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Understanding Haemolytic Anaemia and Haemolysis

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Understanding Haemolytic Anaemia and Haemolysis

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Questions and Answers

What is the normal lifespan of red blood cells?

120 days (correct)

60 days

90 days

30 days

What is the primary mechanism by which the bone marrow compensates for haemolytic anaemia?

Increasing the proportion of red cells produced

Expanding the volume of active marrow

Releasing reticulocytes prematurely

All of the above (correct)

What is the primary fate of free haemoglobin released during intravascular haemolysis?

It is bound by haptoglobin (correct)

It is toxic to cells

It is excreted by the kidneys

It is broken down by the liver

What is the primary cause of intravascular haemolysis?

All of the above (D) Signup and view all the answers

What is the primary function of haptoglobin during intravascular haemolysis?

To bind and remove free haemoglobin from the plasma (A) Signup and view all the answers

What is the spectrophotometric test used to detect methaemalbumin?

Schumm's test (D) Signup and view all the answers

In what form is free haemoglobin oxidized when haptoglobins are saturated?

Methaemoglobin (A) Signup and view all the answers

What protein binds to methaemoglobin to form methaemalbumin?

Albumin (C) Signup and view all the answers

What gives rise to haemosiderinuria, which indicates intravascular haemolysis?

Sloughed renal tubular cells containing haemosiderin (D) Signup and view all the answers

What happens when free haemoglobin appears in the urine due to saturation of protective mechanisms?

Haemoglobinuria occurs (C) Signup and view all the answers