8 Questions
Which of the following is the most frequent cause of oxidative phosphorylation disorders?
Complex I deficiency
What is the outcome of progressive encephalomyopathies caused by complex I deficiency?
Fatal outcome
What is the role of FMN in complex I?
It takes 2 electrons from NADH
Which of the following best describes the function of FMNH2 in complex I?
It sends 2 electrons one at a time to Fe-S centers
Where do the electrons go to from FMNH2 in complex I?
They are delivered to the mobile carrier
What is the current status of a cure for complex I deficiency?
There is no known cure
What percentage of cases of complex I deficiency are currently unexplained?
50%
What is the wire in complex I?
Fe-S centers
Test your knowledge on Complex I Deficiency, a common cause of oxidative phosphorylation disorders. Learn about the diverse clinical symptoms and fatal outcomes associated with this disease. Explore the current understanding of disease-causing mutations and uncover the mysteries behind the unexplained cases. Take this quiz to deepen your understanding of complex 1 deficiency.
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