Understanding Diabetes Mellitus

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Questions and Answers

What is the initial entry of glucose into the pancreatic β cell facilitated by?

  • Osmosis
  • Facilitated diffusion (correct)
  • Simple diffusion
  • Active transport

What is the primary regulator of glucose metabolism and storage?

  • Glucagon
  • Insulin (correct)
  • Glycolysis
  • Adenosine triphosphate

Which cells release glucagon-like peptide-1 (GLP-1) following a meal?

  • β cells
  • L cells (correct)
  • Pancreatic β cells
  • K cells

What causes closure of an ATP-sensitive potassium channel (KATP) in the pancreatic β cell?

<p>Increased intracellular adenosine triphosphate (ATP) (D)</p> Signup and view all the answers

What is insulin synthesized as in the pancreatic β cell?

<p>Pro-insulin (C)</p> Signup and view all the answers

How is insulin secreted from pancreatic β cells into the portal circulation?

<p>Facilitated diffusion (C)</p> Signup and view all the answers

What is the primary characteristic of diabetes mellitus?

<p>Chronic hyperglycemia (B)</p> Signup and view all the answers

What triggers insulin secretion in the pancreatic β cell?

<p>Increased intracellular calcium (C)</p> Signup and view all the answers

What is insulin synthesized as in the pancreatic β cell?

<p>Pro-insulin (B)</p> Signup and view all the answers

Which hormones released after a meal activate receptors on the pancreatic β cells to augment insulin secretion?

<p>Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) (D)</p> Signup and view all the answers

What causes closure of an ATP-sensitive potassium channel (KATP) in the pancreatic β cell?

<p>Increased intracellular adenosine triphosphate (ATP) (A)</p> Signup and view all the answers

What is the primary regulator of glucose metabolism and storage?

<p>Insulin (A)</p> Signup and view all the answers

What triggers insulin secretion in the pancreatic β cell?

<p>Calcium release by voltage-sensitive calcium channels (C)</p> Signup and view all the answers

What is insulin synthesized as in the pancreatic β cell?

<p>Pro-insulin (A)</p> Signup and view all the answers

Which hormones released after a meal activate receptors on the pancreatic β cells to augment insulin secretion?

<p>Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) (C)</p> Signup and view all the answers

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