Understanding Animal Research Environment Parameters

What are the parameters to monitor for the animal room environment?

What is the recommended range for humidity in the animal room environment?

How many fresh air changes per hour are recommended for ventilation in the animal room environment?

What is the maximum recommended noise level in decibels for the animal room environment?

At what level should lighting be maintained in lux at 1 meter above the floor in the animal room environment?

What are considered under physical plant life support in the animal room environment?

What is the maximum foot candles level at cage level in the animal room environment?

What is the recommended range for humidity in the animal room environment?

How often should monitoring be done for ventilation in the animal room environment?

What should be done with vibration sources in the animal room environment?

What are the main considerations for the physical factors of housing?

What is the primary purpose of enrichment in animal housing?

What does the term 'Macro Environment' in animal research environment primarily refer to?

Which factor is crucial in determining the cleaning frequency in animal housing?

What is the main purpose of bedding in animal housing?

What are the key aspects of water management in animal housing?

What should be considered while designing the housing for animals?

What is the primary purpose of monitoring & trend tracking in animal research environments?

What is the significance of microenvironment in animal housing?

Why is it important to consider species-specific behavior & special considerations in animal housing?

What are key environmental factors to consider in the animal research environment?

What is the definition of poikilothermic animals as per the text?

What is the purpose of a life support system (LSS) in the animal research environment?

What are zoonoses as mentioned in the text?

How can laboratory animal allergens (LAA) be prevented?

What is sharps waste as discussed in the text?

What is a priority concerning employee safety in animal research?

What are some common lab animal sources of laboratory animal allergens (LAA)?

Temperature, ______, Humidity Air Quality

Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ Vibration:

Building materials: ▵ ▵ ▵ Heating ▵ ▵ Cooling ▵ ▵ Lighting ▵ ▵ Security ▵ ▵ ▵ Efficient and hygienic.

Guide, ______ in response to Air Quality Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ Vibration:

Table 30-70% ▵ Ventilation: 10-15 fresh air changes/hr.

SA2210 Laboratory Animal Technical Skills Part III: Understanding the Animal Research Environment Part III: Understanding the Animal Research Environment MacroEnvironment “ Macroenvironment: The physical environment of the secondary enclosure (e.g., a room, a barn, or an outdoor habitat)

Determining Animal Room Environment Parameters 1. What to Monitor 2. Setpoints 3. Methods 4. How of Monitoring Often to Monitor

Level (lux) Location 325 1 m above floor Up to 400 1 m above floor empty room 130-325 Cage

______ Life Support ▵ Maintenance ▵ Replacement ▵ Backup power ▵

Basics ▵ Temperature, ▵ Ventilation, Humidity Air Quality ▵ Lighting ▵ Noise, Vibration ▵ Additional ▵ Life Considerations Support ▵

Animal research environments require cleaning and enrichment for reproduction and animal needs, while also ensuring safety considerations

The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

Environmental safety involves ______ contamination and pollution of the research environment and the wider community

Sharps waste includes ______ and other sharp objects, and must be handled and disposed of following specific procedures

Zoonoses are diseases that can be ______ from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others

Laboratory animal allergens (LAA) are ______ reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people

NHPs (non-human primates) can be ______ diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals

Animals in research include ______ that intermingle with microorganisms, with varying responses, in a controlled environment

Key environmental ______ include humidity, ventilation, temperature, noise and vibration, and lighting

MicroEnvironment: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders

Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture

Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, Acidified)

Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction

Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, Pans)

Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude Mice

Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, Fire resistant

Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not

Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded

Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, Notification Monitoring of Issues

Temperature, ______, Humidity Air Quality

Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ ______

What is the maximum recommended noise level in decibels for the animal room environment?

What should be done with vibration sources in the animal room environment?

What is sharps waste as discussed in the text?

What is the recommended range for humidity in the animal room environment?

What is the primary purpose of enrichment in animal housing?

What are key environmental factors to consider in the animal research environment?

What does the term 'Macro Environment' in animal research environment primarily refer to?

The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

Animal Research Environment: ______, Macro Environment, Importance of Planning, Assessment of animal needs in primary and secondary enclosures

Housing Design: Sharp Edges, Impair Ability to ______, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture

Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, ______, Extruded

Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, ______ Monitoring of Issues

Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or ______

Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social ______

Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, ______)

Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, ______)

Housing Density: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental ______

Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude ______

Animals in research include macro-organisms that ______ with microorganisms, with varying responses, in a controlled environment

Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature

The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

Zoonoses are diseases that can be ______ from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others

NHPs (non-human primates) can be ______ diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals

Laboratory animal allergens (LAA) are ______ related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people

Common lab animal sources of LAA include ______

Disposal by licensed vendors involves the government-licensed ______ of wastes

Environmental safety involves ______ and pollution of the research environment and the wider community

Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

Common lab animal sources of LAA include ______

Animals in research include macro-organisms that ______ with microorganisms, with varying responses, in a controlled environment

Building materials: ▵ ▵ ▵ Heating ▵ ▵ Cooling ▵ ▵ Lighting ▵ ▵ Security ▵ ▵ ▵ Efficient and hygienic.

Basics ▵ Temperature, ▵ Ventilation, Humidity Air Quality ▵ Lighting ▵ Noise, Vibration ▵ Additional ▵ Life Considerations Support ▵

Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ Vibration:

What is the primary purpose of enrichment in animal housing?

What are the main considerations for the physical factors of housing?

What is the main purpose of bedding in animal housing?

Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, ______

Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature

The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

Employee safety is a priority in animal research, with prevention of ______, sickness, and injury for both humans and animals

Zoonoses are diseases that can be ______ from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others

NHPs (non-human primates) can be ______ diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals

Laboratory animal allergens (LAA) are ______ reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people

Common lab animal sources of LAA include ______

Disposal by licensed vendors involves the government-licensed ______ of wastes

Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

Environmental safety involves preventing ______ and pollution of the research environment and the wider community

SA2210 Laboratory Animal Technical Skills Part III: Understanding the Animal Research Environment Part III: Understanding the Animal Research Environment MacroEnvironment

Determining Animal Room Environment Parameters

Determining What to Monitor

Determining Setpoints versus What is the Minimum

Level (lux) Location 325 1 m above floor Up to 400 1 m above floor empty room 130-325 Cage Level

Physical Plant Life Support