Hemolytic Anemia and Haemolysis Quiz
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Questions and Answers

What is the definition of hemolysis?

  • A state with a substantially short lifespan of a mature red blood cell. (correct)
  • A process that leads to increased red cell output from the marrow.
  • A process that stimulates the production of erythropoietin.
  • A state with a substantially long lifespan of a mature red blood cell.

How can hemolysis with marked reduction in red cell lifespan be compensated?

  • By increasing erythropoietin production.
  • By increasing red cell lifespan.
  • By reducing red cell output from the marrow.
  • By stimulating erythropoietin production. (correct)

Which type of hemolysis results in increased red cell output from the marrow?

  • Intravascular hemolysis (correct)
  • Extravascular hemolysis
  • Autoimmune hemolysis
  • Non-immune acquired hemolysis

What is a major example of a congenital disorder resulting in hemolysis?

<p>Hereditary spherocytosis (A)</p> Signup and view all the answers

What role do autoantibodies play in the production of hemolytic anemias?

<p>They contribute to the destruction of red blood cells. (C)</p> Signup and view all the answers

What is a cause of non-immune acquired hemolytic anemias?

<p>Malaria infection (C)</p> Signup and view all the answers

Which process involves the macrophages in the spleen, liver, and bone marrow reticuloendothelial system removing red cells from the circulation by phagocytosis?

<p>Extravascular hemolysis (D)</p> Signup and view all the answers

What is the characteristic of red cell destruction in intravascular hemolysis?

<p>Red cell fragmentation (D)</p> Signup and view all the answers

Which laboratory evidence indicates increased red cell breakdown?

<p>Rise in unconjugated bilirubin concentration (C)</p> Signup and view all the answers

What is the indication of increased erythropoietic activity in the blood?

<p>Increased reticulocyte count (A)</p> Signup and view all the answers

Which type of hemolysis is associated with spherocytosis on the peripheral blood film?

<p>Extravascular hemolysis (A)</p> Signup and view all the answers

What happens to the marrow's demand for folic acid as a result of haemolysis?

<p>It increases (B)</p> Signup and view all the answers

What characterizes the bone marrow showing erythroid hyperplasia?

<p>Hypercellular appearance (A)</p> Signup and view all the answers

What does an increase in the absolute reticulocyte count indicate?

<p>Erythropoietic activity (C)</p> Signup and view all the answers

What indicates features of increased red cell production?

<p>Reticulocytosis (B)</p> Signup and view all the answers

What does a rise in the unconjugated bilirubin concentration in the plasma indicate?

<p>Increased red cell breakdown (C)</p> Signup and view all the answers

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