Podcast
Questions and Answers
What is the typical duration of symptoms in acute rhinosinusitis?
What is the typical duration of symptoms in acute rhinosinusitis?
- More than 12 weeks
- Less than 4 weeks (correct)
- Between 4 and 12 weeks
- More than 6 months
What percentage of adults in the US are affected by sinusitis annually?
What percentage of adults in the US are affected by sinusitis annually?
- 1 in 20
- 1 in 50
- 1 in 7 (correct)
- 1 in 3
Purulent nasal discharge is classified as what type of symptom relating to rhinosinusitis?
Purulent nasal discharge is classified as what type of symptom relating to rhinosinusitis?
- A rare symptom
- A major symptom (correct)
- An irrelevant symptom
- A minor symptom
Which of the following is a common viral cause of rhinosinusitis?
Which of the following is a common viral cause of rhinosinusitis?
For adults, what is the typical treatment duration for bacterial rhinosinusitis with amoxicillin-clavulanate?
For adults, what is the typical treatment duration for bacterial rhinosinusitis with amoxicillin-clavulanate?
What adjunctive therapy is recommended for rhinosinusitis?
What adjunctive therapy is recommended for rhinosinusitis?
A patient's symptoms worsen after 48-72 hours of treatment, what should be considered?
A patient's symptoms worsen after 48-72 hours of treatment, what should be considered?
What is the primary cause of pharyngitis?
What is the primary cause of pharyngitis?
In adults, approximately what fraction of sore throats are caused by Group A Streptococcus (GAS)?
In adults, approximately what fraction of sore throats are caused by Group A Streptococcus (GAS)?
What causes Group A strep pharyngitis?
What causes Group A strep pharyngitis?
Which symptom is specifically associated with viral pharyngitis?
Which symptom is specifically associated with viral pharyngitis?
What is a common clinical finding in GAS pharyngitis?
What is a common clinical finding in GAS pharyngitis?
What is the recommended course of action following a negative rapid antigen detection test (RADT) for pharyngitis when viral features are absent?
What is the recommended course of action following a negative rapid antigen detection test (RADT) for pharyngitis when viral features are absent?
How is GAS pharyngitis typically transmitted?
How is GAS pharyngitis typically transmitted?
What is the recommended duration of treatment for GAS pharyngitis with oral penicillin?
What is the recommended duration of treatment for GAS pharyngitis with oral penicillin?
What medication is appropriate to avoid as adjunctive therapy in children with pharyngitis?
What medication is appropriate to avoid as adjunctive therapy in children with pharyngitis?
Which of the following is a potential delayed sequela of GAS infections?
Which of the following is a potential delayed sequela of GAS infections?
What is the most common age for rheumatic fever?
What is the most common age for rheumatic fever?
What is the primary goal of therapy in treating GAS pharyngitis?
What is the primary goal of therapy in treating GAS pharyngitis?
According to clinical practice guidelines, what should be done in management of Group A Streptococcal Pharyngitis?
According to clinical practice guidelines, what should be done in management of Group A Streptococcal Pharyngitis?
What is acute bronchitis characterized by?
What is acute bronchitis characterized by?
What is the duration of cough for acute bronchitis?
What is the duration of cough for acute bronchitis?
What is the most common cause of acute bronchitis?
What is the most common cause of acute bronchitis?
What is one of the symptoms of acute bronchitis
What is one of the symptoms of acute bronchitis
Which of the following symptoms are suggestive of pneumonia rather than bronchitis?
Which of the following symptoms are suggestive of pneumonia rather than bronchitis?
What kind of care would you recommend for acute bronchitis?
What kind of care would you recommend for acute bronchitis?
What is one of the components of symptomatic management for acute bronchitis?
What is one of the components of symptomatic management for acute bronchitis?
What should you recommend against to a patient with acute bronchitis
What should you recommend against to a patient with acute bronchitis
Which of the following is a risk associated with the overprescribing of antibiotics?
Which of the following is a risk associated with the overprescribing of antibiotics?
What strategies may reduce the reduced antibiotic use?
What strategies may reduce the reduced antibiotic use?
What is something you can say to your patients to help prevent them from thinking they need antibiotics to treat a viral infection or chest cold?
What is something you can say to your patients to help prevent them from thinking they need antibiotics to treat a viral infection or chest cold?
What is the initial step in differentiating between bacterial and viral etiologies of upper respiratory tract infections (URTIs)?
What is the initial step in differentiating between bacterial and viral etiologies of upper respiratory tract infections (URTIs)?
Which clinical manifestation is more indicative of bacterial sinusitis rather than viral sinusitis?
Which clinical manifestation is more indicative of bacterial sinusitis rather than viral sinusitis?
What is the primary strategy to reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs)?
What is the primary strategy to reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs)?
What is a key concept to consider when treating rhinosinusitis?
What is a key concept to consider when treating rhinosinusitis?
What is the typical treatment duration for bacterial pharyngitis with penicillin in children?
What is the typical treatment duration for bacterial pharyngitis with penicillin in children?
What is one of the components of symptomatic management for acute pharyngitis?
What is one of the components of symptomatic management for acute pharyngitis?
What is the primary characteristic of acute rhinosinusitis?
What is the primary characteristic of acute rhinosinusitis?
The presence of what classifies acute bacterial rhinosinusitis as severe?
The presence of what classifies acute bacterial rhinosinusitis as severe?
Which of the following is a common bacterial cause of acute bacterial rhinosinusitis?
Which of the following is a common bacterial cause of acute bacterial rhinosinusitis?
What is a key treatment consideration in managing acute bacterial rhinosinusitis?
What is a key treatment consideration in managing acute bacterial rhinosinusitis?
When should a switch to an alternate antibiotic be considered in treating rhinosinusitis?
When should a switch to an alternate antibiotic be considered in treating rhinosinusitis?
What is the primary cause of most cases of pharyngitis?
What is the primary cause of most cases of pharyngitis?
