Diabetes Mellitus: Metabolic Disorder and Insulin Regulation
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Questions and Answers

What is the primary regulator of glucose metabolism and storage?

  • Glucagon
  • Insulin (correct)
  • Gastric inhibitory polypeptide (GIP)
  • Glycolysis
  • Which hormones released from gastrointestinal L cells and K cells activate receptors on the pancreatic β cells to augment insulin secretion?

  • Insulin-like growth factor 1 (IGF-1) and insulin-like growth factor 2 (IGF-2)
  • Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) (correct)
  • Insulin and glucagon-like peptide-1 (GLP-1)
  • Glucagon and somatostatin
  • What causes closure of an ATP-sensitive potassium channel (KATP) in the pancreatic β cell?

  • Glycolysis
  • Decreased intracellular ATP
  • Increased intracellular ATP (correct)
  • Voltage-sensitive potassium channels
  • How is glucose transported into the pancreatic β cell?

    <p>Facilitated diffusion</p> Signup and view all the answers

    What is insulin initially synthesized as in the pancreatic β cell?

    <p>Pro-insulin</p> Signup and view all the answers

    Which process results in the closure of an ATP-sensitive potassium channel (KATP) in the pancreatic β cell?

    <p>Glycolysis and oxidative phosphorylation</p> Signup and view all the answers

    What is the primary regulator of glucose metabolism and storage in the body?

    <p>Insulin</p> Signup and view all the answers

    What triggers insulin secretion in the pancreatic β cell?

    <p>Closure of ATP-sensitive potassium channel (KATP)</p> Signup and view all the answers

    Which hormones released from gastrointestinal L cells and K cells activate receptors on the pancreatic β cells to augment insulin secretion?

    <p>Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP)</p> Signup and view all the answers

    What is insulin initially synthesized as in the pancreatic β cell?

    <p>Pro-insulin</p> Signup and view all the answers

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