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Determining Animal Room Environment Parameters 1. What to Monitor
Determining Animal Room Environment Parameters 1. What to Monitor
Basics
Setpoints
Setpoints
Temperature, Humidity, Ventilation
Methods
Methods
Air Quality
How of Monitoring Often to Monitor
How of Monitoring Often to Monitor
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Determining Setpoints versus What is the Minimum
Determining Setpoints versus What is the Minimum
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Temperature
Temperature
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Humidity
Humidity
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Lighting
Lighting
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Vibration
Vibration
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Physical Plant Life Support
Physical Plant Life Support
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Part III of the text discusses understanding the animal research environment, focusing on the , semi- macro- and micro-environment, safety and oversight, and zoonoses.
Part III of the text discusses understanding the animal research environment, focusing on the , semi- macro- and micro-environment, safety and oversight, and zoonoses.
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Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature.
Most animals used in research are ______, meaning they vary their internal body temperature based on external environmental temperature.
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Latex gloves and ______/cleaning agents are used in animal research, with specific procedures for handling and disposal.
Latex gloves and ______/cleaning agents are used in animal research, with specific procedures for handling and disposal.
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The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______.
The animal research environment includes a life support system (LSS) with water as a key factor, requiring water sources, maintenance, and ______.
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Employee safety is a priority in animal research, with prevention of ______, sickness, and injury for both humans and animals.
Employee safety is a priority in animal research, with prevention of ______, sickness, and injury for both humans and animals.
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Animal safety includes proper handling, transport, and disposal of animal wastes, biohazardous agents, chemical waste, animal carcasses, and ______ waste.
Animal safety includes proper handling, transport, and disposal of animal wastes, biohazardous agents, chemical waste, animal carcasses, and ______ waste.
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Disposal by licensed vendors involves the ______ incineration of wastes.
Disposal by licensed vendors involves the ______ incineration of wastes.
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Zoonoses are diseases that can be transmitted from animals to humans and include common diseases such as tetanus, ______, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others.
Zoonoses are diseases that can be transmitted from animals to humans and include common diseases such as tetanus, ______, cryptosporidiosis, herpes B, tularemia/rabbit fever, coronaviruses/SARS, hoof stock diseases, and others.
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Laboratory animal allergens (LAA) are allergic reactions related to animal proteins in skin, ______, urine, and feces, and can affect up to 44% of people.
Laboratory animal allergens (LAA) are allergic reactions related to animal proteins in skin, ______, urine, and feces, and can affect up to 44% of people.
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Common lab animal sources of LAA include ______, rats, rabbits, cats, guinea pigs, and dogs.
Common lab animal sources of LAA include ______, rats, rabbits, cats, guinea pigs, and dogs.
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Animal Research Environment: MicroEnvironment, Macro Environment, Importance of ______, Assessment of animal needs in primary and secondary enclosures
Animal Research Environment: MicroEnvironment, Macro Environment, Importance of ______, Assessment of animal needs in primary and secondary enclosures
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Micro______: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders
Micro______: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders
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Macro ______: Temperature, Humidity, Ventilation, Air Quality, Lighting, Noise, Vibration
Macro ______: Temperature, Humidity, Ventilation, Air Quality, Lighting, Noise, Vibration
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Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture
Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture
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Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded
Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded
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______: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not
______: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not
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______: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, ______ Source (Well, Municipal, etc.), ______ Treatment (Filtered, Autoclaved, Acidified)
______: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, ______ Source (Well, Municipal, etc.), ______ Treatment (Filtered, Autoclaved, Acidified)
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______: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction
______: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction
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Housing ______: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental Needs
Housing ______: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental Needs
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Species Specific ______ & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging ______, Nesting ______, Remote Monitoring, Nude Mice
Species Specific ______ & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging ______, Nesting ______, Remote Monitoring, Nude Mice
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Study Notes
- Doors, Windows, Corridors, Floors: Durability, Moisture proof, Vermin proof, Fire resistant
- Related to General Population: Basement vs Upper Floor
- Monitoring & Trend Tracking: Physical Monitoring, Online/Digital, Benefits, Negatives, Notification of Issues, Notification Monitoring of Issues
- Animal Research Environment: MicroEnvironment, Macro Environment, Importance of Planning, Assessment of animal needs in primary and secondary enclosures
- MicroEnvironment: Provide sufficient space, supplementary structures, resources, prevent abnormal brain development, physiologic dysfunction, behavioral disorders
- Macro Environment: Temperature, Humidity, Ventilation, Air Quality, Lighting, Noise, Vibration
- Physical Factors of Housing: NON-Toxicity, Security, Prevent Escape, Prevent Entrapment, Durability, Lack Of Corrosion/Rusting, Stand Up to Regular Cleaning & Handling
- Housing Design: Sharp Edges, Impair Ability to Disinfect/Sanitize, Accessibility to Food & Water, Slip Resistant, Solid, Perforated, Slated, Smooth, Texture
- Food: Palatable, Uncontaminated, Meet Nutritional & Behavioral Needs, Natural Ingredient, Certified, Purified, Chemically Defined, Irradiated, Fortified, Extruded
- Bedding: Allow Species Specific Behavior, Absorb Urine & Feces, Decrease Microorganism Growth, Gas Buildup (ammonia, CO2), Paper (white, newspaper), Wood (aspen, pine, beech/birch/maple blend), Bed-o’Cob, Enrichment mixed in or not
- Water: Drinking Source (Bottle or Automatic), Potable & Uncontaminated, Water Source (Well, Municipal, etc.), Water Treatment (Filtered, Autoclaved, Acidified)
- Enrichment: Provide sensory and motor stimulation, promote psychological well-being, species-specific behaviors, minimize stress, impact overall health, prevent aggression, excessive calories, physical damage to body, social interaction
- Housing Density: Social Needs, Naturally Social or Territorial, Age, Weight, Sex, Experimental Needs
- Cleaning Frequency: Housing Density, Husbandry Practices, Caging Type, Static IVC, Large Animal System, Cage Parts (Bottom Wire Bar, Lid/Filter Top, Water Bottle, Kennels, Pans)
- Species Specific Behavior & Special Considerations: Predator or Prey, Innate Fear Response, Mice & Marbles, Monkey & Snakes, Social Needs, Foraging Behavior, Nesting Behavior, Remote Monitoring, Nude Mice.
Note: These bullet points are designed for a quick reference to the key facts and context presented in the text. They are not an exhaustive list and are not meant to replace reading and understanding the full text.
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Description
Test your understanding of monitoring the physical environment in an animal research facility, including determining what to monitor, setpoints, methods, and frequency of monitoring.