What is the most common bacterial cause of acute pharyngitis?
What is the most common bacterial cause of acute pharyngitis?
How is Group A Streptococcus (GAS) pharyngitis typically spread?
How is Group A Streptococcus (GAS) pharyngitis typically spread?
What is an appropriate adjunctive therapy recommendation for viral pharyngitis?
What is an appropriate adjunctive therapy recommendation for viral pharyngitis?
What is a potential delayed complication of Group A Streptococcus (GAS) infections?
What is a potential delayed complication of Group A Streptococcus (GAS) infections?
What is the primary characteristic of acute bronchitis?
What is the primary characteristic of acute bronchitis?
Which of the following is a typical symptom of acute bronchitis?
Which of the following is a typical symptom of acute bronchitis?
What is generally recommended in the treatment of acute bronchitis?
What is generally recommended in the treatment of acute bronchitis?
What is a recommended strategy to reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs)?
What is a recommended strategy to reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs)?
Inflammation of the mucosal lining affecting the nasal passage and paranasal sinuses, with symptoms lasting less than 4 weeks, is best described as:
Inflammation of the mucosal lining affecting the nasal passage and paranasal sinuses, with symptoms lasting less than 4 weeks, is best described as:
Approximately what proportion of adults in the United States are affected by sinusitis each year?
Approximately what proportion of adults in the United States are affected by sinusitis each year?
A patient presents with nasal congestion, facial pain, and purulent nasal discharge. Which of these is classified as a MAJOR symptom in the clinical presentation of acute rhinosinusitis?
A patient presents with nasal congestion, facial pain, and purulent nasal discharge. Which of these is classified as a MAJOR symptom in the clinical presentation of acute rhinosinusitis?
Which diagnostic approach is generally considered LEAST necessary for diagnosing uncomplicated acute bacterial rhinosinusitis?
Which diagnostic approach is generally considered LEAST necessary for diagnosing uncomplicated acute bacterial rhinosinusitis?
The majority of acute rhinosinusitis cases are attributed to which type of pathogen?
The majority of acute rhinosinusitis cases are attributed to which type of pathogen?
A patient with rhinosinusitis presents with symptoms for 8 days that are not worsening. Which of the following best indicates a VIRAL etiology rather than bacterial?
A patient with rhinosinusitis presents with symptoms for 8 days that are not worsening. Which of the following best indicates a VIRAL etiology rather than bacterial?
Which of the following bacterial pathogens is a primary cause of acute bacterial sinusitis?
Which of the following bacterial pathogens is a primary cause of acute bacterial sinusitis?
Which key concept is MOST important to consider when treating acute bacterial rhinosinusitis (ABRS) in the outpatient setting?
Which key concept is MOST important to consider when treating acute bacterial rhinosinusitis (ABRS) in the outpatient setting?
For an adult patient diagnosed with acute bacterial rhinosinusitis, what is a typical first-line antibiotic treatment regimen?
For an adult patient diagnosed with acute bacterial rhinosinusitis, what is a typical first-line antibiotic treatment regimen?
In pediatric patients with acute bacterial rhinosinusitis, a high dose of amoxicillin-clavulanate (45 mg/kg/day) is particularly recommended in which scenario?
In pediatric patients with acute bacterial rhinosinusitis, a high dose of amoxicillin-clavulanate (45 mg/kg/day) is particularly recommended in which scenario?
What is the recommended duration of antibiotic treatment for acute bacterial rhinosinusitis in adults?
What is the recommended duration of antibiotic treatment for acute bacterial rhinosinusitis in adults?
Intranasal saline irrigation is recommended as what type of therapy in managing acute rhinosinusitis?
Intranasal saline irrigation is recommended as what type of therapy in managing acute rhinosinusitis?
In a patient with acute bacterial rhinosinusitis who is nonresponsive to initial antibiotic therapy, when is it recommended to consider switching to an alternate antibiotic?
In a patient with acute bacterial rhinosinusitis who is nonresponsive to initial antibiotic therapy, when is it recommended to consider switching to an alternate antibiotic?
Infectious Diseases Society of America (IDSA) guidelines recommend considering which antibiotic for acute bacterial rhinosinusitis?
Infectious Diseases Society of America (IDSA) guidelines recommend considering which antibiotic for acute bacterial rhinosinusitis?
Pharyngitis is MOST commonly caused by which type of pathogen?
Pharyngitis is MOST commonly caused by which type of pathogen?
What is the estimated number of pediatrician/primary care visits annually in the US due to pharyngitis?
What is the estimated number of pediatrician/primary care visits annually in the US due to pharyngitis?
Group A Streptococcus (GAS) is the MOST common cause of what type of acute pharyngitis?
Group A Streptococcus (GAS) is the MOST common cause of what type of acute pharyngitis?
In children, approximately what proportion of sore throats are caused by Group A Streptococcus (GAS)?
In children, approximately what proportion of sore throats are caused by Group A Streptococcus (GAS)?
Which of the following clinical findings is MORE suggestive of viral pharyngitis compared to Group A Strep pharyngitis?
Which of the following clinical findings is MORE suggestive of viral pharyngitis compared to Group A Strep pharyngitis?
When is testing for Group A Streptococcus (GAS) pharyngitis generally NOT recommended?
When is testing for Group A Streptococcus (GAS) pharyngitis generally NOT recommended?
What is the typical mode of transmission for Group A Streptococcus (GAS) pharyngitis?
What is the typical mode of transmission for Group A Streptococcus (GAS) pharyngitis?
What is the recommended duration of treatment for Group A Streptococcus (GAS) pharyngitis with oral penicillin?
What is the recommended duration of treatment for Group A Streptococcus (GAS) pharyngitis with oral penicillin?
In children with pharyngitis, which adjunctive therapy should be avoided?
In children with pharyngitis, which adjunctive therapy should be avoided?
Rheumatic fever is a potential delayed sequela of infection caused by which pathogen?
