Animal Research Environment Monitoring Quiz

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Questions and Answers

Determining Animal Room Environment Parameters 1. What to Monitor

Basics

Setpoints

Temperature, Humidity, Ventilation

Methods

Air Quality

How of Monitoring Often to Monitor

<p>Life Considerations</p> Signup and view all the answers

Determining Setpoints versus What is the Minimum

<p>Noise</p> Signup and view all the answers

Temperature

<p>Table 30-70%</p> Signup and view all the answers

Humidity

<p>10-15 fresh air changes/hr</p> Signup and view all the answers

Lighting

<p>lux, foot candles maximum 85 decibel</p> Signup and view all the answers

Vibration

<p>attempts should be made to identify all vibration sources and isolate or dampen them with vibration suppression systems</p> Signup and view all the answers

Physical Plant Life Support

<p>Maintenance, Replacement, Backup power, Building materials, Heating, Cooling, Lighting, Security</p> Signup and view all the answers

Part III of the text discusses understanding the animal research environment, focusing on the , semi- macro- and micro-environment, safety and oversight, and zoonoses.

<p>aquatic</p> Signup and view all the answers

Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature.

<p>poikilothermic</p> Signup and view all the answers

Latex gloves and ______/cleaning agents are used in animal research, with specific procedures for handling and disposal.

<p>chemical</p> Signup and view all the answers

The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______.

<p>filtration</p> Signup and view all the answers

Employee safety is a priority in animal research, with prevention of ______, sickness, and injury for both humans and animals.

<p>exposure</p> Signup and view all the answers

Animal safety includes proper handling, transport, and disposal of animal wastes, biohazardous agents, chemical waste, animal carcasses, and ______ waste.

<p>sharps</p> Signup and view all the answers

Disposal by licensed vendors involves the ______ incineration of wastes.

<p>government-licensed</p> Signup and view all the answers

Zoonoses are diseases that can be transmitted from animals to humans and include common diseases such as tetanus, ______, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others.

<p>rabies</p> Signup and view all the answers

Laboratory animal allergens (LAA) are allergic reactions related to animal proteins in skin, ______, urine, and feces, and can affect up to 44% of people.

<p>saliva</p> Signup and view all the answers

Common lab animal sources of LAA include ______, rats, rabbits, cats, guinea pigs, and dogs.

<p>mice</p> Signup and view all the answers

Animal Research Environment: MicroEnvironment, Macro Environment, Importance of ______, Assessment of animal needs in primary and secondary enclosures

<p>Planning</p> Signup and view all the answers

Micro______: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders

<p>Environment</p> Signup and view all the answers

Macro ______: Temperature, Humidity, Ventilation, Air Quality, Lighting, Noise, Vibration

<p>Environment</p> Signup and view all the answers

Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture

<p>Surfaces</p> Signup and view all the answers

Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded

<p>Diet</p> Signup and view all the answers

______: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not

<p>Bedding</p> Signup and view all the answers

______: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, ______ Source (Well, Municipal, etc.), ______ Treatment (Filtered, Autoclaved, Acidified)

<p>Water</p> Signup and view all the answers

______: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction

<p>Enrichment</p> Signup and view all the answers

Housing ______: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental Needs

<p>Density</p> Signup and view all the answers

Species Specific ______ & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging ______, Nesting ______, Remote Monitoring, Nude Mice

<p>Behavior</p> Signup and view all the answers

Flashcards

Bedding

The material used to line the bottom of an animal's cage, providing a surface for them to rest, play, and eliminate waste.

Microenvironment

The specific environment within a cage or enclosure where an animal directly interacts, including its size, structures, and resources.

Macro Environment

The overall environmental conditions surrounding the cage, such as temperature, humidity, and lighting.

Non-Toxic Material

A material used for building cages, floors, and other structures, that is not toxic to the animals being housed.

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Prevent Escape

Designing housing to prevent animals from escaping, like using solid walls or secure lids.

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Cleaning

The process of keeping animals in a clean and hygienic state by removing waste and contaminants.

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Cleaning Frequency

The frequency at which cleaning and maintaining a housing enclosure is performed.

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Housing Density

The density at which animals are housed in a given space, considering factors like social interactions and species needs.

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Monitoring & Trend Tracking

The process of monitoring and recording data about the health and well-being of animals housed in research facilities.

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Species-Specific Behaviors

Animals' natural behaviors that are crucial for their welfare, such as foraging, nesting, and social interactions.

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Physical/Digital Monitoring

The use of physical observation, digital tools, or online platforms to track the health and well-being of animals.

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Notification Monitoring

The ability to detect early warning signs of disease or distress in animal subjects.

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Durability

The ability to withstand wear, tear, and damage, like scratches, bites, or cleaning agents.

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Moisture Proof

The ability to resist moisture and prevent water damage, like from spills or cleaning.

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Vermin Proof

The ability to resist penetration by pests, like rodents or insects.

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Fire Resistant

The ability to resist fire and minimize damage in case of a fire.

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Sanitization

The use of methods and materials to prevent the spread of germs and infection, like disinfecting surfaces.

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Accessibility to Food & Water

The ability of the animal to access food and water easily within its enclosure.

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Slip Resistant

A surface that is designed to prevent slipping, like a textured floor or non-slip mats.

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Solid

A solid object, without any openings or gaps.

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Perforated

A material with numerous small openings, like a mesh cage.

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Slated

A surface made of long, narrow strips laid parallel to each other.

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Smooth

A surface that is smooth and free of bumps or ridges.

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Texture

The texture or feel of a surface, such as smooth, rough, or soft.

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Palatable Food

Food that is palatable, meaning that animals will enjoy eating it. It should also be uncontaminated and meet their nutritional needs.

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Uncontaminated Food

Food that is safe from contaminants that could cause illness, such as bacteria or toxins.

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Nutritionally Adequate Food

Food that is specifically designed to meet the specific nutritional requirements of an animal species.

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Behaviorally Appropriate Food

The ability of food to meet the natural and instinctive eating behaviors of animals, like gnawing or foraging.

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Enrichment

Supplying animals with environmental enrichment, such as toys, structures, or activities, to promote well-being, physical activity, and mental stimulation.

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Water Treatment

The process used to purify or treat water to ensure it is safe and clean for animal consumption.

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Static IVC

A type of housing that utilizes a static, enclosed system that is completely sealed and provides a sterile environment for work with animals.

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Study Notes

  • Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, Fire resistant
  • Related to General Population: Basement vs Upper Floor
  • Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, Notification Monitoring of Issues
  • Animal Research Environment: MicroEnvironment, Macro Environment, Importance of Planning, Assessment of animal needs in primary and secondary enclosures
  • MicroEnvironment: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders
  • Macro Environment: Temperature, Humidity, Ventilation, Air Quality, Lighting, Noise, Vibration
  • Physical Factors of Housing: NON-Toxicity, Security, Prevent Escape, Prevent Entrapment, Durability, Lack Of Corrosion/Rusting, Stand Up to Regular Cleaning & Handling
  • Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture
  • Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded
  • Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not
  • Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, Acidified)
  • Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction
  • Housing Density: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental Needs
  • Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, Pans)
  • Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude Mice.

Note: These bullet points are designed for a quick reference to the key facts and context presented in the text. They are not an exhaustive list and are not meant to replace reading and understanding the full text.

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03 Part III Animal Research Environment.pptx

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