Understanding Animal Research Environment Parameters
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Questions and Answers

What are the parameters to monitor for the animal room environment?

  • Ventilation, air quality, lighting, physical plant life support
  • Temperature, ventilation, humidity, air quality, lighting, noise, vibration (correct)
  • Humidity, air quality, lighting, physical plant life support
  • Temperature, humidity, air quality, noise, vibration, physical plant life support

    • What is the recommended range for humidity in the animal room environment?

  • 10-60%
  • 30-70% (correct)
  • 40-80%
  • 20-50%

    • How many fresh air changes per hour are recommended for ventilation in the animal room environment?

  • 10-15 (correct)
  • 5-10
  • 20-25
  • 15-20

    • What is the maximum recommended noise level in decibels for the animal room environment?

    <p>85 decibels</p> Signup and view all the answers

    At what level should lighting be maintained in lux at 1 meter above the floor in the animal room environment?

    <p>325</p> Signup and view all the answers

    What are considered under physical plant life support in the animal room environment?

    <p>Maintenance, replacement, backup power, building materials, heating, cooling, lighting, security</p> Signup and view all the answers

    What is the maximum foot candles level at cage level in the animal room environment?

    <p>130-325</p> Signup and view all the answers

    What is the recommended range for humidity in the animal room environment?

    <p>30-70%</p> Signup and view all the answers

    How often should monitoring be done for ventilation in the animal room environment?

    <p>Regularly throughout the day</p> Signup and view all the answers

    What should be done with vibration sources in the animal room environment?

    <p>Identify all sources and isolate or dampen them with vibration suppression systems.</p> Signup and view all the answers

    What are the main considerations for the physical factors of housing?

    <p>Toxicity, Security, Corrosion resistance, Ease of cleaning</p> Signup and view all the answers

    What is the primary purpose of enrichment in animal housing?

    <p>Promote psychological well-being and prevent stress</p> Signup and view all the answers

    What does the term 'Macro Environment' in animal research environment primarily refer to?

    <p>Temperature, Humidity, Air Quality, Lighting, Noise, Vibration</p> Signup and view all the answers

    Which factor is crucial in determining the cleaning frequency in animal housing?

    <p>Housing density and husbandry practices</p> Signup and view all the answers

    What is the main purpose of bedding in animal housing?

    <p>Absorb urine &amp; feces and decrease microorganism growth</p> Signup and view all the answers

    What are the key aspects of water management in animal housing?

    <p>Drinking source (Bottle or Automatic), Potable &amp; Uncontaminated water source, Water treatment (Filtered, Autoclaved)</p> Signup and view all the answers

    What should be considered while designing the housing for animals?

    <p>Accessibility to Food &amp; Water, Slip Resistant, Solid, Perforated, Slated, Smooth texture</p> Signup and view all the answers

    What is the primary purpose of monitoring & trend tracking in animal research environments?

    <p>Physical Monitoring, Online/Digital monitoring for notification of issues</p> Signup and view all the answers

    What is the significance of microenvironment in animal housing?

    <p>Prevent abnormal brain development, physiologic dysfunction &amp; behavioral disorders</p> Signup and view all the answers

    Why is it important to consider species-specific behavior & special considerations in animal housing?

    <p>To meet the unique needs of different animals based on their natural behaviors</p> Signup and view all the answers

    What are key environmental factors to consider in the animal research environment?

    <p>Humidity, ventilation, temperature, noise and vibration, and lighting</p> Signup and view all the answers

    What is the definition of poikilothermic animals as per the text?

    <p>Animals that vary their internal body temperature based on external environmental temperature</p> Signup and view all the answers

    What is the purpose of a life support system (LSS) in the animal research environment?

    <p>To provide water as a key factor for the animals, requiring water sources, maintenance, and filtration</p> Signup and view all the answers

    What are zoonoses as mentioned in the text?

    <p>Diseases that can be transmitted from animals to humans</p> Signup and view all the answers

    How can laboratory animal allergens (LAA) be prevented?

    <p>Through work uniforms, PPE (personal protective equipment), ventilated work stations, and hygienic behavior</p> Signup and view all the answers

    What is sharps waste as discussed in the text?

    <p>Needles and other sharp objects used in animal research that must be handled and disposed of following specific procedures</p> Signup and view all the answers

    What is a priority concerning employee safety in animal research?