Rheumatic fever is a potential delayed sequela of infection caused by which pathogen?
What is the primary goal of antibiotic therapy in treating Group A Streptococcus (GAS) pharyngitis?
What is the primary goal of antibiotic therapy in treating Group A Streptococcus (GAS) pharyngitis?
According to clinical practice guidelines from IDSA, what is the recommended approach for managing Group A Streptococcal Pharyngitis?
According to clinical practice guidelines from IDSA, what is the recommended approach for managing Group A Streptococcal Pharyngitis?
Acute bronchitis is primarily characterized by inflammation of:
Acute bronchitis is primarily characterized by inflammation of:
What is the typical duration of cough associated with acute bronchitis?
What is the typical duration of cough associated with acute bronchitis?
What is the MOST common etiology of acute bronchitis?
What is the MOST common etiology of acute bronchitis?
Which of the following symptoms is commonly associated with acute bronchitis?
Which of the following symptoms is commonly associated with acute bronchitis?
Which clinical finding is MORE suggestive of pneumonia rather than acute bronchitis?
Which clinical finding is MORE suggestive of pneumonia rather than acute bronchitis?
The primary approach to managing acute bronchitis in otherwise healthy adults is:
The primary approach to managing acute bronchitis in otherwise healthy adults is:
Which of the following is a recommended component of symptomatic management for acute bronchitis?
Which of the following is a recommended component of symptomatic management for acute bronchitis?
In the management of acute bronchitis, what should be generally discouraged?
In the management of acute bronchitis, what should be generally discouraged?
What is a significant risk associated with the overprescribing of antibiotics for upper respiratory infections?
What is a significant risk associated with the overprescribing of antibiotics for upper respiratory infections?
Which of the following is a strategy to reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs)?
Which of the following is a strategy to reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs)?
What is a key message to communicate to patients to prevent them from expecting antibiotics for viral infections like a chest cold?
What is a key message to communicate to patients to prevent them from expecting antibiotics for viral infections like a chest cold?
What is the primary strategy for reducing inappropriate antibiotic use in the context of upper respiratory tract infections (URTIs)?
What is the primary strategy for reducing inappropriate antibiotic use in the context of upper respiratory tract infections (URTIs)?
Which of the following is a component of symptomatic management for acute pharyngitis, regardless of etiology?
Which of the following is a component of symptomatic management for acute pharyngitis, regardless of etiology?
What is the primary characteristic defining acute rhinosinusitis?
What is the primary characteristic defining acute rhinosinusitis?
The presence of which symptom, in acute bacterial rhinosinusitis, classifies it as 'severe'?
The presence of which symptom, in acute bacterial rhinosinusitis, classifies it as 'severe'?
Which of the following is a common bacterial cause of acute bacterial rhinosinusitis (ABRS)?
Which of the following is a common bacterial cause of acute bacterial rhinosinusitis (ABRS)?
A 35-year-old patient presents with nasal congestion, facial pain, and purulent nasal discharge for 6 days which started after a week of clear nasal discharge and mild cough. Which of the following best differentiates a bacterial etiology from a viral etiology in this case of acute rhinosinusitis?
A 35-year-old patient presents with nasal congestion, facial pain, and purulent nasal discharge for 6 days which started after a week of clear nasal discharge and mild cough. Which of the following best differentiates a bacterial etiology from a viral etiology in this case of acute rhinosinusitis?
Which of the following bacterial pathogens is the MOST common cause of acute bacterial rhinosinusitis (ABRS)?
Which of the following bacterial pathogens is the MOST common cause of acute bacterial rhinosinusitis (ABRS)?
What is the generally recommended duration of antibiotic therapy for an adult diagnosed with uncomplicated acute bacterial rhinosinusitis?
What is the generally recommended duration of antibiotic therapy for an adult diagnosed with uncomplicated acute bacterial rhinosinusitis?
In a pediatric patient with acute bacterial rhinosinusitis, when is high-dose amoxicillin-clavulanate (45 mg/kg/day) particularly recommended as the first-line treatment?
In a pediatric patient with acute bacterial rhinosinusitis, when is high-dose amoxicillin-clavulanate (45 mg/kg/day) particularly recommended as the first-line treatment?
A 6-year-old child is diagnosed with acute bacterial rhinosinusitis. What is the typical duration of antibiotic treatment recommended for pediatric patients?
A 6-year-old child is diagnosed with acute bacterial rhinosinusitis. What is the typical duration of antibiotic treatment recommended for pediatric patients?
Which of the following is an appropriate adjunctive therapy to recommend to a patient with acute rhinosinusitis to help relieve symptoms?
Which of the following is an appropriate adjunctive therapy to recommend to a patient with acute rhinosinusitis to help relieve symptoms?
A patient with acute bacterial rhinosinusitis has been treated with amoxicillin-clavulanate for 3 days and reports no improvement in symptoms, but also no worsening. When should a switch to an alternate antibiotic be considered?
A patient with acute bacterial rhinosinusitis has been treated with amoxicillin-clavulanate for 3 days and reports no improvement in symptoms, but also no worsening. When should a switch to an alternate antibiotic be considered?
What is the MOST common etiology of pharyngitis?
What is the MOST common etiology of pharyngitis?
Which clinical finding is MORE suggestive of Group A Streptococcal (GAS) pharyngitis compared to viral pharyngitis?
Which clinical finding is MORE suggestive of Group A Streptococcal (GAS) pharyngitis compared to viral pharyngitis?
What is the recommended duration of treatment with oral penicillin for Group A Streptococcus (GAS) pharyngitis to prevent the development of rheumatic fever?
What is the recommended duration of treatment with oral penicillin for Group A Streptococcus (GAS) pharyngitis to prevent the development of rheumatic fever?
In managing a 7-year-old child with pharyngitis, which of the following adjunctive therapies should be avoided due to potential risks?
In managing a 7-year-old child with pharyngitis, which of the following adjunctive therapies should be avoided due to potential risks?
