component of a brief intervention for smoking cessation?
What is a recommended component of a brief intervention for smoking cessation?
Which healthcare professional has been shown to be effective in providing interventions for smoking cessation?
Which healthcare professional has been shown to be effective in providing interventions for smoking cessation?
What is an example of a more intensive, proactive support for smoking cessation?
What is an example of a more intensive, proactive support for smoking cessation?
What is a key aspect of a smoking cessation program in a community pharmacy setting?
What is a key aspect of a smoking cessation program in a community pharmacy setting?
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What is a recommended strategy for promoting health behaviors in a community pharmacy setting?
What is a recommended strategy for promoting health behaviors in a community pharmacy setting?
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What is a key aspect of a smoking cessation program in a dental setting?
What is a key aspect of a smoking cessation program in a dental setting?
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What is a recommended approach for promoting smoking cessation in primary care settings?
What is a recommended approach for promoting smoking cessation in primary care settings?
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What is a key aspect of a smoking cessation program in a nursing setting?
What is a key aspect of a smoking cessation program in a nursing setting?
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What happens to CYP450 activity when a person stops smoking?
What happens to CYP450 activity when a person stops smoking?
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What should be done under medical supervision when a patient stops smoking and is taking clozapine?
What should be done under medical supervision when a patient stops smoking and is taking clozapine?
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What is the target percentage reduction in clozapine dose when a patient stops smoking?
What is the target percentage reduction in clozapine dose when a patient stops smoking?
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How long should blood and clinical monitoring be continued after smoking cessation in a patient taking clozapine?
How long should blood and clinical monitoring be continued after smoking cessation in a patient taking clozapine?
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What is the purpose of Therapeutic Drug Monitoring (TDM) in patients taking clozapine who stop smoking?
What is the purpose of Therapeutic Drug Monitoring (TDM) in patients taking clozapine who stop smoking?
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What is an example of a pharmacotherapy for smoking cessation?
What is an example of a pharmacotherapy for smoking cessation?
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What is the name of the algorithm used for pharmacotherapy treatment of smoking cessation?
What is the name of the algorithm used for pharmacotherapy treatment of smoking cessation?
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Which organization provides clinical guidelines for smoking cessation?
Which organization provides clinical guidelines for smoking cessation?
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What is a key consideration when using bupropion for smoking cessation?
What is a key consideration when using bupropion for smoking cessation?
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What is a benefit of using NRT with other smoking cessation therapies?
What is a benefit of using NRT with other smoking cessation therapies?
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What is an important aspect of assessing smoking cessation treatment?
What is an important aspect of assessing smoking cessation treatment?
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What is a fast-acting product that can be used when strong cigarette cravings occur?
What is a fast-acting product that can be used when strong cigarette cravings occur?
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What is a key role of healthcare professionals in smoking cessation?
What is a key role of healthcare professionals in smoking cessation?
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What is a harm reduction strategy in smoking cessation?
What is a harm reduction strategy in smoking cessation?
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Study Notes
Smoking Cessation
- Offer every smoker at least a brief intervention for smoking cessation, including:
- Simple opportunistic advice to consider quitting
- An assessment of the smoker's commitment to quit
- Offer of pharmacotherapy and/or behavioural support
- Self-help material
- Referral to more intensive, proactive support
Healthcare Professional Interventions
- Physician advice for smoking cessation is effective
- Community pharmacy personnel can provide interventions for smoking cessation
- Dental setting interventions can also be effective for smoking cessation
- Nursing interventions can support smoking cessation efforts
Antipsychotics and Smoking
- Smoking cessation can lead to rapid exponential decrease in CYP450 activity, increasing clozapine blood levels and potentially causing toxic effects
- Under medical supervision, clozapine dose should be decreased immediately upon cessation of smoking (about 10% daily, up to 50% reduction)
- TDM, blood, and clinical monitoring are necessary for up to 6 months
Pharmacotherapy
- Nicotine Replacement Therapy (NRT) is an option for smoking cessation
- Varenicline and Bupropion are also pharmacotherapy options
- Pharmacotherapy treatment algorithm should be followed
- Use of NRT with other medications can improve effectiveness
- Bupropion can cause false-positive results with some urine drug screens
Key Points
- Assess progress throughout treatment and stop drug if there is no marked reduction in smoking
- Use pharmacotherapy in combination with other support methods for optimal results
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