Understanding Respiratory Tract Infections
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Questions and Answers

Inflammatory exudates and hemorrhages are more common in ______ infections

bacterial

Vesicles and ulcerated lesions are more common in ______ diseases

viral

Pharyngeal pseudomembranes are associated with ______

diphtheria

Oral and pharyngeal lesions are accentuated in ______ hosts

<p>immunocompromised</p> Signup and view all the answers

Neisseria gonorrhoeae is now considered a pharyngeal pathogen usually transmitted by ______ contact

<p>oral–genital</p> Signup and view all the answers

Most pneumonias in infants and children are caused by ______.

<p>viral infections</p> Signup and view all the answers

The most common cause of acute bacterial pneumonia is ______.

<p>Pneumococcus</p> Signup and view all the answers

Gram-negative pneumonias are typically found in ______ hosts.

<p>debilitated</p> Signup and view all the answers

Acute pneumonia can be caused by the ______ virus, especially in infants and the elderly.

<p>respiratory syncytial</p> Signup and view all the answers

Mycobacterium tuberculosis is associated with ______ pneumonia.

<p>chronic</p> Signup and view all the answers

Direct antigen tests for rapidly detecting the group A antigen in ______ swabs have gained popularity.

<p>throat</p> Signup and view all the answers

These tests are rapid and very specific when positive but only about ______% sensitive.

<p>90</p> Signup and view all the answers

Negative results must be confirmed by ______ before withholding treatment.

<p>culture</p> Signup and view all the answers

For the laboratory diagnosis of diphtheria or pharyngeal ______, clinical suspicion should be indicated.

<p>gonorrhea</p> Signup and view all the answers

Candida species and Pseudomonas species are often found in pharyngeal or oral specimens from healthy ______.

<p>individuals</p> Signup and view all the answers

Other bacterial pathogens such as Streptococcus pneumoniae and Staphylococcus aureus may be present in the ______.

<p>pharynx</p> Signup and view all the answers

The laboratory diagnosis of causes of peritonsillar and retropharyngeal abscesses is based on ______ staining and culture.

<p>Gram</p> Signup and view all the answers

The middle respiratory tract includes the epiglottis, larynx, trachea, and ______.

<p>bronchi</p> Signup and view all the answers

A major bacteriologic consideration in acute bronchitis is ______.

<p>Bordetella pertussis</p> Signup and view all the answers

The percentage of acute tracheitis caused by viruses is ______%.

<p>90</p> Signup and view all the answers

The processes of collecting acute and convalescent sera can help determine the antibody response to ______.

<p>common respiratory viruses</p> Signup and view all the answers

In bacterial infections, the examination of nasopharyngeal smears or aspirates is useful in establishing the ______.

<p>diagnosis</p> Signup and view all the answers

When purulent sputum is produced, ______ staining can be useful.

<p>Gram</p> Signup and view all the answers

Lower respiratory tract infection involves invasion and disease of the lung, including the alveolar spaces and their supporting structure, the ______.

<p>interstitium</p> Signup and view all the answers

Acute bronchitis is often assessed through deep nasopharyngeal cultures plated on appropriate ______.

<p>media</p> Signup and view all the answers

Serodiagnosis is commonly used for diagnosing ______ pneumoniae infections.

<p>Mycoplasma</p> Signup and view all the answers

Disease expression varies somewhat with ______, partly because the diameters of the airways enlarge with maturation.

<p>age</p> Signup and view all the answers

An adult with a viral infection of the larynx (laryngitis) has a relatively better immune response than a ______ with the same infection.

<p>child</p> Signup and view all the answers

An infant or child with the same infection in the same site can develop a much more severe illness known as ______.

<p>croup</p> Signup and view all the answers

Bronchitis or tracheobronchitis is characterized by cough, variable fever, and ______ production.

<p>sputum</p> Signup and view all the answers

Chronic bronchitis is a result of longstanding damage to the bronchial ______.

<p>epithelium</p> Signup and view all the answers

A common cause of chronic bronchitis is ______ smoking.

<p>cigarette</p> Signup and view all the answers

With the exception of epiglottitis, acute diseases of the middle airway are usually caused by ______ agents.

<p>viral</p> Signup and view all the answers

Most subglottic middle airway infections are ______.