Rheumatic fever is a potential delayed sequela of infection caused by which specific pathogen?
Rheumatic fever is a potential delayed sequela of infection caused by which specific pathogen?
To reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs), what is a key communication strategy for healthcare providers when speaking with patients?
To reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs), what is a key communication strategy for healthcare providers when speaking with patients?
A 45-year-old patient presents with symptoms suggestive of acute rhinosinusitis. Which of the following clinical findings would most strongly suggest a bacterial rather than a viral etiology?
A 45-year-old patient presents with symptoms suggestive of acute rhinosinusitis. Which of the following clinical findings would most strongly suggest a bacterial rather than a viral etiology?
In the outpatient management of acute bacterial rhinosinusitis (ABRS) in adults, which factor would most strongly support the recommendation for high-dose amoxicillin-clavulanate (2000/125 mg BID) over standard-dose amoxicillin-clavulanate (875/125 mg BID)?
In the outpatient management of acute bacterial rhinosinusitis (ABRS) in adults, which factor would most strongly support the recommendation for high-dose amoxicillin-clavulanate (2000/125 mg BID) over standard-dose amoxicillin-clavulanate (875/125 mg BID)?
A 5-year-old child is diagnosed with acute bacterial rhinosinusitis and prescribed amoxicillin-clavulanate. After 72 hours, the child's parent reports no significant improvement in symptoms, but also no worsening. What is the most appropriate next step in managing this patient?
A 5-year-old child is diagnosed with acute bacterial rhinosinusitis and prescribed amoxicillin-clavulanate. After 72 hours, the child's parent reports no significant improvement in symptoms, but also no worsening. What is the most appropriate next step in managing this patient?
Which of the following adjunctive therapies for acute rhinosinusitis has the strongest evidence supporting its recommendation in clinical guidelines?
Which of the following adjunctive therapies for acute rhinosinusitis has the strongest evidence supporting its recommendation in clinical guidelines?
A patient with acute bacterial rhinosinusitis (ABRS) is being treated with amoxicillin-clavulanate. Which scenario would warrant considering a switch to an alternative antibiotic due to treatment failure?
A patient with acute bacterial rhinosinusitis (ABRS) is being treated with amoxicillin-clavulanate. Which scenario would warrant considering a switch to an alternative antibiotic due to treatment failure?
In differentiating between viral and Group A Streptococcal (GAS) pharyngitis, which clinical finding is most suggestive of GAS pharyngitis?
In differentiating between viral and Group A Streptococcal (GAS) pharyngitis, which clinical finding is most suggestive of GAS pharyngitis?
A 6-year-old child presents with acute pharyngitis. A rapid antigen detection test (RADT) for Group A Streptococcus (GAS) is negative. Viral features such as cough and rhinorrhea are absent. What is the most appropriate next step in management?
A 6-year-old child presents with acute pharyngitis. A rapid antigen detection test (RADT) for Group A Streptococcus (GAS) is negative. Viral features such as cough and rhinorrhea are absent. What is the most appropriate next step in management?
Which of the following best describes the primary goal of antibiotic therapy in the treatment of Group A Streptococcal (GAS) pharyngitis?
Which of the following best describes the primary goal of antibiotic therapy in the treatment of Group A Streptococcal (GAS) pharyngitis?
For a child with a confirmed Group A Streptococcus (GAS) pharyngitis and no penicillin allergy, which of the following is the recommended duration of treatment with oral penicillin to prevent rheumatic fever?
For a child with a confirmed Group A Streptococcus (GAS) pharyngitis and no penicillin allergy, which of the following is the recommended duration of treatment with oral penicillin to prevent rheumatic fever?
In managing a 4-year-old child with viral pharyngitis, which of the following adjunctive therapies should be avoided due to lack of benefit and potential risks in this age group?
In managing a 4-year-old child with viral pharyngitis, which of the following adjunctive therapies should be avoided due to lack of benefit and potential risks in this age group?
Which of the following is the most accurate description of acute bronchitis?
Which of the following is the most accurate description of acute bronchitis?
A patient presents with a cough for 10 days, associated with clear sputum, mild chest discomfort, and wheezing. Which of the following clinical findings would be most suggestive of pneumonia rather than acute bronchitis?
A patient presents with a cough for 10 days, associated with clear sputum, mild chest discomfort, and wheezing. Which of the following clinical findings would be most suggestive of pneumonia rather than acute bronchitis?
What is the primary approach to managing acute bronchitis in an otherwise healthy adult patient?
What is the primary approach to managing acute bronchitis in an otherwise healthy adult patient?
In the context of acute bronchitis management, what is the most significant risk associated with the overprescription of antibiotics?
In the context of acute bronchitis management, what is the most significant risk associated with the overprescription of antibiotics?
Which strategy is most effective in reducing inappropriate antibiotic use for upper respiratory tract infections (URTIs) in outpatient settings?
Which strategy is most effective in reducing inappropriate antibiotic use for upper respiratory tract infections (URTIs) in outpatient settings?
When communicating with patients about upper respiratory tract infections (URTIs), which message is most crucial to convey to reduce patient expectations for antibiotics?
When communicating with patients about upper respiratory tract infections (URTIs), which message is most crucial to convey to reduce patient expectations for antibiotics?
In the context of antibiotic stewardship for upper respiratory infections, what is the initial, most important step in clinical decision-making?
In the context of antibiotic stewardship for upper respiratory infections, what is the initial, most important step in clinical decision-making?
For acute bacterial rhinosinusitis (ABRS), which key concept most significantly influences outpatient treatment decisions?
For acute bacterial rhinosinusitis (ABRS), which key concept most significantly influences outpatient treatment decisions?
Which of the following scenarios represents a situation where testing for Group A Streptococcus (GAS) pharyngitis would generally NOT be recommended?
Which of the following scenarios represents a situation where testing for Group A Streptococcus (GAS) pharyngitis would generally NOT be recommended?
