Diabetes Mellitus: Metabolic Disorder and Insulin Regulation
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Diabetes Mellitus: Metabolic Disorder and Insulin Regulation

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@UnwaveringMachuPicchu

Questions and Answers

What is the primary regulator of glucose metabolism and storage?

Insulin

Which hormones released from gastrointestinal L cells and K cells activate receptors on the pancreatic β cells to augment insulin secretion?

Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP)

What causes closure of an ATP-sensitive potassium channel (KATP) in the pancreatic β cell?

Increased intracellular ATP

How is glucose transported into the pancreatic β cell?

<p>Facilitated diffusion</p> Signup and view all the answers

What is insulin initially synthesized as in the pancreatic β cell?

<p>Pro-insulin</p> Signup and view all the answers

Which process results in the closure of an ATP-sensitive potassium channel (KATP) in the pancreatic β cell?

<p>Glycolysis and oxidative phosphorylation</p> Signup and view all the answers

What is the primary regulator of glucose metabolism and storage in the body?

<p>Insulin</p> Signup and view all the answers

What triggers insulin secretion in the pancreatic β cell?

<p>Closure of ATP-sensitive potassium channel (KATP)</p> Signup and view all the answers

Which hormones released from gastrointestinal L cells and K cells activate receptors on the pancreatic β cells to augment insulin secretion?

<p>Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP)</p> Signup and view all the answers

What is insulin initially synthesized as in the pancreatic β cell?

<p>Pro-insulin</p> Signup and view all the answers

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