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Questions and Answers
What characterizes cancer as a disease?
What is the term used to describe new growth of tissue that serves no physiological function?
Which type of cancer is characterized by cancerous cells in the blood-forming tissues?
What process describes the ability of malignant tumors to spread to other organs?
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Which of the following types of cancer is typically a result of mutated epithelial cells?
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What term is used for the microscopic examination of cell development?
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What type of cancer is characterized by a malignant tumor of connective tissue?
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What stage of cancer is indicated when a tumor is classified as benign?
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Which agent is associated with the highest estimated number of cancer cases worldwide in 2000?
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Which of the following infections is linked to non-Hodgkin lymphoma cases?
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What percentage of worldwide cancer cases in 2000 was attributed to stomach cancer related to H.pylori?
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Which of the following agents is NOT listed as a chemical cause of cancer?
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What lifestyle factor significantly contributes to obesity-related cancers?
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Which type of external cause is directly attributed to skin cancer?
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Which of the following factors can increase the risk of cancer due to occupational exposure?
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What percentage of lung cancers is attributed to smoking?
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What percentage of cancers is believed to be hereditary?
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What is the primary external factor contributing to cancer deaths?
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Which type of cancer is linked to the BRCA 1&2 genes?
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Which virus is associated with cervical cancer?
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Which of these factors has been shown to decrease the risk of breast cancer?
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Which of the following cancers show familial patterns?
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What role does the Helicobacter pylori bacteria play in cancer?
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Which of the following lifestyle factors is NOT considered a risk for cancer?
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What is the lifetime risk concerning cancer?
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What intrinsic factor can influence cancer development in individuals?
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Study Notes
What Is Cancer?
- Cancer is a group of diseases marked by uncontrolled abnormal cell growth and spread
- Neoplasm is a new tissue growth with no physiological function
- Tumor is a clump of neoplasmic cells
- Malignant tumor is cancerous
- Benign tumor is noncancerous
- Biopsy is a microscopic examination of cell development
- Metastasis is the spread of malignant tumors that are not enclosed in a protective capsule to other organs
- Mutant cells are abnormal cells with disrupted RNA and DNA, causing changes in form, quality, and function
Types of Cancer
- Carcinomas are cancers of epithelial tissue
- Sarcomas are cancers of connective tissue
- Lymphomas are cancers of the lymphatic system
- Leukemias are cancers of blood-forming tissues
- Adenomas are tumors of glandular epithelial tissue
- Specific cell names often prefix the cancer type
What Causes Cancer?
- External Factors: Chemicals, radiation, viruses, and lifestyle
- Internal Factors: Hormones, immune conditions, and inherited mutations
- Cellular change/mutation theories propose that cancer arises from genetic changes
- Carcinogens are cancer-causing agents
- Oncogenes and protooncogenes are genes that can regulate cell growth and development, and mutations in these genes can contribute to cancer
Risks For Cancer
- Lifetime risk is the probability of developing or dying from cancer over a lifetime
- Relative risk measures how strongly risk factors are related to a specific cancer
- Smoking is linked to 30% of all cancer deaths and 87% of lung cancer deaths
- Obesity increases the risk of breast and colon cancer
Carcinogenesis
- Heredity plays a role in 5-10% of cancers, and potentially 15% of all cancers
- Genes like RB1, APC, HNPCC, BRCA1 & 2, and p53 have been linked to familial cancer syndromes
Biological Factors
- Breast, stomach, colon, prostate, uterus, ovary, and lung cancers can be familial
- Hodgkin’s disease and certain leukemias also show familial patterns
Immunity
- HIV/AIDS and immunosuppression increase cancer risk
Reproductive And Hormonal Risks
- Pregnancy and oral contraceptives can increase breast cancer risk
- Late menarche, early menopause, early childbirth, and having many children can reduce breast cancer risk
Virus’s
- Hepatitis B, human T-cell leukemia virus (HTLV), Epstein-Barr virus (EBV), and human papillomavirus (HPV) are associated with cancer
Viral Factors
- Herpes-related viruses may be involved in leukemia, Hodgkin’s disease, cervical cancer, and Burkitt’s lymphoma
- EBV, associated with mononucleosis, may contribute to cancer
- HPV, causing genital warts, is linked to cervical cancer
- Helicobacter pylori, causing ulcers, is a major factor in stomach cancer
Bacterial Factors
- H. pylori is linked to stomach cancer
- Parasites like Schistosoma spp. and Clonorchis sinensis can increase cancer risk
Chemical Causes
- Alcohol, asbestos, wood dust, rubber, plastics, dyes, tar, bitumen, aflatoxin, alkylating agents, and tobacco are known carcinogens
External causes of cancer: ultraviolet radiation
- Sunlight and certain industrial sources emit ultraviolet radiation, which can contribute to cancer
Physical Causes
- Ultraviolet radiation from sunlight and industrial sources can cause cancer
- Radiation exposure from radon and cancer treatment can also increase cancer risk
Lifestyle factors: diet
- High caloric diet, rich in fat, refined carbohydrates, and animal protein, combined with low physical activity, can increase cancer risk
Obesity
- Obesity increases the risk of cancer, diabetes, cardiovascular disease, and hypertension
Lifestyle
- Age, occupation, ethnicity, and deprivation can affect cancer risk
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Description
This quiz explores the fundamentals of cancer, including its definitions, types, and causes. Learn about malignant and benign tumors, the different classifications of cancer, and the factors that contribute to its development. Test your knowledge on important terms and concepts related to this complex disease.