What is the typical duration of cough associated with acute bronchitis, which should be communicated to patients to manage expectations?
What is the typical duration of cough associated with acute bronchitis, which should be communicated to patients to manage expectations?
A patient with acute bronchitis is considering using over-the-counter (OTC) medications for symptom relief. Which of the following OTC medication classes should generally be avoided or used with caution, particularly in young children, due to minimal benefit and potential risks?
A patient with acute bronchitis is considering using over-the-counter (OTC) medications for symptom relief. Which of the following OTC medication classes should generally be avoided or used with caution, particularly in young children, due to minimal benefit and potential risks?
Which of the following best describes 'worsening' acute bacterial rhinosinusitis (ABRS) as a differentiator from viral rhinosinusitis?
Which of the following best describes 'worsening' acute bacterial rhinosinusitis (ABRS) as a differentiator from viral rhinosinusitis?
In pediatric acute bacterial rhinosinusitis (ABRS), when is the use of high-dose amoxicillin-clavulanate (45 mg/kg/day) particularly recommended as first-line therapy?
In pediatric acute bacterial rhinosinusitis (ABRS), when is the use of high-dose amoxicillin-clavulanate (45 mg/kg/day) particularly recommended as first-line therapy?
What is the most common viral etiology of acute bronchitis?
What is the most common viral etiology of acute bronchitis?
Which of the following is a potential delayed non-suppurative sequela specifically associated with Group A Streptococcus (GAS) infections, such as pharyngitis?
Which of the following is a potential delayed non-suppurative sequela specifically associated with Group A Streptococcus (GAS) infections, such as pharyngitis?
In managing Group A Streptococcal (GAS) pharyngitis, clinical practice guidelines from the Infectious Diseases Society of America (IDSA) recommend which approach?
In managing Group A Streptococcal (GAS) pharyngitis, clinical practice guidelines from the Infectious Diseases Society of America (IDSA) recommend which approach?
Which of the following best exemplifies a 'delayed prescription' strategy for managing upper respiratory tract infections (URTIs) to reduce antibiotic use?
Which of the following best exemplifies a 'delayed prescription' strategy for managing upper respiratory tract infections (URTIs) to reduce antibiotic use?
What is the estimated proportion of adult sore throats that are caused by Group A Streptococcus (GAS)?
What is the estimated proportion of adult sore throats that are caused by Group A Streptococcus (GAS)?
Which of the following symptoms is LEAST likely to be associated with acute bronchitis and would warrant consideration of an alternative diagnosis such as pneumonia?
Which of the following symptoms is LEAST likely to be associated with acute bronchitis and would warrant consideration of an alternative diagnosis such as pneumonia?
In the context of acute rhinosinusitis, what does the term 'severe' acute bacterial rhinosinusitis (ABRS) primarily indicate?
In the context of acute rhinosinusitis, what does the term 'severe' acute bacterial rhinosinusitis (ABRS) primarily indicate?
Which of the following is considered a 'major' symptom in the clinical presentation of acute rhinosinusitis according to clinical guidelines?
Which of the following is considered a 'major' symptom in the clinical presentation of acute rhinosinusitis according to clinical guidelines?
Which of the following diagnostic approaches is generally considered LEAST necessary for diagnosing uncomplicated acute bacterial rhinosinusitis (ABRS) in an outpatient setting?
Which of the following diagnostic approaches is generally considered LEAST necessary for diagnosing uncomplicated acute bacterial rhinosinusitis (ABRS) in an outpatient setting?
What is the typical treatment duration for acute bacterial rhinosinusitis (ABRS) with antibiotics in adults, according to clinical guidelines?
What is the typical treatment duration for acute bacterial rhinosinusitis (ABRS) with antibiotics in adults, according to clinical guidelines?
Which of the following antibiotics is recommended by the Infectious Diseases Society of America (IDSA) guidelines as a first-line treatment option for acute bacterial rhinosinusitis (ABRS) in adults?
Which of the following antibiotics is recommended by the Infectious Diseases Society of America (IDSA) guidelines as a first-line treatment option for acute bacterial rhinosinusitis (ABRS) in adults?
In the treatment of acute pharyngitis, when is a follow-up throat culture most strongly recommended after a negative rapid antigen detection test (RADT) for Group A Streptococcus (GAS)?
In the treatment of acute pharyngitis, when is a follow-up throat culture most strongly recommended after a negative rapid antigen detection test (RADT) for Group A Streptococcus (GAS)?
What is the most common age group for the occurrence of rheumatic fever as a sequela of Group A Streptococcus (GAS) infection?
What is the most common age group for the occurrence of rheumatic fever as a sequela of Group A Streptococcus (GAS) infection?
According to the clinical practice guidelines, what is the recommended management of Group A Streptococcal Pharyngitis?
According to the clinical practice guidelines, what is the recommended management of Group A Streptococcal Pharyngitis?
A 40-year-old patient presents with acute rhinosinusitis symptoms for 12 days, including persistent nasal congestion and purulent discharge. The symptoms have remained consistent without significant improvement or worsening since onset. Which of the following clinical features, if present, would most strongly suggest a bacterial etiology over a viral etiology in this patient's rhinosinusitis?
A 40-year-old patient presents with acute rhinosinusitis symptoms for 12 days, including persistent nasal congestion and purulent discharge. The symptoms have remained consistent without significant improvement or worsening since onset. Which of the following clinical features, if present, would most strongly suggest a bacterial etiology over a viral etiology in this patient's rhinosinusitis?
In the outpatient management of acute bacterial rhinosinusitis (ABRS) for an adult patient with no known penicillin allergy and no significant comorbidities, which of the following factors would most compellingly advocate for the use of high-dose amoxicillin-clavulanate (2000/125 mg BID) over standard-dose amoxicillin-clavulanate (875/125 mg BID) as first-line therapy?
