Hemolytic Anemia and Haemolysis Quiz
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Questions and Answers

What is the definition of hemolysis?

  • A state with a substantially short lifespan of a mature red blood cell. (correct)
  • A process that leads to increased red cell output from the marrow.
  • A process that stimulates the production of erythropoietin.
  • A state with a substantially long lifespan of a mature red blood cell.

    • How can hemolysis with marked reduction in red cell lifespan be compensated?

  • By increasing erythropoietin production.
  • By increasing red cell lifespan.
  • By reducing red cell output from the marrow.
  • By stimulating erythropoietin production. (correct)

    • Which type of hemolysis results in increased red cell output from the marrow?

  • Intravascular hemolysis (correct)
  • Extravascular hemolysis
  • Autoimmune hemolysis
  • Non-immune acquired hemolysis

    • What is a major example of a congenital disorder resulting in hemolysis?

    <p>Hereditary spherocytosis</p> Signup and view all the answers

    What role do autoantibodies play in the production of hemolytic anemias?

    <p>They contribute to the destruction of red blood cells.</p> Signup and view all the answers

    What is a cause of non-immune acquired hemolytic anemias?

    <p>Malaria infection</p> Signup and view all the answers

    Which process involves the macrophages in the spleen, liver, and bone marrow reticuloendothelial system removing red cells from the circulation by phagocytosis?

    <p>Extravascular hemolysis</p> Signup and view all the answers

    What is the characteristic of red cell destruction in intravascular hemolysis?

    <p>Red cell fragmentation</p> Signup and view all the answers

    Which laboratory evidence indicates increased red cell breakdown?

    <p>Rise in unconjugated bilirubin concentration</p> Signup and view all the answers

    What is the indication of increased erythropoietic activity in the blood?

    <p>Increased reticulocyte count</p> Signup and view all the answers

    Which type of hemolysis is associated with spherocytosis on the peripheral blood film?

    <p>Extravascular hemolysis</p> Signup and view all the answers

    What happens to the marrow's demand for folic acid as a result of haemolysis?

    <p>It increases</p> Signup and view all the answers

    What characterizes the bone marrow showing erythroid hyperplasia?

    <p>Hypercellular appearance</p> Signup and view all the answers

    What does an increase in the absolute reticulocyte count indicate?

    <p>Erythropoietic activity</p> Signup and view all the answers

    What indicates features of increased red cell production?

    <p>Reticulocytosis</p> Signup and view all the answers

    What does a rise in the unconjugated bilirubin concentration in the plasma indicate?

    <p>Increased red cell breakdown</p> Signup and view all the answers

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