    <p>Prevention of exposure, sickness, and injury for both humans and animals</p> Signup and view all the answers

    What are some common lab animal sources of laboratory animal allergens (LAA)?

    <p>Mice, rats, rabbits, cats, guinea pigs, and dogs.</p> Signup and view all the answers

    Temperature, ______, Humidity Air Quality

    <p>Ventilation</p> Signup and view all the answers

    Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ Vibration:

    <p>Location</p> Signup and view all the answers

    Building materials: ▵ ▵ ▵ Heating ▵ ▵ Cooling ▵ ▵ Lighting ▵ ▵ Security ▵ ▵ ▵ Efficient and hygienic.

    <p>Maintenance</p> Signup and view all the answers

    Guide, ______ in response to Air Quality Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ Vibration:

    <p>8th Edition</p> Signup and view all the answers

    Table 30-70% ▵ Ventilation: 10-15 fresh air changes/hr.

    <p>Humidity</p> Signup and view all the answers

    SA2210 Laboratory Animal Technical Skills Part III: Understanding the Animal Research Environment Part III: Understanding the Animal Research Environment MacroEnvironment “ Macroenvironment: The physical environment of the secondary enclosure (e.g., a room, a barn, or an outdoor habitat)

    <p>Environment Parameters</p> Signup and view all the answers

    Determining Animal Room Environment Parameters 1. What to Monitor 2. Setpoints 3. Methods 4. How of Monitoring Often to Monitor

    <p>5</p> Signup and view all the answers

    Level (lux) Location 325 1 m above floor Up to 400 1 m above floor empty room 130-325 Cage

    <p>Life Support</p> Signup and view all the answers

    ______ Life Support ▵ Maintenance ▵ Replacement ▵ Backup power ▵

    <p>Physical Plant</p> Signup and view all the answers

    Basics ▵ Temperature, ▵ Ventilation, Humidity Air Quality ▵ Lighting ▵ Noise, Vibration ▵ Additional ▵ Life Considerations Support ▵

    <p>What to Monitor</p> Signup and view all the answers

    Animal research environments require cleaning and enrichment for reproduction and animal needs, while also ensuring safety considerations

    <p>maintenance</p> Signup and view all the answers

    The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

    <p>filtration</p> Signup and view all the answers

    Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

    <p>contaminated</p> Signup and view all the answers

    Environmental safety involves ______ contamination and pollution of the research environment and the wider community

    <p>preventing</p> Signup and view all the answers

    Sharps waste includes ______ and other sharp objects, and must be handled and disposed of following specific procedures

    <p>needles</p> Signup and view all the answers

    Zoonoses are diseases that can be ______ from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others

    <p>transmitted</p> Signup and view all the answers

    Laboratory animal allergens (LAA) are ______ reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people

    <p>allergic</p> Signup and view all the answers

    NHPs (non-human primates) can be ______ diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals

    <p>given</p> Signup and view all the answers

    Animals in research include ______ that intermingle with microorganisms, with varying responses, in a controlled environment

    <p>macro-organisms</p> Signup and view all the answers

    Key environmental ______ include humidity, ventilation, temperature, noise and vibration, and lighting

    <p>factors</p> Signup and view all the answers

    MicroEnvironment: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders

    <p>enrichment</p> Signup and view all the answers

    Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture

    <p>flooring</p> Signup and view all the answers

    Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, Acidified)

    <p>quality</p> Signup and view all the answers

    Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction

    <p>enrichment</p> Signup and view all the answers

    Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, Pans)

    <p>frequency</p> Signup and view all the answers

    Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude Mice

    <p>behavior</p> Signup and view all the answers

    Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, Fire resistant

    <p>materials</p> Signup and view all the answers

    Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not

    <p>bedding</p> Signup and view all the answers

    Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded

    <p>nutrition</p> Signup and view all the answers

    Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, Notification Monitoring of Issues

    <p>monitoring</p> Signup and view all the answers

    Temperature, ______, Humidity Air Quality

    <p>Ventilation</p> Signup and view all the answers

    Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ ______

    <p>Vibration</p> Signup and view all the answers

    What is the maximum recommended noise level in decibels for the animal room environment?

    <p>85</p> Signup and view all the answers

    What should be done with vibration sources in the animal room environment?