In the outpatient management of acute bacterial rhinosinusitis (ABRS) for an adult patient with no known penicillin allergy and no significant comorbidities, which of the following factors would most compellingly advocate for the use of high-dose amoxicillin-clavulanate (2000/125 mg BID) over standard-dose amoxicillin-clavulanate (875/125 mg BID) as first-line therapy?
A 7-year-old child is diagnosed with acute bacterial rhinosinusitis and initiated on amoxicillin-clavulanate. After 72 hours of treatment, the parent reports that the child's symptoms, including nasal discharge and facial pain, have shown minimal improvement but have not worsened. Which of the following is the most clinically appropriate next step in managing this patient?
A 7-year-old child is diagnosed with acute bacterial rhinosinusitis and initiated on amoxicillin-clavulanate. After 72 hours of treatment, the parent reports that the child's symptoms, including nasal discharge and facial pain, have shown minimal improvement but have not worsened. Which of the following is the most clinically appropriate next step in managing this patient?
Which of the following adjunctive therapies for acute rhinosinusitis has the most robust evidence base supporting its recommendation for symptomatic relief in clinical practice guidelines?
Which of the following adjunctive therapies for acute rhinosinusitis has the most robust evidence base supporting its recommendation for symptomatic relief in clinical practice guidelines?
A 50-year-old patient with acute bacterial rhinosinusitis (ABRS) is being treated with amoxicillin-clavulanate. After 5 days of therapy, the patient reports persistent severe headache, worsening facial pain, and new onset of periorbital edema. Which of the following clinical scenarios would most strongly warrant considering a switch to an alternative antibiotic and further diagnostic evaluation?
A 50-year-old patient with acute bacterial rhinosinusitis (ABRS) is being treated with amoxicillin-clavulanate. After 5 days of therapy, the patient reports persistent severe headache, worsening facial pain, and new onset of periorbital edema. Which of the following clinical scenarios would most strongly warrant considering a switch to an alternative antibiotic and further diagnostic evaluation?
In differentiating between viral and Group A Streptococcal (GAS) pharyngitis in a 10-year-old child presenting with acute sore throat, which of the following clinical findings is most suggestive of GAS pharyngitis rather than a viral etiology?
In differentiating between viral and Group A Streptococcal (GAS) pharyngitis in a 10-year-old child presenting with acute sore throat, which of the following clinical findings is most suggestive of GAS pharyngitis rather than a viral etiology?
A 5-year-old child presents with acute pharyngitis. A rapid antigen detection test (RADT) for Group A Streptococcus (GAS) is performed in the clinic and is negative. Viral features such as cough, rhinorrhea, and conjunctivitis are notably absent during the clinical examination. What is the most appropriate next step in the management of this child?
A 5-year-old child presents with acute pharyngitis. A rapid antigen detection test (RADT) for Group A Streptococcus (GAS) is performed in the clinic and is negative. Viral features such as cough, rhinorrhea, and conjunctivitis are notably absent during the clinical examination. What is the most appropriate next step in the management of this child?
For a 9-year-old child with a confirmed Group A Streptococcus (GAS) pharyngitis and no penicillin allergy, which of the following is the guideline-recommended duration of treatment with oral penicillin to prevent rheumatic fever?
For a 9-year-old child with a confirmed Group A Streptococcus (GAS) pharyngitis and no penicillin allergy, which of the following is the guideline-recommended duration of treatment with oral penicillin to prevent rheumatic fever?
In managing a 4-year-old child with viral pharyngitis, which of the following adjunctive therapies should be avoided or used with caution due to lack of proven benefit and potential risks in this age group?
In managing a 4-year-old child with viral pharyngitis, which of the following adjunctive therapies should be avoided or used with caution due to lack of proven benefit and potential risks in this age group?
Which of the following best describes the pathophysiology of acute bronchitis?
Which of the following best describes the pathophysiology of acute bronchitis?
A 68-year-old patient presents with a cough for 12 days, productive of clear sputum, associated with mild chest discomfort and wheezing. Which of the following clinical findings, if present, would be most concerning and suggestive of pneumonia rather than uncomplicated acute bronchitis?
A 68-year-old patient presents with a cough for 12 days, productive of clear sputum, associated with mild chest discomfort and wheezing. Which of the following clinical findings, if present, would be most concerning and suggestive of pneumonia rather than uncomplicated acute bronchitis?
In the context of acute bronchitis management, what is the most significant and broadly applicable risk associated with the overprescription of antibiotics?
In the context of acute bronchitis management, what is the most significant and broadly applicable risk associated with the overprescription of antibiotics?
To effectively reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs) in outpatient settings, which of the following strategies is considered most impactful at the healthcare provider level?
To effectively reduce inappropriate antibiotic use for upper respiratory tract infections (URTIs) in outpatient settings, which of the following strategies is considered most impactful at the healthcare provider level?
When communicating with patients about upper respiratory tract infections (URTIs) like acute bronchitis or viral rhinosinusitis, which of the following key messages is most crucial to convey to manage patient expectations and reduce antibiotic demand?
When communicating with patients about upper respiratory tract infections (URTIs) like acute bronchitis or viral rhinosinusitis, which of the following key messages is most crucial to convey to manage patient expectations and reduce antibiotic demand?
Flashcards
Differentiate Etiologies of URTIs
Differentiate Etiologies of URTIs
Distinguishing between infections caused by bacteria versus viruses.
Describe URTIs (Sinusitis, Pharyngitis, Bronchitis)
Describe URTIs (Sinusitis, Pharyngitis, Bronchitis)
Understanding the microbial agents, spread, disease signs, diagnosis methods, and treatments for infections like sinus infections, sore throat, and acute bronchitis.
Discuss Overprescribing of Antibiotics for URTIs
Discuss Overprescribing of Antibiotics for URTIs
Explaining why antibiotics are often unnecessarily prescribed for upper respiratory infections, and finding ways to reduce this overuse.