<p>viral</p> Signup and view all the answers

The quality of a sputum sample can be enhanced by collection early in the ______.

<p>morning</p> Signup and view all the answers

Contamination with oropharyngeal secretions is a primary ______ in sputum collection.

<p>problem</p> Signup and view all the answers

Microscopic examination before culture of direct Gram smears of specimens alleged to be sputum has proved ______.

<p>useful</p> Signup and view all the answers

Polymorphonuclear ______ and large numbers of a single morphologic type of organism are typical findings in sputum from patients with bacterial pneumonia.

<p>leukocytes</p> Signup and view all the answers

Squamous epithelial cells from the oropharynx and a mixed bacterial population are characteristic of ______.

<p>saliva</p> Signup and view all the answers

More than 10 to 25 squamous epithelial cells per low-power microscopic field are evidence of excessive ______ contamination.

<p>salivary</p> Signup and view all the answers

The direct Gram smear is crucial to the use of ______ sputum for diagnosis of acute bacterial pneumonia.

<p>expectorated</p> Signup and view all the answers

Salivary specimens should not be ______.

<p>cultured</p> Signup and view all the answers

Study Notes

Respiratory Tract Infections

  • Worldwide, 3-5 million children die annually from acute respiratory disease, a significant global health concern.
  • Respiratory infections are a common human health issue.
  • Upper respiratory infections (URIs) often involve nasal cavity and pharynx.
  • Over 80% of URIs are caused by viruses.
  • URI types are named for the affected area (e.g., rhinitis for nasal inflammation, pharyngitis for throat infection).
  • Infections can affect multiple areas simultaneously (e.g., rhinopharyngitis).
  • Rhinitis, the common cold, features variable fever, nasal inflammation, and increased mucous secretions.
  • Nasal discharge may initially be clear and watery but can thicken and become purulent over several days.
  • Pharyngitis and tonsillitis cause throat pain (sore throat) and inflammation/swelling of the throat tissues.
  • Pseudomembranes (necrotic tissue, inflammatory cells, and bacteria) are sometimes seen in severe cases, typically in pharyngeal diphtheria but can also be seen in fusospirochetal infection (Vincent's angina) and infectious mononucleosis.
  • Inflammation and swelling of the anterior cervical lymph nodes are also common in acute tonsillitis/pharyngitis.
  • Viral infections are more common than bacterial infections.
  • Vesicles and ulcerated lesions are often more common with a viral cause.
  • Pharyngeal lesions are more common in immunocompromised individuals.
  • URI can be a portal of entry for systemic infections.

Middle Respiratory Tract Infection

  • The middle respiratory tract consists of the epiglottis, larynx, trachea, and bronchi.
  • Infections may be localized (e.g., laryngitis) or more widespread (e.g., laryngotracheobronchitis).
  • Children are more likely to experience severe infections.
  • Symptoms vary with age, as airway diameters increase over time, which can reduce the severity of infections in adults.
  • Bronchitis/tracheobronchitis can be a primary infection or spread from upper respiratory infections.
  • Symptoms include cough, fever, and sputum production (initially clear then sometimes purulent).
  • Chronic bronchitis is a long-term bronchial injury often caused by cigarette smoking, environmental pollutants, and other diseases.
  • Viral agents are the most common cause of middle airway infections, excluding epiglottitis.

Lower Respiratory Tract Infection

  • Lower respiratory tract infections involve the lungs, including alveolar spaces, interstitium, and terminal bronchioles.
  • Infection can arise from extension of a middle respiratory tract infection, aspiration, or hematogenous spread.
  • Acute pneumonia involves lung parenchyma, progressing gradually or suddenly with cough, fever, and sputum production.
  • Sputum may be purulent, blood-streaked, or rust-colored.
  • Chronic pneumonia is characterized by a slow onset over weeks or months, similar symptoms to acute pneumonia, but with a more sustained course of illness.
  • Abscesses, cavities, and pleural effusions may develop.

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Description

This quiz explores the critical aspects of respiratory tract infections, focusing on their causes, symptoms, and impact on children's health. Learn about upper respiratory infections, their viral origins, and specific conditions like rhinitis and pharyngitis. Test your knowledge on how these infections affect various areas of the respiratory system.

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