    <p>attempts should be made to identify all vibration sources and isolate or dampen them with vibration suppression systems</p> Signup and view all the answers

    What is sharps waste as discussed in the text?

    <p>sharp objects</p> Signup and view all the answers

    What is the recommended range for humidity in the animal room environment?

    <p>30-70%</p> Signup and view all the answers

    What is the primary purpose of enrichment in animal housing?

    <p>Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction</p> Signup and view all the answers

    What are key environmental factors to consider in the animal research environment?

    <p>humidity, ventilation, temperature, noise and vibration, and lighting</p> Signup and view all the answers

    What does the term 'Macro Environment' in animal research environment primarily refer to?

    <p>The physical environment of the secondary enclosure (e.g., a room, a barn, or an outdoor habitat)</p> Signup and view all the answers

    The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

    <p>backup power</p> Signup and view all the answers

    Animal Research Environment: ______, Macro Environment, Importance of Planning, Assessment of animal needs in primary and secondary enclosures

    <p>MicroEnvironment</p> Signup and view all the answers

    Housing Design: Sharp Edges, Impair Ability to ______, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture

    <p>Disinfect/Sanitize</p> Signup and view all the answers

    Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, ______, Extruded

    <p>Fortified</p> Signup and view all the answers

    Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, ______ Monitoring of Issues

    <p>Notification</p> Signup and view all the answers

    Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or ______

    <p>not</p> Signup and view all the answers

    Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social ______

    <p>interaction</p> Signup and view all the answers

    Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, ______)

    <p>Pans</p> Signup and view all the answers

    Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, ______)

    <p>Acidified</p> Signup and view all the answers

    Housing Density: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental ______

    <p>Needs</p> Signup and view all the answers

    Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude ______

    <p>Mice</p> Signup and view all the answers

    Animals in research include macro-organisms that ______ with microorganisms, with varying responses, in a controlled environment

    <p>intermingle</p> Signup and view all the answers

    Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature

    <p>poikilothermic</p> Signup and view all the answers

    The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

    <p>filtration</p> Signup and view all the answers

    Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

    <p>contaminated</p> Signup and view all the answers

    Zoonoses are diseases that can be ______ from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others

    <p>transmitted</p> Signup and view all the answers

    NHPs (non-human primates) can be ______ diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals

    <p>given</p> Signup and view all the answers

    Laboratory animal allergens (LAA) are ______ related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people

    <p>allergic reactions</p> Signup and view all the answers

    Common lab animal sources of LAA include ______

    <p>mice, rats, rabbits, cats, guinea pigs, and dogs</p> Signup and view all the answers

    Disposal by licensed vendors involves the government-licensed ______ of wastes

    <p>incineration</p> Signup and view all the answers

    Environmental safety involves ______ and pollution of the research environment and the wider community

    <p>preventing contamination</p> Signup and view all the answers

    Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

    <p>contaminated</p> Signup and view all the answers

    Common lab animal sources of LAA include ______

    <p>mice, rats, guinea pigs, rabbits, hamsters, gerbils</p> Signup and view all the answers

    Animals in research include macro-organisms that ______ with microorganisms, with varying responses, in a controlled environment

    <p>interact</p> Signup and view all the answers

    Building materials: ▵ ▵ ▵ Heating ▵ ▵ Cooling ▵ ▵ Lighting ▵ ▵ Security ▵ ▵ ▵ Efficient and hygienic.

    <p>ventilation</p> Signup and view all the answers

    Basics ▵ Temperature, ▵ Ventilation, Humidity Air Quality ▵ Lighting ▵ Noise, Vibration ▵ Additional ▵ Life Considerations Support ▵

    <p>humidity</p> Signup and view all the answers

    Determining Setpoints versus What is the Minimum ▵ Lighting: ▵ Noise: lux, foot candles maximum 85 decibel ▵ Vibration:

    <p>temperature</p> Signup and view all the answers

    What is the primary purpose of enrichment in animal housing?

    <p>to provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction</p> Signup and view all the answers

    What are the main considerations for the physical factors of housing?

    <p>NON-Toxicity, Security, Prevent Escape, Prevent Entrapment, Durability, Lack Of Corrosion/Rusting, Stand Up to Regular Cleaning &amp; Handling</p> Signup and view all the answers

    What is the main purpose of bedding in animal housing?