Acute Rhinosinusitis
Acute Rhinosinusitis
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Sinusitis Presentation
Sinusitis Presentation
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Sinusitis Diagnosis
Sinusitis Diagnosis
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Bacterial vs. Viral Sinusitis
Bacterial vs. Viral Sinusitis
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Common Sinusitis Bacteria
Common Sinusitis Bacteria
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Sinusitis Treatment Concepts
Sinusitis Treatment Concepts
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First-line Sinusitis Treatment
First-line Sinusitis Treatment
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Pharyngitis
Pharyngitis
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Pharyngitis Etiology
Pharyngitis Etiology
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Strep Throat Cause
Strep Throat Cause
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Strep Throat Symptoms
Strep Throat Symptoms
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Pharyngitis Symptoms
Pharyngitis Symptoms
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Strep Throat Diagnosis
Strep Throat Diagnosis
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Strep Throat Treatment
Strep Throat Treatment
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Acute Bronchitis
Acute Bronchitis
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Bronchitis Etiology
Bronchitis Etiology
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Bronchitis Symptoms
Bronchitis Symptoms
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Bronchitis Treatment
Bronchitis Treatment
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Pneumonia Indicators
Pneumonia Indicators
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Reducing Antibiotic Use
Reducing Antibiotic Use
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Antibiotic Overuse Consequences
Antibiotic Overuse Consequences
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Differentiate Viral & Bacterial URTIs
Differentiate Viral & Bacterial URTIs
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Describe Microbiology, Epidemiology, Clinical Profile, Diagnosis, & Treatment
Describe Microbiology, Epidemiology, Clinical Profile, Diagnosis, & Treatment
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Discuss Antibiotic Overuse for URTIs
Discuss Antibiotic Overuse for URTIs
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Define Acute Rhinosinusitis
Define Acute Rhinosinusitis
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Recognizing Bacterial Sinusitis
Recognizing Bacterial Sinusitis
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Identify Common Bacterial Sinusitis Pathogens
Identify Common Bacterial Sinusitis Pathogens
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Outline Appropriate Acute Bacterial Rhinosinusitis Treatment
Outline Appropriate Acute Bacterial Rhinosinusitis Treatment
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Define pharyngitis
Define pharyngitis
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How To Test For GAS (group A streptococcus)
How To Test For GAS (group A streptococcus)
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Goals of therapy
Goals of therapy
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Outline Appropriate Acute Bronchitis Treatment
Outline Appropriate Acute Bronchitis Treatment
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List Strategies To Reduce Antibiotic Use
List Strategies To Reduce Antibiotic Use
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Study Notes
- Differentiate between bacterial and viral etiologies of Upper Respiratory Tract Infections (URTIs).
- Describe the microbiology, epidemiology, clinical manifestations, diagnosis, and treatment of sinusitis, pharyngitis, and acute bronchitis.
- Discuss the overprescribing of antibiotics for URTIs and strategies to reduce inappropriate use.
Acute Rhinosinusitis
- Acute rhinosinusitis involves inflammation of the mucosal lining in the nasal passage and paranasal sinuses.
- Acute rhinosinusitis lasts for less than 4 weeks.
- Sinusitis impacts 1 in 7 adults in the U.S. annually.
- Sinusitis is the 5th most common diagnosis responsible for antibiotic therapy.
- Major clinical presentations include purulent nasal discharge, nasal congestion or obstruction, facial congestion or fullness, and facial pain or pressure.
- Minor clinical presentations include hyposmia or anosmia, fever, headache, ear pain/pressure/fullness, halitosis, dental pain, cough, and fatigue.
- Diagnosis involves sinus aspiration and culture, imaging studies, compatible signs and symptoms, and differentiating bacterial vs. viral etiologies.
- Viral causes account for 90-98% of rhinosinusitis cases, including rhinoviruses, coronaviruses, influenza viruses, and adenoviruses.
- Bacterial causes account for 2-10% of rhinosinusitis cases.
- Presistent symptoms last greater than 10 days without improvement and can indicate bacterial infections.
- Severe symptoms, like high fever (≥ 39° C) and purulent nasal discharge or facial pain lasting ≥ 3-4 days can indicate bacterial infections.
- Worsening symptoms, including new onset fever, headache, and increased discharge following a typical viral URTI lasting 5-6 days, can indicate bacterial infections.
- Common bacterial causes of sinusitis are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
- Spontaneous recovery from sinusitis is common.
- There is often a lack of microbiologic information, antibiotics should be initiated once acute bacterial rhinosinusitis (ABRS) is established.
- Increasing antimicrobial resistance is a key concept in treatment.
- Amoxicillin-clavulanate is used for ABRS outpatient treatment.
- Adults: 500/125 mg orally three times daily or 875/125 mg orally twice daily.
- High dose: 2000/125 mg orally twice daily.
- Pediatrics: 45 mg/kg/day orally, divided twice daily.
- High dose: 45 mg/kg orally twice daily.
- A high dose of Amoxicillin-clavulanate is needed if there are high rates of penicillin non-susceptible S. pneumoniae (≥ 10%), severe infection (≥ 39° C), age < 2 or > 65 years, recent hospitalization, antibiotic use within the past month, daycare attendance, or the patient is immunocompromised.
- Alternative therapies for adults include doxycycline 100 mg orally twice daily, levofloxacin 500 mg orally daily, or moxifloxacin 400 mg orally daily.
- Alternative therapies for pediatrics include levofloxacin 10-20 mg/kg/day orally every 12-24 hours or clindamycin 30-40 mg/kg/day orally three times daily + cefixime 8 mg/kg/day orally twice daily OR cefpodoxime 10 mg/kg/day orally twice daily.
- Severe disease may require IV antibiotics.
- Treatment duration is 5-7 days for adults and 10-14 days for pediatrics.
- Intranasal saline irrigation and intranasal corticosteroids in allergic rhinitis are adjunctive therapies.
- Decongestants and antihistamines are not recommended.