    <p>to allow species-specific behavior, absorb urine &amp; feces, decrease microorganism growth, and decrease gas buildup (ammonia, CO2)</p> Signup and view all the answers

    Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, ______

    <p>Fire resistant</p> Signup and view all the answers

    Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature

    <p>poikilothermic</p> Signup and view all the answers

    The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______

    <p>filtration</p> Signup and view all the answers

    Employee safety is a priority in animal research, with prevention of ______, sickness, and injury for both humans and animals

    <p>exposure</p> Signup and view all the answers

    Zoonoses are diseases that can be ______ from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others

    <p>transmitted</p> Signup and view all the answers

    NHPs (non-human primates) can be ______ diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals

    <p>given</p> Signup and view all the answers

    Laboratory animal allergens (LAA) are ______ reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people

    <p>allergic</p> Signup and view all the answers

    Common lab animal sources of LAA include ______

    <p>mice, rats, rabbits, cats, guinea pigs, and dogs</p> Signup and view all the answers

    Disposal by licensed vendors involves the government-licensed ______ of wastes

    <p>incineration</p> Signup and view all the answers

    Water LSS can be ______ by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine

    <p>contaminated</p> Signup and view all the answers

    Environmental safety involves preventing ______ and pollution of the research environment and the wider community

    <p>contamination</p> Signup and view all the answers

    SA2210 Laboratory Animal Technical Skills Part III: Understanding the Animal Research Environment Part III: Understanding the Animal Research Environment MacroEnvironment

    <p>Macroenvironment: The physical environment of the secondary enclosure (e.g., a room, a barn, or an outdoor habitat)</p> Signup and view all the answers

    Determining Animal Room Environment Parameters

    <ol> <li>What to Monitor 2. Setpoints 3. Methods 4. How of Monitoring Often to Monitor</li> </ol> Signup and view all the answers

    Determining What to Monitor

    <p>Basics Temperature Ventilation Humidity Air Quality Lighting Noise Vibration Additional Life Considerations Support Physical Plant</p> Signup and view all the answers

    Determining Setpoints versus What is the Minimum

    <p>Temperature: Humidity: Table 30-70% Ventilation: 10-15 fresh air changes/hr.</p> Signup and view all the answers

    Level (lux) Location 325 1 m above floor Up to 400 1 m above floor empty room 130-325 Cage Level

    <p>8</p> Signup and view all the answers

    Physical Plant Life Support

    <p>Maintenance Replacement Backup power Building materials Heating Cooling Lighting Security Efficient and hygienic</p> Signup and view all the answers

    Study Notes

    • Part III of the text discusses understanding the animal research environment, focusing on the aquatic, semi-aquatic macro- and micro-environment, safety and oversight, and zoonoses.

    • Animals in research include macro-organisms that intermingle with microorganisms, with varying responses, in a controlled environment.

    • Key environmental factors include humidity, ventilation, temperature, noise and vibration, and lighting.

    • Most animals used in research are poikilothermic, meaning they vary their internal body temperature based on external environmental temperature.

    • Animal research environments require cleaning and enrichment for reproduction and animal needs, while also ensuring safety considerations.

    • Latex gloves and chemical/cleaning agents are used in animal research, with specific procedures for handling and disposal.

    • The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and filtration.

    • Water LSS can be contaminated by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine.

    • Employee safety is a priority in animal research, with prevention of exposure, sickness, and injury for both humans and animals.

    • Environmental safety involves preventing contamination and pollution of the research environment and the wider community.

    • Animal safety includes proper handling, transport, and disposal of animal wastes, biohazardous agents, chemical waste, animal carcasses, and sharps waste.

    • Sharps waste includes needles and other sharp objects, and must be handled and disposed of following specific procedures.

    • Disposal by licensed vendors involves the government-licensed incineration of wastes.

    • Zoonoses are diseases that can be transmitted from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others.

    • NHPs (non-human primates) can be given diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals.

    • Laboratory animal allergens (LAA) are allergic reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people.

    • LAA can be prevented through work uniforms, PPE, ventilated work stations, and hygienic behavior.

    • Common lab animal sources of LAA include mice, rats, rabbits, cats, guinea pigs, and dogs.

    • Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, Fire resistant

    • Related to General Population: Basement vs Upper Floor

    • Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, Notification Monitoring of Issues

    • Animal Research Environment: MicroEnvironment, Macro Environment, Importance of Planning, Assessment of animal needs in primary and secondary enclosures

    • MicroEnvironment: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders

    • Macro Environment: Temperature, Humidity, Ventilation, Air Quality, Lighting, Noise, Vibration

    • Physical Factors of Housing: NON-Toxicity, Security, Prevent Escape, Prevent Entrapment, Durability, Lack Of Corrosion/Rusting, Stand Up to Regular Cleaning & Handling

    • Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture

    • Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded

    • Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not

    • Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, Acidified)

    • Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction

    • Housing Density: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental Needs

    • Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, Pans)

    • Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude Mice.

    Note: These bullet points are designed for a quick reference to the key facts and context presented in the text. They are not an exhaustive list and are not meant to replace reading and understanding the full text.

    • Part III of the text discusses understanding the animal research environment, focusing on the aquatic, semi-aquatic macro- and micro-environment, safety and oversight, and zoonoses.

    • Animals in research include macro-organisms that intermingle with microorganisms, with varying responses, in a controlled environment.

    • Key environmental factors include humidity, ventilation, temperature, noise and vibration, and lighting.

    • Most animals used in research are poikilothermic, meaning they vary their internal body temperature based on external environmental temperature.

    • Animal research environments require cleaning and enrichment for reproduction and animal needs, while also ensuring safety considerations.

    • Latex gloves and chemical/cleaning agents are used in animal research, with specific procedures for handling and disposal.

    • The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and filtration.

    • Water LSS can be contaminated by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine.

    • Employee safety is a priority in animal research, with prevention of exposure, sickness, and injury for both humans and animals.

    • Environmental safety involves preventing contamination and pollution of the research environment and the wider community.

    • Animal safety includes proper handling, transport, and disposal of animal wastes, biohazardous agents, chemical waste, animal carcasses, and sharps waste.

    • Sharps waste includes needles and other sharp objects, and must be handled and disposed of following specific procedures.

    • Disposal by licensed vendors involves the government-licensed incineration of wastes.

    • Zoonoses are diseases that can be transmitted from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others.

    • NHPs (non-human primates) can be given diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals.

    • Laboratory animal allergens (LAA) are allergic reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people.

    • LAA can be prevented through work uniforms, PPE, ventilated work stations, and hygienic behavior.

    • Common lab animal sources of LAA include mice, rats, rabbits, cats, guinea pigs, and dogs.

    • Part III of the text discusses understanding the animal research environment, focusing on the aquatic, semi-aquatic macro- and micro-environment, safety and oversight, and zoonoses.

    • Animals in research include macro-organisms that intermingle with microorganisms, with varying responses, in a controlled environment.

    • Key environmental factors include humidity, ventilation, temperature, noise and vibration, and lighting.

    • Most animals used in research are poikilothermic, meaning they vary their internal body temperature based on external environmental temperature.

    • Animal research environments require cleaning and enrichment for reproduction and animal needs, while also ensuring safety considerations.

    • Latex gloves and chemical/cleaning agents are used in animal research, with specific procedures for handling and disposal.

    • The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and filtration.

    • Water LSS can be contaminated by various factors, such as conductivity, salinity, pH, nitrogenous waste buildup, dissolved oxygen, total gas pressure, and chlorine.

    • Employee safety is a priority in animal research, with prevention of exposure, sickness, and injury for both humans and animals.

    • Environmental safety involves preventing contamination and pollution of the research environment and the wider community.

    • Animal safety includes proper handling, transport, and disposal of animal wastes, biohazardous agents, chemical waste, animal carcasses, and sharps waste.

    • Sharps waste includes needles and other sharp objects, and must be handled and disposed of following specific procedures.

    • Disposal by licensed vendors involves the government-licensed incineration of wastes.

    • Zoonoses are diseases that can be transmitted from animals to humans and include common diseases such as tetanus, rabies, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others.

    • NHPs (non-human primates) can be given diseases, such as measles and TB, and preventing transmission involves a health surveillance program for all people with access to animals.

    • Laboratory animal allergens (LAA) are allergic reactions related to animal proteins in skin, saliva, urine, and feces, and can affect up to 44% of people.

    • LAA can be prevented through work uniforms, PPE, ventilated work stations, and hygienic behavior.

    • Common lab animal sources of LAA include mice, rats, rabbits, cats, guinea pigs, and dogs.

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