- Switch to an alternate antibiotic for symptoms worsening after 48-72 hours, or failure to improve after 3-5 days of empiric antibiotics.
- Important considerations include resistant pathogens, noninfectious etiology, structural abnormality, and other causes for treatment failure.
- Culture is recommended for nonresponsive patients.
- Clinical Practice Guidelines include the Infectious Diseases Society of America (IDSA) - 2012, and American Academy of Otolaryngology – Head and Neck Surgery – 2015 (adult only).
- The American Academy of Otolaryngology recommends Amoxicillin with/without clavulanate for 5-10 days for adults only.
Pharyngitis
- Pharyngitis is an infection of the oropharynx.
- It is predominately caused by viral pathogens, including adenovirus, influenza, parainfluenza, rhinovirus, RSV, Epstein-Barr virus, coxsackievirus, and HSV.
- "Strep throat" is acute pharyngitis caused by Streptococcus pyogenes.
- There are 15 million pediatrician/primary care visits per year in the U.S. due to pharyngitis.
- It is most common in children ages 5-15.
- Group A strep pharyngitis is caused by Streptococcus pyogenes (Group A strep - GAS).
- GAS is the most common bacterial cause of acute pharyngitis.
- In children, 3/10 sore throats are GAS strep throat.
- In adults, 1/10 sore throats are GAS strep throat.
- Group A strep pharyngitis most commonly occurs in winter and early spring.
- Other GAS symptoms: headache, abdominal pain, and nausea/vomiting.
- Viral symptoms include cough, rhinorrhea, hoarseness, oral ulcers, and conjunctivitis.
- Clinical findings include tonsillopharyngeal erythema +/- exudates, tender or enlarged lymph nodes, a red swollen uvula, petechiae on the palate, and a scarlatiniform rash.
- Diagnosis inolves a throat swab and rapid antigen detection testing (RADT) and/or culture.
- Testing is not recommended if viral features are present or in children < 3 years old.
- Transmission of pharyngitis occurs through respiratory droplets and direct contact.
- The incubation period is 2-5 days.
- Treatment options for GAS only:
- Penicillin V: Children: 250 mg orally 2-3x/day; Adults: 250 mg orally 4x/day or 500 mg orally twice daily for 10 days.
- Amoxicillin: 25 mg/kg (max 500 mg) orally twice daily or 50 mg/kg/day (max 1000 mg) orally for 10 days.
- Benzathine penicillin G: < 27 kg: 600,000 U intramuscular; ≥ 27 kg: 1,200,000 U intramuscular (1 dose).
- If the patient has a Penicillin Allergy:
- Cephalexin is 20 mg/kg orally twice daily (max 500 mg/dose) for 10 days.
- Cefadroxil is 30 mg/kg/day orally (max 1g) for 10 days.
- Clindamycin is 7 mg/kg orally three times a day (max 300 mg/dose) for 10 days.
- Azithromycin is 12 mg/kg/day orally (max 500 mg) for 5 days.
- Clarithromycin is 7.5 mg/kg orally twice daily (max 250 mg/dose) for 10 days.
- Adjunctive therapy is using Acetaminophen or NSAIDs.
- Avoid aspirin in children and Corticosteroids are not recommended
- Rheumatic fever is a delayed sequela of some GAS infections
- It is an immune response, not an infection
- Rheumatic fever is the leading cause of pediatric acquired heart disease in some countries
- It can occur 1-5 weeks after initial infection
- Symptoms: fever, arthritis, chest pain, shortness of breath, tachycardia, fatigue, chorea, nodules, rash, heart murmur, enlarged heart, fluid around the heart
- Most common ages are 5-15 years old
- Rheumatic fever can be treated with treatment of underlying GAS and symptom management
- Goals of therapy:
- Prevent spread of infection to others
- Infection resolution
- Minimize treatment adverse effects
- Prevent rheumatic fever
- Clinical Practice Guidelines include Infectious Diseases Society of America (IDSA) – 2012 regarding the management of Group A Streptococcal Pharyngitis
Bronchitis
- Acute bronchitis involves inflammation and mucus in the airways in the lungs, and can last up to 3 weeks.
- Bronchitis is characterized by persistent cough, and is also described as a "chest cold".
- 5% of the U.S. population reports acute bronchitis annually.
- Acute bronchitis accounts for > 10 million office visits annually.
- Most cases of bronchitis is commonly caused by a virus.
- A bacterial cause is seen in 1-10% of cases.
- Symptoms include cough (+/- mucus), nasal congestion, chest soreness, fatigue, headache, body aches, sore throat, and fever.
- Symptom duration is typically 2-3 weeks (18 days).
- Laboratory testing is not indicated, and infrequent leukocytosis is seen.
- Specific pathogen testing is only needed if highly suspicious and treatment would be impacted.
- Treatment involves supportive care and symptom management.
- It is recommended against the use of antibiotics, with the exception of pertussis (macrolide).
- Symptomatic management: fluids, rest, humidifier/cool mist vaporizer, nasal saline, breathe in steam, lozenges, honey.
- OTC medications can be used, such as (APAP, ibuprofen, antihistamines, decongestants), but there is minimal benefit.
- Avoid antihistamines and antitussives in young children
- Findings Suggestive of Pneumonia:
- Tachypnea
- Tachycardia
- Dyspnea
- Radiologic findings
- Clinical Practice Resource: American Academy of Family Physician – Acute Bronchitis (2012).
Antibiotic Overprescribing
- Risks of Overprescribing
- Adverse effects
- Antimicrobial resistance
- Unnecessary costs
- Strategies to Reduce Inappropriate Antibiotic Use
- Delayed prescription strategies
- Address patient concerns in a compassionate manner
- Expected course of illness and cough duration
- Explain that antibiotics do not significantly shorten illness duration and are associated with adverse effects and antibiotic resistance
- Discuss the use of nonantibiotic medications to control symptoms
- Describe the infection as a viral illness or chest cold
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